{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T22:12:49Z","timestamp":1726179169935},"reference-count":51,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncol Lett"],"DOI":"10.3892\/ol.2019.10560","type":"journal-article","created":{"date-parts":[[2019,7,4]],"date-time":"2019-07-04T14:34:02Z","timestamp":1562250842000},"source":"Crossref","is-referenced-by-count":4,"title":["Detection and clinical significance of circulating tumor cells in patients with nasopharyngeal carcinoma"],"prefix":"10.3892","author":[{"given":"Zunbei","family":"Wen","sequence":"first","affiliation":[{"name":"Department of Radiotherapy, The People's Hospital of Gaozhou, Gaozhou, Guangdong 525200, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongtai","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, The People's Hospital of Gaozhou, Gaozhou, Guangdong 525200, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pangxiao","family":"Yong","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, The People's Hospital of Gaozhou, Gaozhou, Guangdong 525200, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dunbo","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, The People's Hospital of Gaozhou, Gaozhou, Guangdong 525200, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Di","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, The People's Hospital of Gaozhou, Gaozhou, Guangdong 525200, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haiwen","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, The People's Hospital of Gaozhou, Gaozhou, Guangdong 525200, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongying","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, The People's Hospital of Gaozhou, Gaozhou, Guangdong 525200, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiyang","family":"Wu","sequence":"additional","affiliation":[{"name":"SurExam Bio\u2011Tech, Guangzhou Technology Innovation Base, Guangzhou, Guangdong 510000, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cong","family":"Li","sequence":"additional","affiliation":[{"name":"SurExam Bio\u2011Tech, Guangzhou Technology Innovation Base, Guangzhou, Guangdong 510000, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen","family":"Cheng","sequence":"additional","affiliation":[{"name":"SurExam Bio\u2011Tech, Guangzhou Technology Innovation Base, Guangzhou, Guangdong 510000, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2019,7,4]]},"reference":[{"key":"key20200714091232_b1-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"114","DOI":"10.5732\/cjc.010.10377","article-title":"The prevalence and prevention of nasopharyngeal carcinoma in China","volume":"30","author":"Cao","year":"2011","journal-title":"Chin J Cancer"},{"key":"key20200714091232_b2-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"1160","DOI":"10.1038\/bjc.2011.38","article-title":"Epstein-Barr Virus latent membrane protein 1 induces Snail and epithelial-mesenchymal transition in metastatic nasopharyngeal carcinoma","volume":"104","author":"Horikawa","year":"2011","journal-title":"Br J Cancer"},{"key":"key20200714091232_b3-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"vii308","DOI":"10.1093\/annonc\/mdq277","article-title":"Nasopharyngeal carcinoma","volume":"21","author":"Chan","year":"2010","journal-title":"Ann Oncol"},{"key":"key20200714091232_b4-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"906","DOI":"10.1186\/s12885-015-1902-9","article-title":"Smoking and nasopharyngeal carcinoma mortality: A cohort study of 101,823 adults in Guangzhou, China","volume":"15","author":"Lin","year":"2015","journal-title":"BMC Cancer"},{"key":"key20200714091232_b5-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/j.imbio.2015.09.015","article-title":"Polymorphisms in host immune response associated genes and risk of nasopharyngeal carcinoma development in Portugal","volume":"221","author":"Sousa","year":"2016","journal-title":"Immunobiology"},{"key":"key20200714091232_b6-ol-0-0-10560","first-page":"146","article-title":"A case of cancer in which cells similar to those in the tumours were seen in the blood after death","volume":"14","author":"Ashworth","year":"1869","journal-title":"Aust Med J"},{"key":"key20200714091232_b7-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1016\/j.cell.2006.11.001","article-title":"Cancer metastasis: building a framework","volume":"127","author":"Gupta","year":"2006","journal-title":"Cell"},{"key":"key20200714091232_b8-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1159\/000337106","article-title":"Epithelial-mesenchymal transition: A hallmark in metastasis formation linking circulating tumor cells and cancer stem cells","volume":"79","author":"Ksi\u0105\u017ckiewicz","year":"2012","journal-title":"Pathobiology"},{"key":"key20200714091232_b9-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"2153","DOI":"10.1016\/j.biocel.2007.07.011","article-title":"Epithelial-mesenchymal transition and tumour invasion","volume":"39","author":"Guarino","year":"2007","journal-title":"Int J Biochem Cell Biol"},{"key":"key20200714091232_b10-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"1338","DOI":"10.1038\/bjc.2011.405","article-title":"Detection of circulating tumour cells with a hybrid (epithelial\/mesenchymal) phenotype in patients with metastatic non-small cell lung cancer","volume":"105","author":"Lecharpentier","year":"2011","journal-title":"Br J Cancer"},{"key":"key20200714091232_b11-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1080\/14737159.2017.1275572","article-title":"Classifying circulating tumor cells to monitor cancer progression","volume":"17","author":"Economopoulou","year":"2017","journal-title":"Expert Rev Mol Diagn"},{"key":"key20200714091232_b12-ol-0-0-10560","doi-asserted-by":"crossref","first-page":"965","DOI":"10.2174\/1389450115666140902125150","article-title":"Circulating tumor cells (CTCs) as a liquid biopsy material and drug target","volume":"15","author":"Cai","year":"2014","journal-title":"Curr Drug Targets"},{"key":"key20200714091232_b13-ol-0-0-10560","first-page":"S9","article-title":"Circulating tumor cells, disease progression, and survival in metastatic breast cancer","author":"Cristofanilli","year":"2006","journal-title":"Semin Oncol 33 (3 Suppl 9)"},{"key":"key20200714091232_b14-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1093\/annonc\/mdm558","article-title":"Variation of circulating tumor cell levels during treatment of metastatic breast cancer: Prognostic and therapeutic implications","volume":"19","author":"Nol\u00e9","year":"2008","journal-title":"Ann Oncol"},{"key":"key20200714091232_b15-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"3213","DOI":"10.1200\/JCO.2007.15.8923","article-title":"Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer","volume":"26","author":"Cohen","year":"2008","journal-title":"J Clin Oncol"},{"key":"key20200714091232_b16-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"395","DOI":"10.3233\/BLC-160069","article-title":"Clinical significance of early changes in circulating tumor cells from patients receiving first-line cisplatin-based chemotherapy for metastatic urothelial carcinoma","volume":"2","author":"Fina","year":"2016","journal-title":"Bladder Cancer"},{"key":"key20200714091232_b17-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"e21020","DOI":"10.1200\/jco.2011.29.15_suppl.e21020","article-title":"Circulating tumor cells as a predictive marker for chemotherapy and prognostic marker in patients with metastatic non-small cell lung cancer","volume":"29","author":"Hirose","year":"2011","journal-title":"J Clin Oncol"},{"key":"key20200714091232_b18-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1615\/CritRevOncog.2016016120","article-title":"Circulating tumor cells in breast cancer patients","volume":"21","author":"Hall","year":"2016","journal-title":"Crit Rev Oncog"},{"key":"key20200714091232_b19-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1016\/j.juro.2015.02.2951","article-title":"Circulating tumor cells as potential biomarkers in bladder cancer","volume":"194","author":"Alva","year":"2015","journal-title":"J Urol"},{"key":"key20200714091232_b20-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1387\/ijdb.041793ld","article-title":"N-cadherin in the spotlight of cell-cell adhesion, differentiation, embryogenesis, invasion and signalling","volume":"48","author":"Derycke","year":"2004","journal-title":"Int J Dev Bio"},{"key":"key20200714091232_b21-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1158\/0008-5472.CAN-10-2301","article-title":"Cancer cells cut homophilic cell adhesion molecules and run","volume":"71","author":"Craig","year":"2011","journal-title":"Cancer Res"},{"key":"key20200714091232_b22-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1083\/jcb.147.3.631","article-title":"N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression","volume":"147","author":"Nieman","year":"1999","journal-title":"J Cell Biol"},{"key":"key20200714091232_b23-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"1885","DOI":"10.1038\/bjc.2011.452","article-title":"E\/N-cadherin switch mediates cancer progression via TGF-\u03b2-induced epithelial-to-mesenchymal transition in extrahepatic cholangiocarcinoma","volume":"105","author":"Araki","year":"2011","journal-title":"Br J Cancer"},{"key":"key20200714091232_b24-ol-0-0-10560","first-page":"365","article-title":"Effects of N-cadherin expression on cell cycle, cell apoptosis and invasiveness and metastasis of tongue squamous cell carcinoma cell line Tca8113 cells","volume":"46","author":"Li","year":"2011","journal-title":"Zhonghua Kou Qiang Yi Xue Za Zhi"},{"key":"key20200714091232_b25-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1083\/jcb.148.4.779","article-title":"Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis","volume":"148","author":"Hazan","year":"2000","journal-title":"J Cell Biol"},{"key":"key20200714091232_b26-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"2050","DOI":"10.3390\/cancers3022050","article-title":"Wnt\/\u03b2-catenin signaling in normal and cancer stem cells","volume":"3","author":"Valkenburg","year":"2011","journal-title":"Cancers (Basel)"},{"key":"key20200714091232_b27-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1038\/aps.2013.27","article-title":"Understanding and targeting cancer stem cells: Therapeutic implications and challenges","volume":"34","author":"Chen","year":"2013","journal-title":"Acta Pharmacol Sin"},{"key":"key20200714091232_b28-ol-0-0-10560","first-page":"384","article-title":"Role of Wnt\/\u03b2-catenin pathway in differentiation of nasopharyngeal carcinoma","volume":"4","author":"Lin","year":"2005","journal-title":"J Sun Yat-sen Univ (Med Sci)"},{"key":"key20200714091232_b29-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1515\/cclm-2013-0558","article-title":"Enrichment and enumeration of circulating tumor cells by efficient depletion of leukocyte fractions","volume":"52","author":"Wu","year":"2014","journal-title":"Clin Chem Lab Med"},{"key":"key20200714091232_b30-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"e0123976","DOI":"10.1371\/journal.pone.0123976","article-title":"Classification of circulating tumor cells by epithelial-mesenchymal transition markers","volume":"10","author":"Wu","year":"2015","journal-title":"PLoS One"},{"key":"key20200714091232_b31-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1309\/90BU6KDXANFLN4RJ","article-title":"Branched DNA technology in molecular diagnostics","volume":"126","author":"Tsongalis","year":"2006","journal-title":"Am J Clin Pathol"},{"key":"key20200714091232_b32-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"4842","DOI":"10.1093\/nar\/25.23.4842","article-title":"Chemical synthesis and characterization of branched oligodeoxyribonucleotides (bDNA) for use as signal amplifiers in nucleic acid quantification assays","volume":"25","author":"Horn","year":"1997","journal-title":"Nucleic Acids Res"},{"key":"key20200714091232_b33-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"vii308","DOI":"10.1093\/annonc\/mdq277","article-title":"Nasopharyngeal carcinoma","volume":"21","author":"Chan","year":"2010","journal-title":"Ann Oncol"},{"key":"key20200714091232_b34-ol-0-0-10560","first-page":"1141","article-title":"Histopathological classification of nasopharyngeal carcinoma","volume":"12","author":"Wei","year":"2011","journal-title":"Asian Pac J Cancer Prev"},{"key":"key20200714091232_b35-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"1280","DOI":"10.1093\/annonc\/mdq629","article-title":"Hemorrhagic complications in a phase ii study of sunitinib in patients of nasopharyngeal carcinoma who has previously received high-dose radiation","volume":"22","author":"Hui","year":"2011","journal-title":"Ann Oncol"},{"key":"key20200714091232_b36-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1111\/j.1365-2559.2012.04212.x","article-title":"Nuclear expression of N-cadherin correlates with poor prognosis of nasopharyngeal carcinoma","volume":"61","author":"Luo","year":"2012","journal-title":"Histopathology"},{"key":"key20200714091232_b37-ol-0-0-10560","first-page":"252","article-title":"Research of the relationship between \u03b2-catenin and c-myc-mediated Wnt pathway and laterally spreading tumors occurrence","volume":"21","author":"Shi","year":"2017","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"key20200714091232_b38-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"2987","DOI":"10.1038\/bjc.2013.659","article-title":"Comparison of TNM staging systems for nasopharyngeal carcinoma, and proposal of a new staging system","volume":"109","author":"OuYang","year":"2013","journal-title":"Br J Cancer"},{"key":"key20200714091232_b39-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1177\/1758834009360519","article-title":"Predictive and prognostic molecular markers for cancer medicine","volume":"2","author":"Mehta","year":"2010","journal-title":"Ther Adv Med Oncol"},{"key":"key20200714091232_b40-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1002\/1878-0261.12081","article-title":"Cancer metastasis through the prism of epithelial-to-mesenchymal transition in circulating tumor cells","volume":"11","author":"Micalizzi","year":"2017","journal-title":"Mol Oncol"},{"key":"key20200714091232_b41-ol-0-0-10560","first-page":"60","article-title":"The circulating tumor cells: Liquid biopsy of cancer","author":"Alix-Panabieres","year":"2014","journal-title":"Klin Lab Diagn"},{"key":"key20200714091232_b42-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1093\/jjco\/hyw046","article-title":"Distribution and clinical significance of circulating tumor cells in nasopharyngeal carcinoma","volume":"46","author":"Si","year":"2016","journal-title":"Jpn J Clin Oncol"},{"key":"key20200714091232_b43-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1007\/BF03014410","article-title":"The impact of radiotherapy course length on the treatment results of nasopharyngeal carcinoma (NPC)","volume":"7","author":"Chen","year":"1995","journal-title":"Chin J Cancer Res"},{"key":"key20200714091232_b44-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"256","DOI":"10.3109\/09553002.2014.873558","article-title":"Acute oral mucositis in nasopharyngeal carcinoma patients treated with radiotherapy: association with genetic polymorphism in DNA DSB repair genes","volume":"90","author":"Ren","year":"2014","journal-title":"Int J Radiat Biol"},{"key":"key20200714091232_b45-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1007\/s00066-003-1048-6","article-title":"Reirradiation of locally recurrent nasopharyngeal carcinoma","volume":"179","author":"Lengyel","year":"2003","journal-title":"Strahlenther Onkol"},{"key":"key20200714091232_b46-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"e91362","DOI":"10.1371\/journal.pone.0091362","article-title":"Effectiveness and toxicities of intensity-modulated radiation therapy for patients with T4 nasopharyngeal carcinoma","volume":"9","author":"Kong","year":"2014","journal-title":"PLoS One"},{"key":"key20200714091232_b47-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1016\/j.canlet.2006.12.014","article-title":"Circulating tumor cells (CTC) detection: Clinical impact and future directions","volume":"253","author":"Paterlini-Brechot","year":"2007","journal-title":"Cancer Lett"},{"key":"key20200714091232_b48-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1083\/jcb.106.3.873","article-title":"Cloning and expression of cDNA encoding a neural calcium-dependent cell adhesion molecule: Its identity in the cadherin gene family","volume":"106","author":"Hatta","year":"1988","journal-title":"J Cell Biol"},{"key":"key20200714091232_b49-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1007\/s10911-010-9178-9","article-title":"Epithelial-mesenchymal transition in cancer: Parallels between normal development and tumor progression","volume":"15","author":"Micalizzi","year":"2010","journal-title":"J Mammary Gland Biol Neoplasia"},{"key":"key20200714091232_b50-ol-0-0-10560","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1111\/j.1349-7006.2009.01419.x","article-title":"Epithelial-mesenchymal transition in cancer development and its clinical significance","volume":"101","author":"Iwatsuki","year":"2010","journal-title":"Cancer Sci"},{"key":"key20200714091232_b51-ol-0-0-10560","first-page":"1037","article-title":"The cadherin switch assessment in the epithelial-mesenchymal transition of urothelial bladder carcinomas","volume":"57","author":"Droca\u015f","year":"2016","journal-title":"Rom J Morphol Embryol"}],"container-title":["Oncology Letters"],"original-title":[],"deposited":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T09:54:21Z","timestamp":1594720461000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/ol.2019.10560"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,4]]},"references-count":51,"URL":"https:\/\/doi.org\/10.3892\/ol.2019.10560","relation":{},"ISSN":["1792-1074","1792-1082"],"issn-type":[{"value":"1792-1074","type":"print"},{"value":"1792-1082","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,4]]}}}