{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T16:44:32Z","timestamp":1790441072013,"version":"4.1.0"},"reference-count":42,"publisher":"Spandidos Publications","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncol Lett"],"DOI":"10.3892\/ol.2025.15057","type":"journal-article","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T11:38:47Z","timestamp":1745494727000},"page":"1-9","source":"Crossref","is-referenced-by-count":1,"title":["Misdiagnosis of chordoma: A case report and a review of the literature"],"prefix":"10.3892","volume":"29","author":[{"given":"Dong","family":"Li","sequence":"first","affiliation":[{"name":"Department of Pathology, Qingdao Municipal Hospital, Qingdao, Shandong 266000, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengmeng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pathology, Qingdao Municipal Hospital, Qingdao, Shandong 266000, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Gynecology, Qingdao Municipal Hospital, Qingdao, Shandong 266000, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Qingdao Municipal Hospital, Qingdao, Shandong 266000, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Pathology, Qingdao Municipal Hospital, Qingdao, Shandong 266000, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2025,4,24]]},"reference":[{"key":"key20250513102153_b1-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"153089","DOI":"10.1016\/j.prp.2020.153089","article-title":"Chordomas: A review with emphasis on their pathophysiology, pathology, molecular biology, and genetics","volume":"216","author":"Karpathiou","year":"2020","journal-title":"Pathol Res Pract"},{"key":"key20250513102153_b2-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"899","DOI":"10.1097\/00000478-200007000-00001","article-title":"Chordoid meningioma: A clinicopathologic study of 42 cases","volume":"24","author":"Couce","year":"2000","journal-title":"Am J Surg Pathol"},{"key":"key20250513102153_b3-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"478","DOI":"10.3171\/2012.9.PEDS11398","article-title":"Intraventricular chordoid meningioma in a child: Fever of unknown origin, clinical course, and response to treatment","volume":"10","author":"Nambiar","year":"2012","journal-title":"J Neurosurg Pediatr"},{"key":"key20250513102153_b4-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"1461","DOI":"10.1038\/modpathol.2008.144","article-title":"Brachyury, SOX-9, and podoplanin, new markers in the skull base chordoma vs chondrosarcoma differential: A tissue microarray-based comparative analysis","volume":"21","author":"Oakley","year":"2008","journal-title":"Mod Pathol"},{"key":"key20250513102153_b5-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1093\/ptj\/23.3.140c","article-title":"M.R.C. War Memorandum: Aids to the investigation of peripheral nerve injuries","volume":"23","author":"Medical Research Council: Nerve Injuries Committee","year":"1943","journal-title":"Physical Therapy"},{"key":"key20250513102153_b6-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"1231","DOI":"10.1093\/neuonc\/noab106","article-title":"The 2021 WHO classification of tumors of the central nervous system: A summary","volume":"23","author":"Louis","year":"2021","journal-title":"Neuro Oncol"},{"key":"key20250513102153_b7-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1097\/PAP.0000000000000284","article-title":"The 2020 WHO classification of tumors of soft tissue: Selected changes and new entities","volume":"28","author":"Choi","year":"2021","journal-title":"Adv Anat Pathol"},{"key":"key20250513102153_b8-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1007\/s11060-010-0211-z","article-title":"Chordoid meningioma: A clinicopathologic study of 11 cases at a single institution","volume":"100","author":"Lin","year":"2010","journal-title":"J Neurooncol"},{"key":"key20250513102153_b9-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1007\/s40134-018-0275-7","article-title":"State-of-the-art imaging in human chordoma of the skull base","volume":"6","author":"Santegoeds","year":"2018","journal-title":"Curr Radiol Rep"},{"key":"key20250513102153_b10-ol-29-6-15057","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/B978-0-12-804257-1.00007-4","article-title":"Chapter 7 - Imaging Cranial Base Chordoma and Chondrosarcoma","volume-title":"Chordomas and Chondrosarcomas of the Skull Base and Spine","author":"Golden","year":"2018","edition":"2nd Edition"},{"key":"key20250513102153_b11-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"1525","DOI":"10.1148\/rg.295085215","article-title":"Sacral chordoma","volume":"29","author":"Farsad","year":"2009","journal-title":"Radiographics"},{"key":"key20250513102153_b12-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1016\/j.nec.2023.02.015","article-title":"Advanced meningioma imaging","volume":"34","author":"Loken","year":"2023","journal-title":"Neurosurg Clin N Am"},{"key":"key20250513102153_b13-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1097\/PAS.0b013e318194c566","article-title":"Distinguishing chordoid meningiomas from their histologic mimics: An immunohistochemical evaluation","volume":"33","author":"Sangoi","year":"2009","journal-title":"Am J Surg Pathol"},{"key":"key20250513102153_b14-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1046\/j.1432-0436.1995.5910043.x","article-title":"Changes in the expression of intermediate filaments and desmoplakins during development of human notochord","volume":"59","author":"Lehtonen","year":"1995","journal-title":"Differentiation"},{"key":"key20250513102153_b15-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1097\/00000478-199909000-00008","article-title":"Parachordoma is immunohistochemically and cytogenetically distinct from axial chordoma and extraskeletal myxoid chondrosarcoma","volume":"23","author":"Folpe","year":"1999","journal-title":"Am J Surg Pathol"},{"key":"key20250513102153_b16-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1002\/path.1969","article-title":"Brachyury, a crucial regulator of notochordal development, is a novel biomarker for chordomas","volume":"209","author":"Vujovic","year":"2006","journal-title":"J Pathol"},{"key":"key20250513102153_b17-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"151760","DOI":"10.1016\/j.anndiagpath.2021.151760","article-title":"Patterns of brachyury expression in chordomas","volume":"53","author":"Dridi","year":"2021","journal-title":"Ann Diagn Pathol"},{"key":"key20250513102153_b18-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.1097\/PAS.0000000000000462","article-title":"Nuclear brachyury expression is consistent in chordoma, common in germ cell tumors and small cell carcinomas, and rare in other carcinomas and sarcomas: An immunohistochemical study of 5229 cases","volume":"39","author":"Miettinen","year":"2015","journal-title":"Am J Surg Pathol"},{"key":"key20250513102153_b19-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1002\/gcc.1184","article-title":"Genome-wide analysis of sixteen chordomas by comparative genomic hybridization and cytogenetics of the first human chordoma cell line, U-CH1","volume":"32","author":"Scheil","year":"2001","journal-title":"Genes Chromosomes Cancer"},{"key":"key20250513102153_b20-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1038\/sj.bjc.6604130","article-title":"Frequent deletion of the CDKN2A locus in chordoma: Analysis of chromosomal imbalances using array comparative genomic hybridisation","volume":"98","author":"Hallor","year":"2008","journal-title":"Br J Cancer"},{"key":"key20250513102153_b21-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/j.cancergencyto.2003.09.015","article-title":"Combined binary ratio labeling fluorescence in situ hybridization analysis of chordoma","volume":"151","author":"Ku\u017aniacka","year":"2004","journal-title":"Cancer Genet Cytogenet"},{"key":"key20250513102153_b22-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"412","DOI":"10.4161\/cbt.8.5.8019","article-title":"The role of SMARCB1\/INI1 in development of rhabdoid tumor","volume":"8","author":"Roberts","year":"2009","journal-title":"Cancer Biol Ther"},{"key":"key20250513102153_b23-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1038\/nm.4036","article-title":"Targeting EZH2 in cancer","volume":"22","author":"Kim","year":"2016","journal-title":"Nat Med"},{"key":"key20250513102153_b24-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"1170","DOI":"10.5858\/2009-0380-OA.1","article-title":"The prognostic value of Ki-67, p53, epidermal growth factor receptor, 1p36, 9p21, 10q23, and 17p13 in skull base chordomas","volume":"134","author":"Horbinski","year":"2010","journal-title":"Arch Pathol Lab Med"},{"key":"key20250513102153_b25-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"1048482","DOI":"10.3389\/fonc.2022.1048482","article-title":"Low expression of H3K27me3 is associated with poor prognosis in conventional chordoma","volume":"12","author":"Wei","year":"2022","journal-title":"Front Oncol"},{"key":"key20250513102153_b26-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1038\/nature09784","article-title":"The polycomb complex PRC2 and its mark in life","volume":"469","author":"Margueron","year":"2011","journal-title":"Nature"},{"key":"key20250513102153_b27-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"188796","DOI":"10.1016\/j.bbcan.2022.188796","article-title":"Chordoma: To know means to recognize","volume":"1877","author":"Karele","year":"2022","journal-title":"Biochim Biophys Acta Rev Cancer"},{"key":"key20250513102153_b28-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"6833","DOI":"10.1158\/1078-0432.CCR-17-1087","article-title":"Phase I study of a poxviral TRICOM-based vaccine directed against the transcription factor brachyury","volume":"23","author":"Heery","year":"2017","journal-title":"Clin Cancer Res"},{"key":"key20250513102153_b29-ol-29-6-15057","article-title":"Spinal Chordomas: Current Medical and Surgical Management: JSM Neurosurgery and Spine","author":"Yurter","year":"2014"},{"key":"key20250513102153_b30-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1186\/s13018-018-0784-3","article-title":"Analysis of prognostic factors for survival in patients with primary spinal chordoma using the SEER Registry from 1973 to 2014","volume":"13","author":"Pan","year":"2018","journal-title":"J Orthop Surg Res"},{"key":"key20250513102153_b31-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1186\/s40478-022-01362-3","article-title":"Epigenetic and genomic profiling of chordoid meningioma: Implications for clinical management","volume":"10","author":"Daoud","year":"2022","journal-title":"Acta Neuropathol Commun"},{"key":"key20250513102153_b32-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1080\/02688697.2020.1861436","article-title":"Chordoid meningioma: Report of 5 cases and review of the literature","volume":"37","author":"Tahta","year":"2023","journal-title":"Br J Neurosurg"},{"key":"key20250513102153_b33-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1227\/neu.0000000000002272","article-title":"Favorable long-term outcomes of chordoid meningioma compared with the other WHO grade 2 meningioma subtypes","volume":"92","author":"Ren","year":"2023","journal-title":"Neurosurgery"},{"key":"key20250513102153_b34-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1111\/cyt.12631","article-title":"Clinicocytopathological spectrum, including uncommon forms, of nine cases of chordomas with immunohistochemical results, including brachyury immunostaining: A single institutional experience","volume":"30","author":"Rekhi","year":"2019","journal-title":"Cytopathology"},{"key":"key20250513102153_b35-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1080\/00313020410001672074","article-title":"Chordoid meningioma masquerading as chordoma","volume":"36","author":"Murali","year":"2004","journal-title":"Pathology"},{"key":"key20250513102153_b36-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1002\/path.2816","article-title":"Role of the transcription factor T (brachyury) in the pathogenesis of sporadic chordoma: A genetic and functional-based study","volume":"223","author":"Presneau","year":"2011","journal-title":"J Pathol"},{"key":"key20250513102153_b37-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1038\/s41467-018-02826-8","article-title":"A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle","volume":"9","author":"Goode","year":"2018","journal-title":"Nat Commuml"},{"key":"key20250513102153_b38-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1111\/j.1750-3639.1999.tb00543.x","article-title":"Chordoid glioma of the third ventricle: Immunohistochemical and molecular genetic characterization of a novel tumor entity","volume":"9","author":"Reifenberger","year":"1999","journal-title":"Brain Pathol"},{"key":"key20250513102153_b39-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"1379","DOI":"10.1007\/s00402-012-1557-9","article-title":"Extraskeletal myxoid chondrosarcoma: A review of 23 patients treated at a single referral center with long-term follow-up","volume":"132","author":"Ogura","year":"2012","journal-title":"Arch Orthop Trauma Surg"},{"key":"key20250513102153_b40-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1007\/s00428-012-1240-0","article-title":"NR4A3 rearrangement reliably distinguishes between the clinicopathologically overlapping entities myoepithelial carcinoma of soft tissue and cellular extraskeletal myxoid chondrosarcoma","volume":"460","author":"Flucke","year":"2012","journal-title":"Virchows Archiv"},{"key":"key20250513102153_b41-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1002\/path.2913","article-title":"IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours","volume":"224","author":"Amary","year":"2011","journal-title":"J Pathol"},{"key":"key20250513102153_b42-ol-29-6-15057","doi-asserted-by":"publisher","first-page":"1256","DOI":"10.1038\/ng.1004","article-title":"Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome","volume":"43","author":"Pansuriya","year":"2011","journal-title":"Nat Genet"}],"container-title":["Oncology Letters"],"original-title":[],"deposited":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T07:22:00Z","timestamp":1747120920000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/ol.2025.15057"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,24]]},"references-count":42,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2025,4,24]]}},"URL":"https:\/\/doi.org\/10.3892\/ol.2025.15057","relation":{},"ISSN":["1792-1074","1792-1082"],"issn-type":[{"value":"1792-1074","type":"print"},{"value":"1792-1082","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,24]]}}}