{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T00:42:03Z","timestamp":1662424923173},"reference-count":29,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncol Lett"],"DOI":"10.3892\/ol.2018.9700","type":"journal-article","created":{"date-parts":[[2018,11,14]],"date-time":"2018-11-14T13:13:38Z","timestamp":1542201218000},"source":"Crossref","is-referenced-by-count":1,"title":["Alsterpaullone induces apoptosis of HepG2 cells via a p38 mitogen\u2011activated protein kinase signaling pathway"],"prefix":"10.3892","author":[{"given":"Peng","family":"Yin","sequence":"first","affiliation":[{"name":"Department of Organ Transplantation, Changzheng Hospital, Shanghai 200003, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nanxin","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Organ Transplantation, Changzheng Hospital, Shanghai 200003, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junfeng","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Organ Transplantation, Changzheng Hospital, Shanghai 200003, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunyang","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Organ Transplantation, Changzheng Hospital, Shanghai 200003, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaomei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Organ Transplantation, Changzheng Hospital, Shanghai 200003, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guoshan","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Organ Transplantation, Changzheng Hospital, Shanghai 200003, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2018,11,14]]},"reference":[{"key":"key20200714085053_b1-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"1331","DOI":"10.1016\/j.jpedsurg.2011.11.073","article-title":"Changing treatment and outcome of children with hepatoblastoma: Analysis of a single center experience over the last 20 years","volume":"47","author":"Ismail","year":"2012","journal-title":"J Pediatr Surg"},{"key":"key20200714085053_b2-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1097\/MOP.0000000000000046","article-title":"Hepatoblastoma state of the art: Pathology, genetics, risk stratification, and chemotherapy","volume":"26","author":"Czauderna","year":"2014","journal-title":"Curr Opin Pediatr"},{"key":"key20200714085053_b3-ol-0-0-9700","doi-asserted-by":"crossref","first-page":"520","DOI":"10.5858\/2007-131-520-PFTEOS","article-title":"College of American Pathologists: Protocol for the examination of specimens from pediatric patients with hepatoblastoma","volume":"131","author":"Finegold","year":"2007","journal-title":"Arch Pathol Lab Med"},{"key":"key20200714085053_b4-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1007\/s10024-005-1154-9","article-title":"Beckwith-Wiedemann syndrome: Historical, clinicopathological, and etiopathogenetic perspectives","volume":"8","author":"Cohen","year":"2005","journal-title":"Pediatr Dev Pathol"},{"key":"key20200714085053_b5-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"602091","DOI":"10.1155\/2013\/602091","article-title":"Alsterpaullone, a cyclin-dependent kinase inhibitor, mediated toxicity in HeLa cells through apoptosis-inducing effect","volume":"2013","author":"Cui","year":"2013","journal-title":"J Anal Methods Chem"},{"key":"key20200714085053_b6-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"2909","DOI":"10.1021\/jm9900570","article-title":"Paullones, a series of cyclin-dependent kinase inhibitors: Synthesis, evaluation of CDK1\/cyclin B inhibition, and in vitro antitumor activity","volume":"42","author":"Schultz","year":"1999","journal-title":"J Med Chem"},{"key":"key20200714085053_b7-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1016\/j.bpobgyn.2011.04.005","article-title":"Histology of cervical intraepithelial neoplasia and the role of biomarkers","volume":"25","author":"Martin","year":"2011","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"key20200714085053_b8-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1002\/mc.10114","article-title":"Alsterpaullone, a novel cyclin-dependent kinase inhibitor, induces apoptosis by activation of caspase-9 due to perturbation in mitochondrial membrane potential","volume":"36","author":"Lahusen","year":"2003","journal-title":"Mol Carcinog"},{"key":"key20200714085053_b9-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/j.cbi.2010.11.008","article-title":"Proliferative and androgenic effects of indirubin derivatives in LNCaP human prostate cancer cells at sub-apoptotic concentrations","volume":"189","author":"Rivest","year":"2011","journal-title":"Chem Biol Interact"},{"key":"key20200714085053_b10-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"349","DOI":"10.4161\/cc.3.3.680","article-title":"Inhibition of cdk1 by alsterpaullone and thioflavopiridol correlates with increased transit time from mid G2 through prophase","volume":"3","author":"Soni","year":"2004","journal-title":"Cell Cycle"},{"key":"key20200714085053_b11-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"21718","DOI":"10.18632\/oncotarget.4304","article-title":"Identification of alsterpaullone as a novel small molecule inhibitor to target group 3 medulloblastoma","volume":"6","author":"Faria","year":"2015","journal-title":"Oncotarget"},{"key":"key20200714085053_b12-ol-0-0-9700","first-page":"575","article-title":"Novel chemotherapy using histone deacetylase inhibitors in cervical cancer","volume":"12","author":"Takai","year":"2011","journal-title":"Asian Pac J Cancer Prev"},{"key":"key20200714085053_b13-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"8559","DOI":"10.1039\/c2cc33786j","article-title":"Ruthenium- and osmium-arene-based paullones bearing a TEMPO free-radical unit as potential anticancer drugs","volume":"48","author":"Arion","year":"2012","journal-title":"Chem Commun (Camb)"},{"key":"key20200714085053_b14-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1038\/nrd2199","article-title":"How many drug targets are there?","volume":"5","author":"Overington","year":"2006","journal-title":"Nat Rev Drug Discov"},{"key":"key20200714085053_b15-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1038\/nrd2132","article-title":"Drugs, their targets and the nature and number of drug targets","volume":"5","author":"Imming","year":"2006","journal-title":"Nat Rev Drug Discov"},{"key":"key20200714085053_b16-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1093\/nar\/28.1.235","article-title":"The protein data bank","volume":"28","author":"Berman","year":"2000","journal-title":"Nucleic Acids Res"},{"key":"key20200714085053_b17-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"2871","DOI":"10.3892\/or.2015.4325","article-title":"Phloretin induces apoptosis of non-small cell lung carcinoma A549 cells via JNK1\/2 and p38 MAPK pathways","volume":"34","author":"Min","year":"2015","journal-title":"Oncol Rep"},{"key":"key20200714085053_b18-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1007\/s10147-013-0616-8","article-title":"Current chemotherapeutic approaches for hepatoblastoma","volume":"18","author":"Watanabe","year":"2013","journal-title":"Int J Clin Oncol"},{"key":"key20200714085053_b19-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"3438","DOI":"10.1200\/JCO.2002.07.400","article-title":"Treatment of unresectable and metastatic hepatoblastoma: A pediatric oncology group phase II study","volume":"20","author":"Katzenstein","year":"2002","journal-title":"J Clin Oncol"},{"key":"key20200714085053_b20-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"1418","DOI":"10.1016\/S0959-8049(00)00074-5","article-title":"Pretreatment prognostic factors for children with hepatoblastoma-results from the International Society of Paediatric Oncology (SIOP) study SIOPEL 1","volume":"36","author":"Brown","year":"2000","journal-title":"Eur J Cancer"},{"key":"key20200714085053_b21-ol-0-0-9700","first-page":"255","article-title":"The ICE family of cysteine proteases as effectors of cell death","volume":"3","author":"Kumar","year":"1996","journal-title":"Cell Death Differ"},{"key":"key20200714085053_b22-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1016\/S0968-0004(97)01085-2","article-title":"Caspases: Killer proteases","volume":"22","author":"Nicholson","year":"1997","journal-title":"Trends Biochem Sci"},{"key":"key20200714085053_b23-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/0092-8674(94)90188-0","article-title":"Checkpoints of dueling dimers foil death wishes","volume":"79","author":"Oltvai","year":"1994","journal-title":"Cell"},{"key":"key20200714085053_b24-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1146\/annurev.biochem.69.1.217","article-title":"Apoptosis signaling","volume":"69","author":"Strasser","year":"2000","journal-title":"Annu Rev Biochem"},{"key":"key20200714085053_b25-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/S0092-8674(00)81334-3","article-title":"Human ICE\/CED-3 protease nomenclature","volume":"87","author":"Alnemri","year":"1996","journal-title":"Cell"},{"key":"key20200714085053_b26-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"1312","DOI":"10.1126\/science.281.5381.1312","article-title":"Caspases: Enemies within","volume":"281","author":"Thornberry","year":"1998","journal-title":"Science"},{"key":"key20200714085053_b27-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"513","DOI":"10.3892\/or.2013.2447","article-title":"MAPK inhibitors augment gallic acid-induced A549 lung cancer cell death through the enhancement of glutathione depletion","volume":"30","author":"Park","year":"2013","journal-title":"Oncol Rep"},{"key":"key20200714085053_b28-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1007\/s11010-014-2166-4","article-title":"Anticancer effect of calycopterin via PI3K\/Akt and MAPK signaling pathways, ROS-mediated pathway and mitochondrial dysfunction in hepatoblastoma cancer (HepG2) cells","volume":"397","author":"Esmaeili","year":"2014","journal-title":"Mol Cell Biochem"},{"key":"key20200714085053_b29-ol-0-0-9700","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.fct.2016.03.013","article-title":"Involvement of PI3K\/Akt, ERK and p38 signaling pathways in emodin-mediated extrinsic and intrinsic human hepatoblastoma cell apoptosis","volume":"92","author":"Cui","year":"2016","journal-title":"Food Chem Toxicol"}],"container-title":["Oncology Letters"],"original-title":[],"deposited":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T00:24:00Z","timestamp":1662423840000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/ol.2018.9700"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,14]]},"references-count":29,"URL":"https:\/\/doi.org\/10.3892\/ol.2018.9700","relation":{},"ISSN":["1792-1074","1792-1082"],"issn-type":[{"value":"1792-1074","type":"print"},{"value":"1792-1082","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,14]]}}}