{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T11:04:10Z","timestamp":1648551850492},"reference-count":32,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncol Lett"],"DOI":"10.3892\/ol.2018.8828","type":"journal-article","created":{"date-parts":[[2018,5,30]],"date-time":"2018-05-30T06:52:50Z","timestamp":1527663170000},"source":"Crossref","is-referenced-by-count":0,"title":["Loss of Raf kinase inhibitor protein expression is associated with human papillomavirus 16 infection in anal tumors"],"prefix":"10.3892","author":[{"given":"Lucas","family":"Bidinotto","sequence":"first","affiliation":[{"name":"Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, SP 14784 400, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"V\ufffdo","sequence":"additional","affiliation":[{"name":"Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, SP 14784 400, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edgar","family":"Loaiza","sequence":"additional","affiliation":[{"name":"Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, SP 14784 400, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guilherme","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, SP 14784 400, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriana","family":"Lorenzi","sequence":"additional","affiliation":[{"name":"Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, SP 14784 400, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciana","family":"Reis Rosa","sequence":"additional","affiliation":[{"name":"Laboratory of Virology, Institute of Tropical Medicine, University of S\ufffdo Paulo, S\ufffdo Paulo, SP 05403 000, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Laboratory of Virology, Institute of Tropical Medicine, University of S\ufffdo Paulo, S\ufffdo Paulo, SP 05403 000, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\ufffd","family":"Levi","sequence":"additional","affiliation":[{"name":"Laboratory of Virology, Institute of Tropical Medicine, University of S\ufffdo Paulo, S\ufffdo Paulo, SP 05403 000, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristovam","family":"Scapulatempo\u2011Neto","sequence":"additional","affiliation":[{"name":"Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, SP 14784 400, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adhemar","family":"Longatto\u2011Filho","sequence":"additional","affiliation":[{"name":"Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, SP 14784 400, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Reis","sequence":"additional","affiliation":[{"name":"Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, SP 14784 400, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2018,5,30]]},"reference":[{"key":"key20200714083042_b1-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"1569","DOI":"10.1200\/JCO.2012.45.2524","article-title":"Changing patterns of anal canal carcinoma in the United States","volume":"31","author":"Nelson","year":"2013","journal-title":"J Clin Oncol"},{"key":"key20200714083042_b2-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3322\/caac.21332","article-title":"Cancer statistics, 2016","volume":"66","author":"Siegel","year":"2016","journal-title":"CA Cancer J Clin"},{"key":"key20200714083042_b3-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1002\/bjs.1800810405","article-title":"Malignant anal tumours","volume":"81","author":"Deans","year":"1994","journal-title":"Br J Surg"},{"key":"key20200714083042_b4-ol-0-0-8828","volume-title":"World Health Organization and International Agency for Research on Cancer: WHO classification of tumours of the digestive system","author":"Bosman","year":"2010"},{"key":"key20200714083042_b5-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1055\/s-0031-1272824","article-title":"Neoplasms of anal canal and perianal skin","volume":"24","author":"Leonard","year":"2011","journal-title":"Clin Colon Rectal Surg"},{"key":"key20200714083042_b6-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"1812","DOI":"10.1200\/JCO.2013.52.3464","article-title":"Human papillomavirus genotyping and p16 expression as prognostic factors for patients with American joint committee on cancer stages I to III carcinoma of the anal canal","volume":"32","author":"Serup-Hansen","year":"2014","journal-title":"J Clin Oncol"},{"key":"key20200714083042_b7-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1097\/QAD.0000000000000603","article-title":"Risk of progression to high-grade anal intraepithelial neoplasia in HIV-infected MSM","volume":"29","author":"Burgos","year":"2015","journal-title":"AIDS"},{"key":"key20200714083042_b8-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1016\/j.ajog.2015.03.034","article-title":"Prevalence of anal human papillomavirus infection and anal HPV-related disorders in women: A systematic review","volume":"213","author":"Stier","year":"2015","journal-title":"Am J Obstet Gynecol"},{"key":"key20200714083042_b9-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1042\/CS20050369","article-title":"Molecular biology of human papillomavirus infection and cervical cancer","volume":"110","author":"Doorbar","year":"2006","journal-title":"Clin Sci (Lond)"},{"key":"key20200714083042_b10-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1002\/path.4656","article-title":"Model systems of human papillomavirus-associated disease","volume":"238","author":"Doorbar","year":"2016","journal-title":"J Pathol"},{"key":"key20200714083042_b11-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"e63","DOI":"10.1038\/emi.2014.62","article-title":"Oncogenes and RNA splicing of human tumor viruses","volume":"3","author":"Ajiro","year":"2014","journal-title":"Emerg Microbes Infect"},{"key":"key20200714083042_b12-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"1098","DOI":"10.1007\/s10620-009-0812-6","article-title":"Molecular biomarkers correlate with disease-free survival in patients with anal canal carcinoma treated with chemoradiation","volume":"55","author":"Ajani","year":"2010","journal-title":"Dig Dis Sci"},{"key":"key20200714083042_b13-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"7207","DOI":"10.1128\/MCB.21.21.7207-7217.2001","article-title":"Raf kinase inhibitor protein interacts with NF-kappaB-inducing kinase and TAK1 and inhibits NF-kappaB activation","volume":"21","author":"Yeung","year":"2001","journal-title":"Mol Cell Biol"},{"key":"key20200714083042_b14-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1038\/43686","article-title":"Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP","volume":"401","author":"Yeung","year":"1999","journal-title":"Nature"},{"key":"key20200714083042_b15-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1038\/nature02158","article-title":"Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2","volume":"426","author":"Lorenz","year":"2003","journal-title":"Nature"},{"key":"key20200714083042_b16-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/S0065-230X(04)91005-6","article-title":"Raf-1 kinase inhibitor protein: Structure, function, regulation of cell signaling, and pivotal role in apoptosis","volume":"91","author":"Odabaei","year":"2004","journal-title":"Adv Cancer Res"},{"key":"key20200714083042_b17-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"2106","DOI":"10.3892\/or.2015.4157","article-title":"Effect of Raf kinase inhibitor protein expression on malignant biological behavior and progression of colorectal cancer","volume":"34","author":"Wang","year":"2015","journal-title":"Oncol Rep"},{"key":"key20200714083042_b18-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1007\/s00428-009-0821-z","article-title":"Loss of RKIP expression is associated with poor survival in GISTs","volume":"455","author":"Martinho","year":"2009","journal-title":"Virchows Arch"},{"key":"key20200714083042_b19-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"690","DOI":"10.3892\/or.2012.2179","article-title":"Absence of RKIP expression is an independent prognostic biomarker for gastric cancer patients","volume":"29","author":"Martinho","year":"2013","journal-title":"Oncol Rep"},{"key":"key20200714083042_b20-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1016\/j.ijrobp.2015.08.004","article-title":"Prognostic relevance of HPV infection and p16 overexpression in squamous cell anal cancer","volume":"93","author":"Mai","year":"2015","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"key20200714083042_b21-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"1358","DOI":"10.1038\/bjc.2015.20","article-title":"HPV-negative squamous cell carcinoma of the anal canal is unresponsive to standard treatment and frequently carries disruptive mutations in TP53","volume":"112","author":"Meulendijks","year":"2015","journal-title":"Br J Cancer"},{"key":"key20200714083042_b22-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"43594","DOI":"10.18632\/oncotarget.6202","article-title":"Comprehensive multiplatform biomarker analysis of 199 anal squamous cell carcinomas","volume":"6","author":"Smaglo","year":"2015","journal-title":"Oncotarget"},{"key":"key20200714083042_b23-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1016\/S1470-2045(10)70130-3","article-title":"Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: A retrospective consortium analysis","volume":"11","author":"de Roock","year":"2010","journal-title":"Lancet Oncol"},{"key":"key20200714083042_b24-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"3791","DOI":"10.3892\/mmr.2016.5684","article-title":"Low mutation percentage of KRAS and BRAF genes in Brazilian anal tumors","volume":"14","author":"Bidinotto","year":"2016","journal-title":"Mol Med Rep"},{"key":"key20200714083042_b25-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"1891","DOI":"10.3892\/ol.2017.5650","article-title":"Characterization of topoisomerase II \u03b1 and minichromosome maintenance protein 2 expression in anal carcinoma","volume":"13","author":"Scapulatempo-Neto","year":"2017","journal-title":"Oncol Lett"},{"key":"key20200714083042_b26-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1159\/000441227","article-title":"Raf kinase inhibitor protein expression and prognostic value in soft tissue sarcomas","volume":"83","author":"Martinho","year":"2016","journal-title":"Pathobiology"},{"key":"key20200714083042_b27-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"2090","DOI":"10.1148\/rg.2015150037","article-title":"Anorectal cancer: Critical anatomic and staging distinctions that affect use of radiation therapy","volume":"35","author":"Matalon","year":"2015","journal-title":"Radiographics"},{"key":"key20200714083042_b28-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.clcc.2015.07.007","article-title":"Comparative survival of patients with anal adenocarcinoma, squamous cell carcinoma of the anus, and rectal adenocarcinoma","volume":"15","author":"Franklin","year":"2016","journal-title":"Clin Colorectal Cancer"},{"key":"key20200714083042_b29-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1007\/DCR.0b013e31819eb7f0","article-title":"Outcomes and prognostic factors for squamous-cell carcinoma of the anal canal: Analysis of patients from the national cancer data base","volume":"52","author":"Bilimoria","year":"2009","journal-title":"Dis Colon Rectum"},{"key":"key20200714083042_b30-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1615\/CritRevOncog.2014011922","article-title":"Regulation of the MAPK pathway by raf kinase inhibitory protein","volume":"19","author":"Vandamme","year":"2014","journal-title":"Crit Rev Oncog"},{"key":"key20200714083042_b31-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1186\/s13000-014-0221-9","article-title":"Different approaches for interpretation and reporting of immunohistochemistry analysis results in the bone tissue-a review","volume":"9","author":"Fedchenko","year":"2014","journal-title":"Diagn Pathol"},{"key":"key20200714083042_b32-ol-0-0-8828","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1177\/147323001103900125","article-title":"Immunohistochemical detection of Raf kinase inhibitor protein in normal cervical tissue and cervical cancer tissue","volume":"39","author":"Hu","year":"2011","journal-title":"J Int Med Res"}],"container-title":["Oncology Letters"],"original-title":[],"deposited":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T08:56:01Z","timestamp":1594716961000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/ol.2018.8828"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,30]]},"references-count":32,"URL":"https:\/\/doi.org\/10.3892\/ol.2018.8828","relation":{},"ISSN":["1792-1074","1792-1082"],"issn-type":[{"value":"1792-1074","type":"print"},{"value":"1792-1082","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,30]]}}}