{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T06:43:15Z","timestamp":1792478595956,"version":"4.5.0"},"reference-count":32,"publisher":"Spandidos Publications","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncol Lett"],"DOI":"10.3892\/ol.2026.15845","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T11:00:33Z","timestamp":1788433233000},"page":"1-8","source":"Crossref","is-referenced-by-count":0,"title":["Seven\u2011year follow\u2011up demonstrating sustained survival following\n                    <sup>125<\/sup>\n                    I seed brachytherapy in an elderly patient with lip squamous cell carcinoma and Alzheimer's disease: A case report"],"prefix":"10.3892","volume":"32","author":[{"given":"Guangsheng","family":"Zhao","sequence":"first","affiliation":[{"name":"Cancer Interventional Center, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning 116001, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Zhou","sequence":"additional","affiliation":[{"name":"Cancer Interventional Center, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning 116001, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunhang","family":"Yin","sequence":"additional","affiliation":[{"name":"Cancer Interventional Center, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning 116001, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Xu","sequence":"additional","affiliation":[{"name":"Cancer Interventional Center, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning 116001, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Licai","family":"Xu","sequence":"additional","affiliation":[{"name":"Cancer Interventional Center, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning 116001, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiushi","family":"Wang","sequence":"additional","affiliation":[{"name":"Cancer Interventional Center, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning 116001, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Zhou","sequence":"additional","affiliation":[{"name":"Cancer Interventional Center, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning 116001, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song","family":"Liu","sequence":"additional","affiliation":[{"name":"Dalian Medical University, Dalian, Liaoning 116044, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2026,9,3]]},"reference":[{"key":"key20261020093144_b1-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"104551","DOI":"10.1016\/j.oraloncology.2019.104551","article-title":"Global patterns and trends in cancers of the lip, tongue and mouth","volume":"102","author":"Miranda-Filho","year":"2020","journal-title":"Oral Oncol"},{"key":"key20261020093144_b2-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1038\/s41368-023-00249-w","article-title":"Oral squamous cell carcinomas: State of the field and emerging directions","volume":"15","author":"Tan","year":"2023","journal-title":"Int J Oral Sci"},{"key":"key20261020093144_b3-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"100850","DOI":"10.1016\/j.tranon.2020.100850","article-title":"Onodera's prognostic nutritional index correlates with tumor immune environment and survival in patients with oral squamous cell carcinoma undergoing chemoradiotherapy","volume":"13","author":"Yoshida","year":"2020","journal-title":"Transl Oncol"},{"key":"key20261020093144_b4-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1002\/hed.23626","article-title":"Concurrent chemoradiotherapy compared with surgery and adjuvant radiotherapy for oral cavity squamous cell carcinoma","volume":"37","author":"Gore","year":"2015","journal-title":"Head Neck"},{"key":"key20261020093144_b5-ol-32-5-15845","first-page":"29","article-title":"The effect of the surgical margins on the outcome of patients with head and neck squamous cell carcinoma: Single institution experience","volume":"9","author":"Eldeeb","year":"2012","journal-title":"Cancer Biol Med"},{"key":"key20261020093144_b6-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"9594","DOI":"10.3390\/ijms23179594","article-title":"The effect of Intensity-modulated radiotherapy to the head and neck region on the oral innate immune response and oral microbiome: A prospective cohort study of head and neck tumour patients","volume":"23","author":"Mojdami","year":"2022","journal-title":"Int J Mol Sci"},{"key":"key20261020093144_b7-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"1922","DOI":"10.1200\/JCO.23.01951","article-title":"Development and standardization of an osteoradionecrosis classification system in head and neck cancer: Implementation of a Risk-based model","volume":"42","author":"Watson","year":"2024","journal-title":"J Clin Oncol"},{"key":"key20261020093144_b8-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1186\/s12877-025-06313-w","article-title":"Efficacy and safety of CT-guided 125I particle implantation for the treatment of elderly lung cancer: A system evaluation and meta-analysis","volume":"25","author":"Li","year":"2025","journal-title":"BMC Geriatr"},{"key":"key20261020093144_b9-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1186\/s40644-025-00909-6","article-title":"Investigation into the efficiency and prognostic elements of CT-guided 125I particle implantation for liver cancer","volume":"25","author":"Xia","year":"2025","journal-title":"Cancer Imaging"},{"key":"key20261020093144_b10-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"101618","DOI":"10.1016\/j.suronc.2021.101618","article-title":"Iodine-125 radioactive seed brachytherapy as a treatment for spine and bone metastases: A systematic review and meta-analysis","volume":"38","author":"Sharma","year":"2021","journal-title":"Surg Oncol"},{"key":"key20261020093144_b11-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"1041","DOI":"10.1080\/09553002.2024.2347357","article-title":"The efficacy of coaxial percutaneous iodine-125 seed implantation combined with arterial infusion chemotherapy for advanced pancreatic cancer: A randomized clinical trial","volume":"100","author":"Yao","year":"2024","journal-title":"Int J Radiat Biol"},{"key":"key20261020093144_b12-ol-32-5-15845","first-page":"113","article-title":"Image-guided percutaneous (125)I seed implantation as a salvage treatment for recurrent soft tissue sarcomas after surgery and radiotherapy","volume":"26","author":"Li","year":"2011","journal-title":"Cancer Biother Radiopharm"},{"key":"key20261020093144_b13-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"642","DOI":"10.4103\/jcrt.jcrt_1891_23","article-title":"Efficacy of radioactive 125I seed implantation in treating inoperable or refused operation head and neck cancers","volume":"20","author":"Zhang","year":"2024","journal-title":"J Cancer Res Ther"},{"key":"key20261020093144_b14-ol-32-5-15845","first-page":"1680","article-title":"Interstitial brachytherapy of oral squamous cell carcinoma with ultrasound-guided iodine-125 radioactive seed implantation","volume":"22","author":"Tian","year":"2018","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"key20261020093144_b15-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1016\/S0261-5614(02)00214-5","article-title":"Nutritional risk screening (NRS 2002): A new method based on an analysis of controlled clinical trials","volume":"22","author":"Kondrup","year":"2003","journal-title":"Clin Nutr"},{"key":"key20261020093144_b16-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1016\/j.jpainsymman.2010.08.016","article-title":"Studies comparing numerical rating scales, verbal rating scales, and visual analogue scales for assessment of pain intensity in adults: A systematic literature review","volume":"41","author":"Hjermstad","year":"2011","journal-title":"J Pain Symptom Manage"},{"key":"key20261020093144_b17-ol-32-5-15845","article-title":"AJCC Cancer Staging Manual","author":"Amin","year":"2017","edition":"8th edition"},{"key":"key20261020093144_b18-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"3731","DOI":"10.1038\/s41598-022-07729-9","article-title":"Evaluation of the efficacy of CT-guided 3D template-assisted 125I seed implantation in the treatment of unresectable STS: A multicenter retrospective study","volume":"12","author":"Zhao","year":"2022","journal-title":"Sci Rep"},{"key":"key20261020093144_b19-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1186\/s12885-020-07223-3","article-title":"Evaluation of radioactive (125)I seed implantation for the treatment of refractory malignant tumours based on a CT-guided 3D template-assisted technique: Efficacy and safety","volume":"20","author":"Zhao","year":"2020","journal-title":"BMC Cancer"},{"key":"key20261020093144_b20-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1200\/JCO.1984.2.3.187","article-title":"Karnofsky performance status revisited: Reliability, validity, and guidelines","volume":"2","author":"Schag","year":"1984","journal-title":"J Clin Oncol"},{"key":"key20261020093144_b21-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"720","DOI":"10.4103\/jcrt.JCRT_563_20","article-title":"The clinical efficacy of computed tomography-guided (125)I particle implantation combined with arterial infusion chemotherapy in the treatment of pancreatic cancer","volume":"17","author":"Yang","year":"2021","journal-title":"J Cancer Res Ther"},{"key":"key20261020093144_b22-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"882061","DOI":"10.3389\/fonc.2022.882061","article-title":"CalliSpheres\u00ae microsphere transarterial chemoembolization combined with 125I brachytherapy for patients with non-small-cell lung cancer liver metastases","volume":"12","author":"Zhao","year":"2022","journal-title":"Front Oncol"},{"key":"key20261020093144_b23-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.4103\/jcrt.jcrt_2638_22","article-title":"Computed tomography-guided radioactive iodine-125 seed implantation for liver malignancies in challenging locations","volume":"20","author":"Li","year":"2024","journal-title":"J Cancer Res Ther"},{"key":"key20261020093144_b24-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"1589325","DOI":"10.3389\/fonc.2025.1589325","article-title":"Dose and local efficacy analysis of iodine-125 seed implantation therapy for lung tumors","volume":"15","author":"Cao","year":"2025","journal-title":"Front Oncol"},{"key":"key20261020093144_b25-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"e0347893","DOI":"10.1371\/journal.pone.0347893","article-title":"The radioactive 3D-printed template-assisted CT-guided 125I seed implantation for refractory bone metastases: A multicenter retrospective analysis of efficacy, safety, and immune function changes","volume":"21","author":"Zhao","year":"2026","journal-title":"PLoS One"},{"key":"key20261020093144_b26-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"664996","DOI":"10.3389\/fonc.2021.664996","article-title":"The accuracy of individualized 3D-printing template-assisted I(125) radioactive seed implantation for recurrent\/metastatic head and neck cancer","volume":"11","author":"Qiu","year":"2021","journal-title":"Front Oncol"},{"key":"key20261020093144_b27-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"28","DOI":"10.5114\/jcb.2019.83336","article-title":"Five-year outcome of ultrasound-guided interstitial permanent (125)I seeds implantation for local head and neck recurrent tumors: A single center retrospective study","volume":"11","author":"Jiang","year":"2019","journal-title":"J Contemp Brachytherapy"},{"key":"key20261020093144_b28-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"e0330271","DOI":"10.1371\/journal.pone.0330271","article-title":"Dosimetry study of 3D-printed noncoplanar template-assisted CT-guided 125I seed implantation for the treatment of recurrent and metastatic tumors in the head and neck","volume":"20","author":"Qiu","year":"2025","journal-title":"PLoS One"},{"key":"key20261020093144_b29-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.brachy.2016.06.013","article-title":"The American College of Radiology and the American Brachytherapy Society practice parameter for the performance of low-dose-rate brachytherapy","volume":"16","author":"Viswanathan","year":"2017","journal-title":"Brachytherapy"},{"key":"key20261020093144_b30-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"1190","DOI":"10.1016\/S0360-3016(01)01567-X","article-title":"The American Brachytherapy Society recommendations for high-dose-rate brachytherapy for head-and-neck carcinoma","volume":"50","author":"Nag","year":"2001","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"key20261020093144_b31-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1186\/s13014-021-01845-y","article-title":"Dosimetry study of three-dimensional print template for 125I implantation therapy","volume":"16","author":"Chen","year":"2021","journal-title":"Radiat Oncol"},{"key":"key20261020093144_b32-ol-32-5-15845","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1186\/s13014-018-0959-4","article-title":"Side effects of CT-guided implantation of (125)I seeds for recurrent malignant tumors of the head and neck assisted by 3D printing non co-planar template","volume":"13","author":"Jiang","year":"2018","journal-title":"Radiat Oncol"}],"container-title":["Oncology Letters"],"original-title":[],"deposited":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T06:31:50Z","timestamp":1792477910000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.spandidos-publications.com\/10.3892\/ol.2026.15845"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,3]]},"references-count":32,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2026,9,3]]}},"URL":"https:\/\/doi.org\/10.3892\/ol.2026.15845","relation":{},"ISSN":["1792-1074","1792-1082"],"issn-type":[{"value":"1792-1074","type":"print"},{"value":"1792-1082","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,3]]}}}