{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T18:03:25Z","timestamp":1790705005564,"version":"4.1.0"},"reference-count":46,"publisher":"Spandidos Publications","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,11]]},"DOI":"10.3892\/or.2012.1975","type":"journal-article","created":{"date-parts":[[2012,8,22]],"date-time":"2012-08-22T06:15:40Z","timestamp":1345616140000},"page":"1859-1868","source":"Crossref","is-referenced-by-count":29,"title":["Polymorphisms in base excision repair genes and thyroid cancer risk"],"prefix":"10.3892","volume":"28","author":[{"given":"LU\u00cdS S.","family":"SANTOS","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SANDRA C.","family":"BRANCO","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SUSANA N.","family":"SILVA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ANA PAULA","family":"AZEVEDO","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"OCT\u00c1VIA M.","family":"GIL","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ISABEL","family":"MANITA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"TERESA C.","family":"FERREIRA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"EDWARD","family":"LIMBERT","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JOS\u00c9","family":"RUEFF","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JORGE F.","family":"GASPAR","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2012,8,22]]},"reference":[{"key":"key20180107215643_b1-or-28-05-1859","first-page":"51","article-title":"Tumours of the thyroid and parathyroid","volume-title":"Pathology and Genetics of Tumours of Endocrine Organs","author":"De Lellis","year":"2004"},{"key":"key20180107215643_b2-or-28-05-1859","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s10552-008-9219-5","article-title":"Risk factors for thyroid cancer: an epidemiological review focused on nutritional factors","volume":"20","author":"Dal Maso","year":"2009","journal-title":"Cancer Causes Control"},{"key":"key20180107215643_b3-or-28-05-1859","doi-asserted-by":"crossref","first-page":"R43","DOI":"10.1530\/JME-11-0005","article-title":"Association studies in thyroid cancer susceptibility: are we on the right track?","volume":"47","author":"Landa","year":"2011","journal-title":"J Mol Endocrinol"},{"key":"key20180107215643_b4-or-28-05-1859","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0764-4469(99)80037-7","article-title":"Mechanisms of mutagenesis in mammalian cells. Application to human thyroid tumours","volume":"322","author":"Sarasin","year":"1999","journal-title":"C R Acad Sci III"},{"key":"key20180107215643_b5-or-28-05-1859","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S1470-2045(09)70020-8","article-title":"Germ-line DNA polymorphisms and susceptibility to differentiated thyroid cancer","volume":"10","author":"Adjadj","year":"2009","journal-title":"Lancet Oncol"},{"key":"key20180107215643_b6-or-28-05-1859","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1038\/ng.339","article-title":"Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations","volume":"41","author":"Gudmundsson","year":"2009","journal-title":"Nat Genet"},{"key":"key20180107215643_b7-or-28-05-1859","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1038\/35077232","article-title":"Genome maintenance mechanisms for preventing cancer","volume":"411","author":"Hoeijmakers","year":"2001","journal-title":"Nature"},{"key":"key20180107215643_b8-or-28-05-1859","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.mrgentox.2005.07.001","article-title":"DNA damage among thyroid cancer and multiple cancer cases, controls, and long-lived individuals","volume":"586","author":"Sigurdson","year":"2005","journal-title":"Mutat Res"},{"key":"key20180107215643_b9-or-28-05-1859","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.canlet.2009.08.007","article-title":"An epitome of DNA repair related genes and mechanisms in thyroid carcinoma","volume":"290","author":"Gatzidou","year":"2010","journal-title":"Cancer Lett"},{"key":"key20180107215643_b10-or-28-05-1859","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.mrfmmm.2010.12.004","article-title":"Variation in base excision repair capacity","volume":"711","author":"Wilson","year":"2011","journal-title":"Mutat Res"},{"key":"key20180107215643_b11-or-28-05-1859","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1093\/aje\/kwi318","article-title":"Genetic polymorphisms in the base excision repair pathway and cancer risk: a HuGE review","volume":"162","author":"Hung","year":"2005","journal-title":"Am J Epidemiol"},{"key":"key20180107215643_b12-or-28-05-1859","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1158\/1055-9965.EPI-05-0230","article-title":"Association of polymorphisms in ERCC2 gene with non-familial thyroid cancer risk","volume":"14","author":"Silva","year":"2005","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"key20180107215643_b13-or-28-05-1859","first-page":"1079","article-title":"The role of common variants of non-homologous end-joining repair genes XRCC4, LIG4 and Ku80 in thyroid cancer risk","volume":"24","author":"Gomes","year":"2010","journal-title":"Oncol Rep"},{"key":"key20180107215643_b14-or-28-05-1859","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1089\/thy.2009.0099","article-title":"Association of polymorphisms in genes of the homologous recombination DNA repair pathway and thyroid cancer risk","volume":"19","author":"Bastos","year":"2009","journal-title":"Thyroid"},{"key":"key20180107215643_b15-or-28-05-1859","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1089\/thy.2011.0117","article-title":"Association of BRCA1 functional single nucleotide polymorphisms with risk of differentiated thyroid carcinomaa","volume":"22","author":"Xu","year":"2012","journal-title":"Thyroid"},{"key":"key20180107215643_b16-or-28-05-1859","first-page":"459","article-title":"DNA repair perspectives in thyroid and breast cancer: the role of DNA repair polymorphisms","volume-title":"DNA Repair and Human Health","author":"Silva","year":"2011"},{"key":"key20180107215643_b17-or-28-05-1859","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1093\/carcin\/22.6.917","article-title":"Amino acid substitution variants of APE1 and XRCC1 genes associated with ionizing radiation sensitivity","volume":"22","author":"Hu","year":"2001","journal-title":"Carcinogenesis"},{"key":"key20180107215643_b18-or-28-05-1859","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1093\/carcin\/bgl187","article-title":"Association of DNA repair polymorphisms with DNA repair functional outcomes in healthy human subjects","volume":"28","author":"Vodicka","year":"2007","journal-title":"Carcinogenesis"},{"key":"key20180107215643_b19-or-28-05-1859","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.cdp.2007.07.001","article-title":"Menopausal age and XRCC1 gene polymorphisms: role in breast cancer risk","volume":"31","author":"Silva","year":"2007","journal-title":"Cancer Detect Prev"},{"key":"key20180107215643_b20-or-28-05-1859","first-page":"A1886","article-title":"Mendel version 4.0: a complete package for the exact genetic analysis of discrete traits in pedigree and population data sets","volume":"69","author":"Lange","year":"2001","journal-title":"Am J Hum Genet"},{"key":"key20180107215643_b21-or-28-05-1859","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/s11060-008-9556-y","article-title":"XRCC1 and XRCC3 variants and risk of glioma and meningioma","volume":"88","author":"Kiuru","year":"2008","journal-title":"J Neurooncol"},{"key":"key20180107215643_b22-or-28-05-1859","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1158\/1055-9965.EPI-05-0653","article-title":"Genetic polymorphisms in base-excision repair pathway genes and risk of breast cancer","volume":"15","author":"Zhang","year":"2006","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"key20180107215643_b23-or-28-05-1859","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1186\/1471-2407-9-344","article-title":"Association of common variants in mismatch repair genes and breast cancer susceptibility: a multigene study","volume":"9","author":"Conde","year":"2009","journal-title":"BMC Cancer"},{"key":"key20180107215643_b24-or-28-05-1859","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.mrrev.2011.02.001","article-title":"Polymorphism in the DNA repair enzyme XRCC1: utility of current database and implications for human health risk assessment","volume":"727","author":"Ginsberg","year":"2011","journal-title":"Mutat Res"},{"key":"key20180107215643_b25-or-28-05-1859","doi-asserted-by":"crossref","first-page":"5919","DOI":"10.1158\/1078-0432.CCR-08-0906","article-title":"Association between polymorphisms in DNA base excision repair genes XRCC1, APE1, and ADPRT and differentiated thyroid carcinoma","volume":"14","author":"Chiang","year":"2008","journal-title":"Clin Cancer Res"},{"key":"key20180107215643_b26-or-28-05-1859","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.mrfmmm.2011.03.003","article-title":"Association studies of OGG1, XRCC1, XRCC2 and XRCC3 polymorphisms with differentiated thyroid cancer","volume":"709\u2013710","author":"Garc\u00eda-Quispes","year":"2011","journal-title":"Mutat Res"},{"key":"key20180107215643_b27-or-28-05-1859","doi-asserted-by":"crossref","first-page":"991","DOI":"10.3346\/jkms.2011.26.8.991","article-title":"XRCC1 polymorphisms and risk of papillary thyroid carcinoma in a Korean sample","volume":"26","author":"Ryu","year":"2011","journal-title":"J Korean Med Sci"},{"key":"key20180107215643_b28-or-28-05-1859","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1667\/RR1327.1","article-title":"Thyroid nodules, polymorphic variants in DNA repair and RET-related genes, and interaction with ionizing radiation exposure from nuclear tests in Kazakhstan","volume":"171","author":"Sigurdson","year":"2009","journal-title":"Radiat Res"},{"key":"key20180107215643_b29-or-28-05-1859","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1089\/thy.2008.0153","article-title":"Association of XRCC1 polymorphisms and risk of differentiated thyroid carcinoma: a case-control analysis","volume":"19","author":"Ho","year":"2009","journal-title":"Thyroid"},{"key":"key20180107215643_b30-or-28-05-1859","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1677\/ERC-08-0336","article-title":"Polymorphisms of DNA damage response genes in radiation-related and sporadic papillary thyroid carcinoma","volume":"16","author":"Akulevich","year":"2009","journal-title":"Endocr Relat Cancer"},{"key":"key20180107215643_b31-or-28-05-1859","doi-asserted-by":"crossref","first-page":"e27545","DOI":"10.1371\/journal.pone.0027545","article-title":"The effect of hOGG1 Ser326Cys polymorphism on cancer risk: evidence from a meta-analysis","volume":"6","author":"Wei","year":"2011","journal-title":"PLoS One"},{"key":"key20180107215643_b32-or-28-05-1859","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1007\/s10549-009-0723-4","article-title":"Lack of association between the hOGG1 Ser326Cys polymorphism and breast cancer risk: evidence from 11 case-control studies","volume":"122","author":"Gu","year":"2010","journal-title":"Breast Cancer Res Treat"},{"key":"key20180107215643_b33-or-28-05-1859","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1007\/s10549-009-0722-5","article-title":"The hOGG1 Ser326Cys polymorphism and breast cancer risk: a meta-analysis","volume":"122","author":"Yuan","year":"2010","journal-title":"Breast Cancer Res Treat"},{"key":"key20180107215643_b34-or-28-05-1859","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1038\/nature05978","article-title":"Base-excision repair of oxidative DNA damage","volume":"447","author":"David","year":"2007","journal-title":"Nature"},{"key":"key20180107215643_b35-or-28-05-1859","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.dnarep.2006.11.001","article-title":"MUTYH-associated polyposis - from defect in base excision repair to clinical genetic testing","volume":"6","author":"Cheadle","year":"2007","journal-title":"DNA Repair"},{"key":"key20180107215643_b36-or-28-05-1859","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1002\/ijc.21905","article-title":"MUTYH-associated polyposis: 70 of 71 patients with biallelic mutations present with an attenuated or atypical phenotype","volume":"119","author":"Aretz","year":"2006","journal-title":"Int J Cancer"},{"key":"key20180107215643_b37-or-28-05-1859","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/s10689-010-9366-1","article-title":"Papillary thyroid cancer in a patient with MUTYH-associated polyposis (MAP)","volume":"9","author":"Pervaiz","year":"2010","journal-title":"Fam Cancer"},{"key":"key20180107215643_b38-or-28-05-1859","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1053\/j.gastro.2008.04.035","article-title":"Characterization of mutant MUTYH proteins associated with familial colorectal cancer","volume":"135","author":"Ali","year":"2008","journal-title":"Gastroenterology"},{"key":"key20180107215643_b39-or-28-05-1859","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1016\/j.ejca.2010.01.013","article-title":"Common variants in human CRC genes as low-risk alleles","volume":"46","author":"Picelli","year":"2010","journal-title":"Eur J Cancer"},{"key":"key20180107215643_b40-or-28-05-1859","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1111\/j.1349-7006.2007.00694.x","article-title":"Association between genetic polymorphisms of the base excision repair gene MUTYH and increased colorectal cancer risk in a Japanese population","volume":"99","author":"Tao","year":"2008","journal-title":"Cancer Sci"},{"key":"key20180107215643_b41-or-28-05-1859","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1756-9966-28-10","article-title":"MUTYH Gln324His gene polymorphism and genetic susceptibility for lung cancer in a Japanese population","volume":"28","author":"Miyaishi","year":"2009","journal-title":"J Exp Clin Cancer Res"},{"key":"key20180107215643_b42-or-28-05-1859","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.lungcan.2010.11.018","article-title":"Association of genetic polymorphisms in DNA repair pathway genes with non-small cell lung cancer risk","volume":"73","author":"Qian","year":"2011","journal-title":"Lung Cancer"},{"key":"key20180107215643_b43-or-28-05-1859","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1158\/1055-9965.EPI-06-0712","article-title":"High-order interactions among genetic variants in DNA base excision repair pathway genes and smoking in bladder cancer susceptibility","volume":"16","author":"Huang","year":"2007","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"key20180107215643_b44-or-28-05-1859","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/978-1-59745-416-2_16","article-title":"Polymorphisms of DNA repair genes: ADPRT, XRCC1, and XPD and cancer risk in genetic epidemiology","volume":"471","author":"Jiang","year":"2009","journal-title":"Methods Mol Biol"},{"key":"key20180107215643_b45-or-28-05-1859","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1053\/j.gastro.2006.05.050","article-title":"Adenosine diphosphate ribosyl transferase and X-ray repair cross-complementing 1 polymorphisms in gastric cardia cancer","volume":"131","author":"Miao","year":"2006","journal-title":"Gastroenterology"},{"key":"key20180107215643_b46-or-28-05-1859","first-page":"247","article-title":"Polymorphisms of ADPRT Val762Ala and XRCC1 Arg399Glu and risk of breast cancer in Chinese women: a case control analysis","volume":"15","author":"Zhai","year":"2006","journal-title":"Oncol Rep"}],"container-title":["Oncology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/or.2012.1975\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,1,7]],"date-time":"2018-01-07T21:56:57Z","timestamp":1515362217000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/or.2012.1975"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8,22]]},"references-count":46,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2012,8,22]]},"published-print":{"date-parts":[[2012,11]]}},"alternative-id":["10.3892\/or.2012.1975"],"URL":"https:\/\/doi.org\/10.3892\/or.2012.1975","relation":{},"ISSN":["1021-335X","1791-2431"],"issn-type":[{"value":"1021-335X","type":"print"},{"value":"1791-2431","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,8,22]]}}}