{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T13:43:50Z","timestamp":1759412630036},"reference-count":103,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncol Lett"],"DOI":"10.3892\/ol.2019.10713","type":"journal-article","created":{"date-parts":[[2019,8,5]],"date-time":"2019-08-05T11:32:19Z","timestamp":1565004739000},"source":"Crossref","is-referenced-by-count":3,"title":["Implication of viral microRNAs in the genesis and diagnosis of Epstein\u2011Barr virus\u2011associated tumors (Review)"],"prefix":"10.3892","author":[{"given":"Xiangning","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Pathophysiology, Chinese\u2011American Collaborative Cancer Institute, Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Guangdong Medical University, Dongguan, Guangdong 523808, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yudong","family":"Ye","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Dongguan City People's Hospital, Dongguan, Guangdong 523059, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Dongguan City People's Hospital, Dongguan, Guangdong 523059, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Biying","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology, College of Laboratory Medicine, Guangdong Medical University, Dongguan, Guangdong 523808, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qianhui","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Pearl River Hospital, Southern Medical University, Guangzhou, Guangdong 510280, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zunnan","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Pathophysiology, Chinese\u2011American Collaborative Cancer Institute, Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Guangdong Medical University, Dongguan, Guangdong 523808, P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2019,8,5]]},"reference":[{"key":"key20200714091512_b1-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1146\/annurev.pathol.1.110304.100209","article-title":"Spectrum of Epstein Barr virus associated diseases","volume":"1","author":"Kutok","year":"2006","journal-title":"Annu Rev Pathol"},{"key":"key20200714091512_b2-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"862","DOI":"10.1182\/blood-2005-07-2702","article-title":"Epstein-Barr virus: The impact of scientific advances on clinical practice","volume":"107","author":"Williams","year":"2006","journal-title":"Blood"},{"key":"key20200714091512_b3-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1016\/S1535-6108(04)00119-9","article-title":"Focus on nasopharyngeal carcinoma","volume":"5","author":"Lo","year":"2004","journal-title":"Cancer Cell"},{"key":"key20200714091512_b4-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.canlet.2011.03.003","article-title":"Gammaherpesvirus and lymphoproliferative disorders in immunocompromised patients","volume":"305","author":"Cesarman","year":"2011","journal-title":"Cancer Lett"},{"key":"key20200714091512_b5-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1126\/science.7725102","article-title":"Masking of the CBF1\/RBPJ kappa transcriptional repression domain by Epstein-Barr virus EBNA2","volume":"268","author":"Hsieh","year":"1995","journal-title":"Science"},{"key":"key20200714091512_b6-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.canlet.2013.05.018","article-title":"Pathogenic role of Epstein-Barr virus latent membrane protein-1 in the development of nasopharyngeal carcinoma","volume":"337","author":"Yoshizaki","year":"2013","journal-title":"Cancer Lett"},{"key":"key20200714091512_b7-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"3813","DOI":"10.1182\/blood-2007-03-080309","article-title":"EBV LMP2A affects LMP1-mediated NF-kappaB signaling and survival of lymphoma cells by regulating TRAF2 expression","volume":"111","author":"Guasparri","year":"2008","journal-title":"Blood"},{"key":"key20200714091512_b8-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"11256","DOI":"10.1128\/JVI.01492-15","article-title":"Host gene expression is regulated by two types of noncoding RNAs transcribed from the Epstein-Barr virus BamHI A rightward transcript region","volume":"89","author":"Marquitz","year":"2015","journal-title":"J Virol"},{"key":"key20200714091512_b9-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.cell.2009.01.002","article-title":"MicroRNAs: Target recognition and regulatory functions","volume":"136","author":"Bartel","year":"2009","journal-title":"Cell"},{"key":"key20200714091512_b10-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1038\/ncb0309-228","article-title":"Many roads to maturity: microRNA biogenesis pathways and their regulation","volume":"11","author":"Winter","year":"2009","journal-title":"Nat Cell Biol"},{"key":"key20200714091512_b11-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1016\/j.cell.2006.03.043","article-title":"Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex","volume":"125","author":"Han","year":"2006","journal-title":"Cell"},{"key":"key20200714091512_b12-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1016\/j.tim.2004.06.005","article-title":"EBV-associated nasopharyngeal carcinomas: From epidemiology to virus-targeting strategies","volume":"12","author":"Busson","year":"2004","journal-title":"Trends Microbiol"},{"key":"key20200714091512_b13-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1126\/science.1096781","article-title":"Identification of virus-encoded microRNAs","volume":"304","author":"Pfeffer","year":"2004","journal-title":"Science"},{"key":"key20200714091512_b14-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"3333","DOI":"10.1128\/JVI.01689-08","article-title":"Identification of novel Epstein-Barr virus microRNA genes from nasopharyngeal carcinomas","volume":"83","author":"Zhu","year":"2009","journal-title":"J Virol"},{"key":"key20200714091512_b15-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"9094","DOI":"10.1128\/JVI.00785-08","article-title":"Epstein-Barr virus BART microRNAs are produced from a large intron prior to splicing","volume":"82","author":"Edwards","year":"2008","journal-title":"J Virol"},{"key":"key20200714091512_b16-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"e1002193","DOI":"10.1371\/journal.ppat.1002193","article-title":"A novel persistence associated EBV miRNA expression profile is disrupted in neoplasia","volume":"7","author":"Qiu","year":"2011","journal-title":"PLoS Pathog"},{"key":"key20200714091512_b17-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1111\/jgh.13432","article-title":"Comprehensive profiling of virus microRNAs of Epstein-Barr virus-associated gastric carcinoma: Highlighting the interactions of ebv-Bart9 and host tumor cells","volume":"32","author":"Tsai","year":"2017","journal-title":"J Gastroenterol Hepatol"},{"key":"key20200714091512_b18-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1002\/cam4.1006","article-title":"Next-generation sequencing of miRNAs in clinical samples of Epstein-Barr virus-associated B-cell lymphomas","volume":"6","author":"Sakamoto","year":"2017","journal-title":"Cancer Med"},{"key":"key20200714091512_b19-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1002\/path.4025","article-title":"The pathological roles of BART miRNAs in nasopharyngeal carcinoma","volume":"227","author":"Lo","year":"2012","journal-title":"J Pathol"},{"key":"key20200714091512_b20-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1038\/310207a0","article-title":"DNA sequence and expression of the B95-8 Epstein-Barr virus genome","volume":"310","author":"Baer","year":"1984","journal-title":"Nature"},{"key":"key20200714091512_b21-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/j.virol.2009.01.006","article-title":"The microRNAs of Epstein-Barr Virus are expressed at dramatically differing levels among cell lines","volume":"386","author":"Pratt","year":"2009","journal-title":"Virology"},{"key":"key20200714091512_b22-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"1436","DOI":"10.1158\/0008-5472.CAN-07-5126","article-title":"EBV microRNAs in primary lymphomas and targeting of CXCL-11 by ebv-mir-BHRF1-3","volume":"68","author":"Xia","year":"2008","journal-title":"Cancer Res"},{"key":"key20200714091512_b23-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.1128\/JVI.02271-06","article-title":"Expression of viral microRNAs in Epstein-Barr virus-associated gastric carcinoma","volume":"81","author":"Kim","year":"2007","journal-title":"J Virol"},{"key":"key20200714091512_b24-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"2357","DOI":"10.1128\/JVI.02104-08","article-title":"Comprehensive profiling of Epstein-Barr virus microRNAs in nasopharyngeal carcinoma","volume":"83","author":"Cosmopoulos","year":"2009","journal-title":"J Virol"},{"issue":"pii","key":"key20200714091512_b25-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"e12745","DOI":"10.1371\/journal.pone.0012745","article-title":"Characterization of Epstein-Barr virus miRNAome in nasopharyngeal carcinoma by deep sequencing","volume":"5","author":"Chen","year":"2010","journal-title":"PLoS One"},{"key":"key20200714091512_b26-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"e42193","DOI":"10.1371\/journal.pone.0042193","article-title":"MicroRNA profiling of Epstein-Barr virus-associated NK\/T-cell lymphomas by deep sequencing","volume":"7","author":"Motsch","year":"2012","journal-title":"PLoS One"},{"key":"key20200714091512_b27-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1111\/j.1365-2141.2008.07186.x","article-title":"Viral microRNA profile in Epstein-Barr virus-associated peripheral T cell lymphoma","volume":"142","author":"Jun","year":"2008","journal-title":"Brit J Haematol"},{"key":"key20200714091512_b28-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1111\/j.1440-1827.1997.tb04450.x","article-title":"Epstein-Barr virus-positive multiple early gastric cancers and dysplastic lesions: A case report","volume":"47","author":"Arikawa","year":"1997","journal-title":"Pathol Int"},{"key":"key20200714091512_b29-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1111\/j.1440-1827.2010.02533.x","article-title":"Epstein-Barr virus and gastric carcinoma","volume":"60","author":"Fukayama","year":"2010","journal-title":"Pathol Int"},{"key":"key20200714091512_b30-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"698","DOI":"10.1002\/cncr.26309","article-title":"Profiling of Epstein-Barr virus-encoded microRNAs in nasopharyngeal carcinoma reveals potential biomarkers and oncomirs","volume":"118","author":"Wong","year":"2012","journal-title":"Cancer"},{"key":"key20200714091512_b31-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"e179","DOI":"10.1093\/nar\/gni178","article-title":"Real-time quantification of microRNAs by stem-loop RT-PCR","volume":"33","author":"Chen","year":"2005","journal-title":"Nucleic Acids Res"},{"key":"key20200714091512_b32-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"996","DOI":"10.1128\/JVI.01528-10","article-title":"Quantitative studies of Epstein-Barr virus-encoded microRNAs provide novel insights into their regulation","volume":"85","author":"Amoroso","year":"2011","journal-title":"J Virol"},{"key":"key20200714091512_b33-ol-0-0-10713","first-page":"3201","article-title":"Overexpression of Epstein-Barr virus-encoded microRNA-BART7 in undifferentiated nasopharyngeal carcinoma","volume":"32","author":"Chan","year":"2012","journal-title":"Anticancer Res"},{"key":"key20200714091512_b34-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"e23","DOI":"10.1371\/journal.ppat.0020023","article-title":"Epstein-Barr virus microRNAs are evolutionarily conserved and differentially expressed","volume":"2","author":"Cai","year":"2006","journal-title":"PLoS Pathog"},{"key":"key20200714091512_b35-ol-0-0-10713","first-page":"353","article-title":"Molecular genetics of DNA viruses: Recombinant virus technology","volume":"292","author":"Neuhierl","year":"2005","journal-title":"Methods Mol Biol"},{"key":"key20200714091512_b36-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"e1001294","DOI":"10.1371\/journal.ppat.1001294","article-title":"A viral microRNA cluster strongly potentiates the transforming properties of a human herpesvirus","volume":"7","author":"Feederle","year":"2011","journal-title":"PLoS Pathog"},{"issue":"pii","key":"key20200714091512_b37-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"20160270","DOI":"10.1098\/rstb.2016.0270","article-title":"Epstein-Barr virus infection and nasopharyngeal carcinoma","volume":"372","author":"Tsao","year":"2017","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"key20200714091512_b38-ol-0-0-10713","first-page":"581","article-title":"Epstein-Barr virus and nasopharyngeal carcinoma","volume":"33","author":"Young","year":"2014","journal-title":"Chin J Cancer"},{"issue":"pii","key":"key20200714091512_b39-ol-0-0-10713","first-page":"e01022","article-title":"Epstein-Barr virus MicroRNA miR-BART5-3p inhibits p53 expression","volume":"92","author":"Zheng","year":"2018","journal-title":"J Virol"},{"key":"key20200714091512_b40-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1016\/j.virol.2011.01.028","article-title":"The Epstein-Barr virus BART microRNAs target the pro-apoptotic protein Bim","volume":"412","author":"Marquitz","year":"2011","journal-title":"Virology"},{"key":"key20200714091512_b41-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"2551","DOI":"10.1084\/jem.20072581","article-title":"An Epstein-Barr virus-encoded microRNA targets PUMA to promote host cell survival","volume":"205","author":"Choy","year":"2008","journal-title":"J Exp Med"},{"key":"key20200714091512_b42-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1002\/ijc.28007","article-title":"Targeting of DICE1 tumor suppressor by Epstein-Barr virus-encoded miR-BART3* microRNA in nasopharyngeal carcinoma","volume":"133","author":"Lei","year":"2013","journal-title":"Int J Cancer"},{"key":"key20200714091512_b43-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"7353","DOI":"10.1038\/ncomms8353","article-title":"Epstein-Barr virus-encoded microRNA BART1 induces tumour metastasis by regulating PTEN-dependent pathways in nasopharyngeal carcinoma","volume":"6","author":"Cai","year":"2015","journal-title":"Nat Commun"},{"key":"key20200714091512_b44-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"2156","DOI":"10.1038\/onc.2014.341","article-title":"EBV-miR-BART7-3p promotes the EMT and metastasis of nasopharyngeal carcinoma cells by suppressing the tumor suppressor PTEN","volume":"34","author":"Cai","year":"2015","journal-title":"Oncogene"},{"key":"key20200714091512_b45-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"e1003974","DOI":"10.1371\/journal.ppat.1003974","article-title":"The Epstein-Barr virus-encoded microRNA MiR-BART9 promotes tumor metastasis by targeting E-cadherin in nasopharyngeal carcinoma","volume":"10","author":"Hsu","year":"2014","journal-title":"PLoS Pathog"},{"key":"key20200714091512_b46-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1016\/j.chom.2010.03.008","article-title":"Systematic analysis of viral and cellular microRNA targets in cells latently infected with human gamma-herpesviruses by RISC immunoprecipitation assay","volume":"7","author":"D\u00f6lken","year":"2010","journal-title":"Cell Host Microbe"},{"key":"key20200714091512_b47-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"33358","DOI":"10.1074\/jbc.M110.138362","article-title":"Editing of Epstein-Barr virus-encoded BART6 microRNAs controls their dicer targeting and consequently affects viral latency","volume":"285","author":"Iizasa","year":"2010","journal-title":"J Biol Chem"},{"key":"key20200714091512_b48-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1016\/j.chom.2009.03.003","article-title":"Diverse herpesvirus microRNAs target the stress-induced immune ligand MICB to escape recognition by natural killer cells","volume":"5","author":"Nachmani","year":"2009","journal-title":"Cell Host Microbe"},{"key":"key20200714091512_b49-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"16164","DOI":"10.1073\/pnas.0702896104","article-title":"Modulation of LMP1 protein expression by EBV-encoded microRNAs","volume":"104","author":"Lo","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20200714091512_b50-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"1174","DOI":"10.1593\/neo.09888","article-title":"Modulation of LMP2A expression by a newly identified Epstein-Barr virus-encoded microRNA miR-BART22","volume":"11","author":"Lung","year":"2009","journal-title":"Neoplasia"},{"key":"key20200714091512_b51-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1002\/jmv.22267","article-title":"Immune evasion strategies of the human gamma-herpesviruses: Implications for viral tumorigenesis","volume":"84","author":"Zhang","year":"2012","journal-title":"J Med Virol"},{"key":"key20200714091512_b52-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"e1001063","DOI":"10.1371\/journal.ppat.1001063","article-title":"Micro RNAs of Epstein-Barr virus promote cell cycle progression and prevent apoptosis of primary human B cells","volume":"6","author":"Seto","year":"2010","journal-title":"PLoS Pathog"},{"key":"key20200714091512_b53-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"1258","DOI":"10.1038\/onc.2013.71","article-title":"Epstein-Barr virus maintains lymphomas via its miRNAs","volume":"33","author":"Vereide","year":"2014","journal-title":"Oncogene"},{"key":"key20200714091512_b54-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"1687","DOI":"10.3390\/v4091687","article-title":"Emerging themes from EBV and KSHV microRNA targets","volume":"4","author":"Ramalingam","year":"2012","journal-title":"Viruses"},{"key":"key20200714091512_b55-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"257","DOI":"10.3389\/fonc.2018.00257","article-title":"Role of Epstein-Barr virus in the pathogenesis of head and neck cancers and its potential as an immunotherapeutic target","volume":"8","author":"Fernandes","year":"2018","journal-title":"Front in Oncol"},{"issue":"pii","key":"key20200714091512_b56-ol-0-0-10713","first-page":"e01667","article-title":"MicroRNAs of Epstein-Barr virus control innate and adaptive antiviral immunity","volume":"91","author":"Albanese","year":"2017","journal-title":"J Virol"},{"key":"key20200714091512_b57-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/j.virol.2017.09.015","article-title":"The Epstein-Barr virus miR-BHRF1 microRNAs regulate viral gene expression in cis","volume":"512","author":"Poling","year":"2017","journal-title":"Virology"},{"key":"key20200714091512_b58-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"e1002577","DOI":"10.1371\/journal.ppat.1002577","article-title":"Human cytomegalovirus clinical strain-specific microRNA miR-UL148D targets the human chemokine RANTES during infection","volume":"8","author":"Kim","year":"2012","journal-title":"PLoS Pathog"},{"key":"key20200714091512_b59-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"3795","DOI":"10.4049\/jimmunol.1200312","article-title":"Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1\u03b2 production","volume":"189","author":"Haneklaus","year":"2012","journal-title":"J Immunol"},{"key":"key20200714091512_b60-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"984","DOI":"10.1038\/ni.2097","article-title":"Human cytomegalovirus microRNA miR-US4-1 inhibits CD8(+) T cell responses by targeting the aminopeptidase ERAP1","volume":"12","author":"Kim","year":"2011","journal-title":"Nat Immunol"},{"key":"key20200714091512_b61-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.chom.2011.01.008","article-title":"An identical miRNA of the human JC and BK polyoma viruses targets the stress-induced ligand ULBP3 to escape immune elimination","volume":"9","author":"Bauman","year":"2011","journal-title":"Cell Host Microbe"},{"key":"key20200714091512_b62-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"11663","DOI":"10.1128\/JVI.01147-12","article-title":"Kaposi's sarcoma-associated herpesvirus microRNAs target IRAK1 and MYD88, two components of the toll-like receptor\/interleukin-1R signaling cascade, to reduce inflammatory-cytokine expression","volume":"86","author":"Abend","year":"2012","journal-title":"J Virol"},{"key":"key20200714091512_b63-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1038\/ncb0610-625b","article-title":"Regulation of NF-kappaB inhibitor IkappaBalpha and viral replication by a KSHV microRNA","volume":"12","author":"Lei","year":"2010","journal-title":"Nat Cell Biol"},{"key":"key20200714091512_b64-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1038\/cr.2011.5","article-title":"A human herpesvirus miRNA attenuates interferon signaling and contributes to maintenance of viral latency by targeting IKK\u03b5","volume":"21","author":"Liang","year":"2011","journal-title":"Cell Res"},{"key":"key20200714091512_b65-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"4062","DOI":"10.4049\/jimmunol.1501605","article-title":"EBV MicroRNA BART16 suppresses type I IFN signaling","volume":"198","author":"Hooykaas","year":"2017","journal-title":"J Immunol"},{"issue":"pii","key":"key20200714091512_b66-ol-0-0-10713","first-page":"e00530","article-title":"An Epstein-Barr virus microrna blocks interleukin-1 (IL-1) signaling by targeting IL-1 receptor 1","volume":"91","author":"Skinner","year":"2017","journal-title":"J Virol"},{"key":"key20200714091512_b67-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/978-3-319-39406-0_1","article-title":"Molecular cell biology of apoptosis and necroptosis in cancer","volume":"930","author":"Dillon","year":"2016","journal-title":"Adv Exp Med Biol"},{"issue":"pii","key":"key20200714091512_b68-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"E290","DOI":"10.3390\/v9100290","article-title":"The Bcl-2 family in host-virus interactions","volume":"9","author":"Kvansakul","year":"2017","journal-title":"Viruses"},{"key":"key20200714091512_b69-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"e1004979","DOI":"10.1371\/journal.ppat.1004979","article-title":"EBV BART microRNAs target multiple pro-apoptotic cellular genes to promote epithelial cell survival","volume":"11","author":"Kang","year":"2015","journal-title":"PLoS Pathog"},{"key":"key20200714091512_b70-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1016\/j.canlet.2014.10.023","article-title":"Epstein-Barr virus miR-BART20-5p regulates cell proliferation and apoptosis by targeting BAD","volume":"356","author":"Kim","year":"2015","journal-title":"Cancer Lett"},{"key":"key20200714091512_b71-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"1359","DOI":"10.1128\/JVI.02794-15","article-title":"Epstein-Barr virus MicroRNA miR-BART20-5p suppresses lytic induction by inhibiting BAD-mediated caspase-3-dependent apoptosis","volume":"90","author":"Kim","year":"2015","journal-title":"J Virol"},{"key":"key20200714091512_b72-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"9593","DOI":"10.1073\/pnas.1202910109","article-title":"Infection of Epstein-Barr virus in a gastric carcinoma cell line induces anchorage independence and global changes in gene expression","volume":"109","author":"Marquitz","year":"2012","journal-title":"Proc Natl Acad Sci USA"},{"key":"key20200714091512_b73-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"5581","DOI":"10.1128\/JVI.03639-14","article-title":"Profiling of virus-encoded microRNAs in Epstein-Barr virus-associated gastric carcinoma and their roles in gastric carcinogenesis","volume":"89","author":"Shinozaki-Ushiku","year":"2015","journal-title":"J Virol"},{"key":"key20200714091512_b74-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1186\/s12985-016-0602-7","article-title":"Epstein-Barr viral microRNAs target caspase 3","volume":"13","author":"Harold","year":"2016","journal-title":"Virol J"},{"key":"key20200714091512_b75-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1007\/s00705-016-3109-z","article-title":"TAX1BP1 downregulation by EBV-miR-BART15-3p enhances chemosensitivity of gastric cancer cells to 5-FU","volume":"162","author":"Choi","year":"2017","journal-title":"Arch Virol"},{"key":"key20200714091512_b76-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1038\/leu.2015.285","article-title":"EBV-miR-BHRF1-2 targets PRDM1\/Blimp1: Potential role in EBV lymphomagenesis","volume":"30","author":"Ma","year":"2016","journal-title":"Leukemia"},{"key":"key20200714091512_b77-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"e1005405","DOI":"10.1371\/journal.ppat.1005405","article-title":"A viral microRNA cluster regulates the expression of PTEN, p27 and of a bcl-2 homolog","volume":"12","author":"Bernhardt","year":"2016","journal-title":"PLoS Pathog"},{"key":"key20200714091512_b78-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1038\/nrg1879","article-title":"The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism","volume":"7","author":"Engelman","year":"2006","journal-title":"Nat Rev Genet"},{"key":"key20200714091512_b79-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"E301","DOI":"10.1002\/ijc.29206","article-title":"Circulating Epstein-Barr virus microRNAs miR-BART7 and miR-BART13 as biomarkers for nasopharyngeal carcinoma diagnosis and treatment","volume":"136","author":"Zhang","year":"2015","journal-title":"Int J Cancer"},{"key":"key20200714091512_b80-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1016\/j.ebiom.2015.04.018","article-title":"Epstein-Barr virus microRNAs are expressed in patients with chronic lymphocytic leukemia and correlate with overall survival","volume":"2","author":"Ferrajoli","year":"2015","journal-title":"EBioMedicine"},{"key":"key20200714091512_b81-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1289\/ehp.108-1638040","article-title":"Concentrations of organochlorines related to titers to Epstein-Barr virus early antigen IgG as risk factors for hairy cell leukemia","volume":"108","author":"Nordstr\u00f6m","year":"2000","journal-title":"Environ Health Perspect"},{"key":"key20200714091512_b82-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1586\/14737159.2014.944507","article-title":"Tissue slide-based microRNA characterization of tumors: How detailed could diagnosis become for cancer medicine?","volume":"14","author":"Sempere","year":"2014","journal-title":"Expert Rev Mol Diagn"},{"key":"key20200714091512_b83-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1186\/2050-7771-2-19","article-title":"MicroRNAs as promising biomarkers in cancer diagnostics","volume":"2","author":"Mishra","year":"2014","journal-title":"Biomark Res"},{"key":"key20200714091512_b84-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"e13247","DOI":"10.1371\/journal.pone.0013247","article-title":"Let-7 microRNA family is selectively secreted into the extracellular environment via exosomes in a metastatic gastric cancer cell line","volume":"5","author":"Ohshima","year":"2010","journal-title":"PLoS One"},{"key":"key20200714091512_b85-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"e13735","DOI":"10.1371\/journal.pone.0013735","article-title":"A pilot study of circulating miRNAs as potential biomarkers of early stage breast cancer","volume":"5","author":"Zhao","year":"2010","journal-title":"PLoS One"},{"key":"key20200714091512_b86-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"e13515","DOI":"10.1371\/journal.pone.0013515","article-title":"Selective release of microRNA species from normal and malignant mammary epithelial cells","volume":"5","author":"Pigati","year":"2010","journal-title":"PLoS One"},{"key":"key20200714091512_b87-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"4780","DOI":"10.1158\/1078-0432.CCR-12-2728","article-title":"Clinical significance and prognostic value of microRNA expression signatures in hepatocellular carcinoma","volume":"19","author":"Wei","year":"2013","journal-title":"Clin Cancer Res"},{"key":"key20200714091512_b88-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"e17745","DOI":"10.1371\/journal.pone.0017745","article-title":"Circulating plasma MiR-141 is a novel biomarker for metastatic colon cancer and predicts poor prognosis","volume":"6","author":"Cheng","year":"2011","journal-title":"PLoS One"},{"key":"key20200714091512_b89-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"2015","DOI":"10.1038\/sj.onc.1210836","article-title":"MicroRNA expression signature of human sarcomas","volume":"27","author":"Subramanian","year":"2008","journal-title":"Oncogene"},{"key":"key20200714091512_b90-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1080\/13547500802646572","article-title":"MicroRNAs as biomarkers and therapeutic drugs in human cancer","volume":"13","author":"Osaki","year":"2008","journal-title":"Biomarkers"},{"key":"key20200714091512_b91-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1093\/jnci\/djs027","article-title":"Clinical outcome prediction by microRNAs in human cancer: A systematic review","volume":"104","author":"Nair","year":"2012","journal-title":"J Natl Cancer Inst"},{"key":"key20200714091512_b92-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"1721","DOI":"10.1200\/JCO.2009.24.9342","article-title":"Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer","volume":"28","author":"Hu","year":"2010","journal-title":"J Clin Oncol"},{"key":"key20200714091512_b93-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1182\/blood-2011-01-330704","article-title":"Circulating microRNAs let-7a and miR-16 predict progression-free survival and overall survival in patients with myelodysplastic syndrome","volume":"118","author":"Zuo","year":"2011","journal-title":"Blood"},{"key":"key20200714091512_b94-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1038\/nrc1840","article-title":"Oncomirs-microRNAs with a role in cancer","volume":"6","author":"Esquela-Kerscher","year":"2006","journal-title":"Nat Rev Cancer"},{"key":"key20200714091512_b95-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"2587","DOI":"10.1016\/j.ejca.2015.08.006","article-title":"Intensity-modulated radiotherapy prolongs the survival of patients with nasopharyngeal carcinoma compared with conventional two-dimensional radiotherapy: A 10-year experience with a large cohort and long follow-up","volume":"51","author":"Zhang","year":"2015","journal-title":"Eur J Cancer"},{"key":"key20200714091512_b96-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1186\/1471-2407-14-348","article-title":"Matrix metalloproteinase 12 is induced by heterogeneous nuclear ribonucleoprotein K and promotes migration and invasion in nasopharyngeal carcinoma","volume":"14","author":"Chung","year":"2014","journal-title":"BMC Cancer"},{"key":"key20200714091512_b97-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"789","DOI":"10.3892\/mco.2014.315","article-title":"A risk score model for the metastasis of level Ib lymph node based on the clinicopathological features of nasopharyngeal carcinoma in a large sample","volume":"2","author":"Yi","year":"2014","journal-title":"Mol Clin Oncol"},{"key":"key20200714091512_b98-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/1748-717X-9-7","article-title":"Involvement of both cervical lymph nodes and retropharyngeal lymph nodes has prognostic value for N1 patients with nasopharyngeal carcinoma","volume":"9","author":"Shi","year":"2014","journal-title":"Radiat Oncol"},{"key":"key20200714091512_b99-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1186\/s13014-016-0691-x","article-title":"High-risk factors of parotid lymph node metastasis in nasopharyngeal carcinoma: A case-control study","volume":"11","author":"Wang","year":"2016","journal-title":"Radiat Oncol"},{"key":"key20200714091512_b100-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.oraloncology.2017.03.010","article-title":"The feasibility of contralateral lower neck sparing intensity modulation radiated therapy for nasopharyngeal carcinoma patients with unilateral cervical lymph node involvement","volume":"69","author":"Tang","year":"2017","journal-title":"Oral Oncol"},{"key":"key20200714091512_b101-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"13919","DOI":"10.1038\/srep13919","article-title":"Prognostic value of parotid lymph node metastasis in patients with nasopharyngeal carcinoma receiving intensity-modulated radiotherapy","volume":"5","author":"Zhang","year":"2015","journal-title":"Sci Rep"},{"key":"key20200714091512_b102-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"2065","DOI":"10.1084\/jem.20160248","article-title":"Epstein-Barr viral miRNAs inhibit antiviral CD4+ T cell responses targeting IL-12 and peptide processing","volume":"213","author":"Tagawa","year":"2016","journal-title":"J Exp Med"},{"key":"key20200714091512_b103-ol-0-0-10713","doi-asserted-by":"publisher","first-page":"9801","DOI":"10.1128\/JVI.05100-11","article-title":"The members of an Epstein-Barr virus microRNA cluster cooperate to transform B lymphocytes","volume":"85","author":"Feederle","year":"2011","journal-title":"J Virol"}],"container-title":["Oncology Letters"],"original-title":[],"deposited":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T09:55:24Z","timestamp":1594720524000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/ol.2019.10713"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,5]]},"references-count":103,"URL":"https:\/\/doi.org\/10.3892\/ol.2019.10713","relation":{},"ISSN":["1792-1074","1792-1082"],"issn-type":[{"value":"1792-1074","type":"print"},{"value":"1792-1082","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,5]]}}}