{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T12:42:39Z","timestamp":1784119359886,"version":"3.55.0"},"reference-count":40,"publisher":"Spandidos Publications","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncol Lett"],"DOI":"10.3892\/ol.2019.10850","type":"journal-article","created":{"date-parts":[[2019,9,11]],"date-time":"2019-09-11T09:47:35Z","timestamp":1568195255000},"source":"Crossref","is-referenced-by-count":8,"title":["Exosome complex genes mediate RNA degradation and predict survival in mantle cell lymphoma"],"prefix":"10.3892","author":[{"given":"Weilong","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Hematology, Lymphoma Research Center, Peking University Third Hospital, Beijing 100191, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junyong","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing 100853, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"He","sequence":"additional","affiliation":[{"name":"Department of Pathology, Beijing Tiantan Hospital Affiliated with Capital Medical University, Beijing 100050, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoni","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, The First Affiliated Hospital of Gannan Medical University, Ganzhou, Guangdong 341000, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinhang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pathology, Chinese People's Liberation Army General Hospital, Beijing 100853, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Hematology, Lymphoma Research Center, Peking University Third Hospital, Beijing 100191, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Hematology, Lymphoma Research Center, Peking University Third Hospital, Beijing 100191, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Hematology, Lymphoma Research Center, Peking University Third Hospital, Beijing 100191, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Hematology, Lymphoma Research Center, Peking University Third Hospital, Beijing 100191, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuru","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pathology, Beijing Tiantan Hospital Affiliated with Capital Medical University, Beijing 100050, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiru","family":"Li","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing 100853, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongmei","family":"Jing","sequence":"additional","affiliation":[{"name":"Department of Hematology, Lymphoma Research Center, Peking University Third Hospital, Beijing 100191, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2019,9,11]]},"reference":[{"key":"key20200714091949_b1-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1016\/j.cell.2009.01.019","article-title":"The many pathways of RNA degradation","volume":"136","author":"Houseley","year":"2009","journal-title":"Cell"},{"key":"key20200714091949_b2-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1038\/35067025","article-title":"The cap-to-tail guide to mRNA turnover","volume":"2","author":"Wilusz","year":"2001","journal-title":"Nat Rev Mol Cell Biol"},{"key":"key20200714091949_b3-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"1315","DOI":"10.1101\/gr.2122004","article-title":"A Protein Interaction Framework for Human mRNA Degradation","volume":"14","author":"Lehner","year":"2004","journal-title":"Genome Res"},{"key":"key20200714091949_b4-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1016\/S0092-8674(01)00592-X","article-title":"Functional link between the mammalian exosome and mRNA decapping","volume":"107","author":"Wang","year":"2001","journal-title":"Cell"},{"key":"key20200714091949_b5-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1016\/S0092-8674(01)00578-5","article-title":"AU binding proteins recruit the exosome to degrade ARE-containing mRNAs","volume":"107","author":"Chen","year":"2001","journal-title":"Cell"},{"key":"key20200714091949_b6-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/S0074-7696(06)51005-8","article-title":"Cell and molecular biology of the exosome: How to make or break an RNA","volume":"251","author":"Schilders","year":"2006","journal-title":"Int Rev Cytol"},{"key":"key20200714091949_b7-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.1261\/rna.575107","article-title":"Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways","volume":"13","author":"van Dijk","year":"2007","journal-title":"RNA"},{"key":"key20200714091949_b8-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"1810","DOI":"10.1261\/rna.144606","article-title":"Sequence-specific RNA binding mediated by the RNase PH domain of components of the exosome","volume":"12","author":"Anderson","year":"2006","journal-title":"RNA"},{"key":"key20200714091949_b9-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1016\/S1097-2765(03)00349-6","article-title":"Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities","volume":"12","author":"Lejeune","year":"2003","journal-title":"Mol Cell"},{"key":"key20200714091949_b10-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1038\/nature23883","article-title":"m6 A modulates haematopoietic stem and progenitor cell specification","volume":"549","author":"Zhang","year":"2017","journal-title":"Nature"},{"key":"key20200714091949_b11-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1038\/nature23450","article-title":"m6 A mRNA methylation controls T cell homeostasis by targeting the IL-7\/STAT5\/SOCS pathways","volume":"548","author":"Li","year":"2017","journal-title":"Nature"},{"key":"key20200714091949_b12-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1023\/A:1008265532487","article-title":"Epidemiology of the non-Hodgkin's lymphomas: Distributions of the major subtypes differ by geographic locations. Non-hodgkin's lymphoma classification project","volume":"9","author":"Anderson","year":"1998","journal-title":"Ann Oncol"},{"key":"key20200714091949_b13-ol-0-0-10850","first-page":"44","article-title":"Mantle cell lymphoma: State of the art","volume":"13","author":"Skarbnik","year":"2015","journal-title":"Clin Adv Hematol Oncol"},{"key":"key20200714091949_b14-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1002\/cncr.23608","article-title":"Incidence trends of mantle cell lymphoma in the United States between 1992 and 2004","volume":"113","author":"Zhou","year":"2008","journal-title":"Cancer"},{"key":"key20200714091949_b15-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"1469","DOI":"10.1182\/blood-2009-02-179739","article-title":"How I treat mantle cell lymphoma","volume":"114","author":"Ghielmini","year":"2009","journal-title":"Blood"},{"key":"key20200714091949_b16-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1182\/asheducation-2009.1.542","article-title":"Current treatment standards and emerging strategies in mantle cell lymphoma","author":"Dreyling","year":"2009","journal-title":"Hematology Am Soc Hematol Educ Program"},{"key":"key20200714091949_b17-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1093\/oxfordjournals.annonc.a058904","article-title":"European lymphoma task force (ELTF): Report of the workshop on mantle cell lymphoma (MCL)","volume":"5","author":"Zucca","year":"1994","journal-title":"Ann Oncol"},{"key":"key20200714091949_b18-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1097\/00000478-199207000-00001","article-title":"Mantle cell lymphoma. A proposal for unification of morphologic, immunologic, and molecular data","volume":"16","author":"Banks","year":"1992","journal-title":"Am J Surg Pathol"},{"key":"key20200714091949_b19-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1177\/2040620714561579","article-title":"Mantle cell lymphoma: Observation to transplantation","volume":"6","author":"Rajabi","year":"2015","journal-title":"Ther Adv Hematol"},{"key":"key20200714091949_b20-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1200\/JCO.2008.16.8435","article-title":"Improvement of overall survival in advanced stage mantle cell lymphoma","volume":"27","author":"Herrmann","year":"2009","journal-title":"J Clin Oncol"},{"key":"key20200714091949_b21-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1093\/annonc\/mdn045","article-title":"Intensive treatment strategies may not provide superior outcomes in mantle cell lymphoma: Overall survival exceeding 7 years with standard therapies","volume":"19","author":"Martin","year":"2008","journal-title":"Ann Oncol"},{"key":"key20200714091949_b22-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"604","DOI":"10.1002\/ajh.23176","article-title":"Mantle cell lymphoma: 2012 update on diagnosis, risk-stratification, and clinical management","volume":"87","author":"Vose","year":"2012","journal-title":"Am J Hematol"},{"key":"key20200714091949_b23-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/S1535-6108(03)00028-X","article-title":"The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma","volume":"3","author":"Rosenwald","year":"2003","journal-title":"Cancer Cell"},{"key":"key20200714091949_b24-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"4966","DOI":"10.1200\/JCO.2007.12.0410","article-title":"Five-gene model to predict survival in mantle-cell lymphoma using frozen or formalin-fixed, paraffin-embedded tissue","volume":"26","author":"Hartmann","year":"2008","journal-title":"J Clin Oncol"},{"key":"key20200714091949_b25-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"2385","DOI":"10.1182\/blood-2007-10-117010","article-title":"Ki-67 predicts outcome in advanced-stage mantle cell lymphoma patients treated with anti-CD20 immunochemotherapy: Results from randomized trials of the European MCL network and the German low Grade lymphoma Study Group","volume":"111","author":"Determann","year":"2008","journal-title":"Blood"},{"key":"key20200714091949_b26-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1182\/blood-2007-06-095331","article-title":"A new prognostic index (MIPI) for patients with advanced-stage mantle cell lymphoma","volume":"111","author":"Hoster","year":"2008","journal-title":"Blood"},{"key":"key20200714091949_b27-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1038\/ng.2254","article-title":"Mutations in the RNA exosome component gene EXOSC3 cause pontocerebellar hypoplasia and spinal motor neuron degeneration","volume":"44","author":"Wan","year":"2012","journal-title":"Nat Genet"},{"key":"key20200714091949_b28-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"1668","DOI":"10.1200\/JCO.2016.70.7901","article-title":"New molecular assay for the proliferation signature in mantle cell lymphoma applicable to formalin-fixed paraffin-embedded biopsies","volume":"35","author":"Scott","year":"2017","journal-title":"J Clin Oncol"},{"key":"key20200714091949_b29-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1038\/nprot.2008.211","article-title":"Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources","volume":"4","author":"Huang da","year":"2009","journal-title":"Nat Protoc"},{"key":"key20200714091949_b30-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1038\/75556","article-title":"Gene ontology: Tool for the unification of biology. The Gene Ontology Consortium","volume":"25","author":"Ashburner","year":"2000","journal-title":"Nat Genet"},{"key":"key20200714091949_b31-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"D330","DOI":"10.1093\/nar\/gky1055","article-title":"The Gene Ontology Resource: 20 years and still GOing strong","volume":"47","author":"The Gene Ontology Consortium","year":"2019","journal-title":"Nucleic Acids Res"},{"key":"key20200714091949_b32-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"D419","DOI":"10.1093\/nar\/gky1038","article-title":"PANTHER version 14: More genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools","volume":"47","author":"Mi","year":"2019","journal-title":"Nucleic Acids Res"},{"key":"key20200714091949_b33-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"2285","DOI":"10.1182\/blood-2014-04-571083","article-title":"The exosome complex establishes a barricade to erythroid maturation","volume":"124","author":"Mciver","year":"2014","journal-title":"Blood"},{"key":"key20200714091949_b34-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"5399","DOI":"10.1093\/emboj\/18.19.5399","article-title":"Functions of the exosome in rRNA, snoRNA and snRNA synthesis","volume":"18","author":"Allmang","year":"1999","journal-title":"EMBO J"},{"key":"key20200714091949_b35-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1016\/S0092-8674(00)80432-8","article-title":"The Exosome: A conserved eukaryotic RNA processing complex containing multiple 3\u2032->5\u2032Exoribonucleases","volume":"91","author":"Mitchell","year":"1997","journal-title":"Cell"},{"key":"key20200714091949_b36-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"6795","DOI":"10.1093\/nar\/gki982","article-title":"MPP6 is an exosome-associated RNA-binding protein involved in 5.8S rRNA maturation","volume":"33","author":"Schilders","year":"2005","journal-title":"Nucleic Acids Res"},{"key":"key20200714091949_b37-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1534\/genetics.107.073205","article-title":"A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism","volume":"177","author":"Wilson","year":"2016","journal-title":"Genetics"},{"key":"key20200714091949_b38-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"19958","DOI":"10.1074\/jbc.M702281200","article-title":"Localization of AU-rich element-containing mRNA in cytoplasmic granules containing exosome subunits","volume":"282","author":"Lin","year":"2007","journal-title":"J Biol Chem"},{"key":"key20200714091949_b39-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"4287","DOI":"10.1038\/ncomms5287","article-title":"EXOSC8 mutations alter mRNA metabolism and cause hypomyelination with spinal muscular atrophy and cerebellar hypoplasia","volume":"5","author":"Boczonadi","year":"2014","journal-title":"Nat Commun"},{"key":"key20200714091949_b40-ol-0-0-10850","doi-asserted-by":"publisher","first-page":"1903","DOI":"10.1182\/blood-2017-04-779736","article-title":"TP53 mutations identify younger mantle cell lymphoma patients who do not benefit from intensive chemoimmunotherapy","volume":"130","author":"Eskelund","year":"2017","journal-title":"Blood"}],"container-title":["Oncology Letters"],"original-title":[],"deposited":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T09:57:30Z","timestamp":1594720650000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/ol.2019.10850"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,11]]},"references-count":40,"URL":"https:\/\/doi.org\/10.3892\/ol.2019.10850","relation":{},"ISSN":["1792-1074","1792-1082"],"issn-type":[{"value":"1792-1074","type":"print"},{"value":"1792-1082","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,11]]}}}