{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T20:45:21Z","timestamp":1791146721268,"version":"4.1.0"},"reference-count":25,"publisher":"Spandidos Publications","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,7]]},"DOI":"10.3892\/or.2014.3203","type":"journal-article","created":{"date-parts":[[2014,5,20]],"date-time":"2014-05-20T12:29:34Z","timestamp":1400588974000},"page":"189-198","source":"Crossref","is-referenced-by-count":32,"title":["Overexpression of goosecoid homeobox is associated with chemoresistance and poor prognosis in ovarian carcinoma"],"prefix":"10.3892","volume":"32","author":[{"given":"KYONG-WON","family":"KANG","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MI-JUNG","family":"LEE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JI-AE","family":"SONG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JU-YEON","family":"JEONG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YOO-KYONG","family":"KIM","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CHAN","family":"LEE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"TAE-HEON","family":"KIM","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KYU-BEOM","family":"KWAK","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"OK-JUN","family":"KIM","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HEE JUNG","family":"AN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2014,5,20]]},"reference":[{"key":"key20180107210240_b1-or-32-01-0189","doi-asserted-by":"crossref","first-page":"23","DOI":"10.3322\/canjclin.52.1.23","article-title":"Cancer statistics, 2002","volume":"52","author":"Jemal","year":"2002","journal-title":"CA Cancer J Clin"},{"key":"key20180107210240_b2-or-32-01-0189","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1056\/NEJM199601043340101","article-title":"Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer","volume":"334","author":"McGuire","year":"1996","journal-title":"New Engl J Med"},{"key":"key20180107210240_b3-or-32-01-0189","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/S0002-9440(10)64744-X","article-title":"Bcl-2 and p53 protein expression, apoptosis, and p53 mutation in human epithelial ovarian cancers","volume":"156","author":"Chan","year":"2000","journal-title":"Am J Pathol"},{"key":"key20180107210240_b4-or-32-01-0189","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1016\/S0002-9440(10)63708-X","article-title":"Ovarian tumorigenesis: a proposed model based on morphological and molecular genetic analysis","volume":"164","author":"Shih Ie","year":"2004","journal-title":"Am J Pathol"},{"key":"key20180107210240_b5-or-32-01-0189","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1038\/nrc1123","article-title":"Ovarian cancer: strategies for overcoming resistance to chemotherapy","volume":"3","author":"Agarwal","year":"2003","journal-title":"Nat Rev Cancer"},{"key":"key20180107210240_b6-or-32-01-0189","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.drup.2009.09.001","article-title":"Novel strategies for reversing platinum resistance","volume":"12","author":"Shahzad","year":"2009","journal-title":"Drug Resist Updat"},{"key":"key20180107210240_b7-or-32-01-0189","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/j.ctrv.2007.07.013","article-title":"A systematic review of platinum and taxane resistance from bench to clinic: an inverse relationship","volume":"33","author":"Stordal","year":"2007","journal-title":"Cancer Treat Rev"},{"key":"key20180107210240_b8-or-32-01-0189","doi-asserted-by":"crossref","first-page":"5511","DOI":"10.1038\/onc.2008.246","article-title":"Drug discovery approaches targeting the PI3K\/Akt pathway in cancer","volume":"27","author":"Garcia-Echeverria","year":"2008","journal-title":"Oncogene"},{"key":"key20180107210240_b9-or-32-01-0189","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1002\/cam4.4","article-title":"Overexpression of snail induces epithelial-mesenchymal transition and a cancer stem cell-like phenotype in human colorectal cancer cells","volume":"1","author":"Fan","year":"2012","journal-title":"Cancer Med"},{"key":"key20180107210240_b10-or-32-01-0189","doi-asserted-by":"crossref","first-page":"2400","DOI":"10.1158\/0008-5472.CAN-08-4312","article-title":"Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway","volume":"69","author":"Wang","year":"2009","journal-title":"Cancer Res"},{"key":"key20180107210240_b11-or-32-01-0189","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1186\/1471-2407-12-91","article-title":"EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer","volume":"12","author":"Haslehurst","year":"2012","journal-title":"BMC Cancer"},{"key":"key20180107210240_b12-or-32-01-0189","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.ygyno.2004.12.043","article-title":"Snail and Slug are major determinants of ovarian cancer invasiveness at the transcription level","volume":"97","author":"Kurrey","year":"2005","journal-title":"Gynecol Oncol"},{"key":"key20180107210240_b13-or-32-01-0189","doi-asserted-by":"crossref","first-page":"2519","DOI":"10.1056\/NEJMra041842","article-title":"Cancer of the ovary","volume":"351","author":"Cannistra","year":"2004","journal-title":"N Engl J Med"},{"key":"key20180107210240_b14-or-32-01-0189","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.canlet.2008.06.012","article-title":"Effect of tumor suppressor gene PTEN on the resistance to cisplatin in human ovarian cancer cell lines and related mechanisms","volume":"271","author":"Wu","year":"2008","journal-title":"Cancer Lett"},{"key":"key20180107210240_b15-or-32-01-0189","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.ejca.2012.06.026","article-title":"Resistance to platinum-based chemotherapy is associated with epithelial to mesenchymal transition in epithelial ovarian cancer","volume":"49","author":"Marchini","year":"2012","journal-title":"Eur J Cancer"},{"key":"key20180107210240_b16-or-32-01-0189","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.jhep.2010.12.043","article-title":"Epithelial mesenchymal transition and hedgehog signaling activation are associated with chemoresistance and invasion of hepatoma subpopulations","volume":"55","author":"Chen","year":"2011","journal-title":"J Hepatol"},{"key":"key20180107210240_b17-or-32-01-0189","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1002\/jcp.21240","article-title":"Epithelial-mesenchymal interconversions in normal ovarian surface epithelium and ovarian carcinomas: an exception to the norm","volume":"213","author":"Ahmed","year":"2007","journal-title":"J Cell Physiol"},{"key":"key20180107210240_b18-or-32-01-0189","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/0092-8674(93)90069-3","article-title":"The homeobox gene goosecoid controls cell migration in Xenopus embryos","volume":"72","author":"Niehrs","year":"1993","journal-title":"Cell"},{"key":"key20180107210240_b19-or-32-01-0189","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1126\/science.1677215","article-title":"Organizer-specific homeobox genes in Xenopus laevis embryos","volume":"253","author":"Blumberg","year":"1991","journal-title":"Science"},{"key":"key20180107210240_b20-or-32-01-0189","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1016\/0092-8674(92)90632-M","article-title":"Gastrulation in the mouse: the role of the homeobox gene goosecoid","volume":"69","author":"Blum","year":"1992","journal-title":"Cell"},{"key":"key20180107210240_b21-or-32-01-0189","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1038\/nrc822","article-title":"Epithelial-mesenchymal transitions in tumour progression","volume":"2","author":"Thiery","year":"2002","journal-title":"Nat Rev Cancer"},{"key":"key20180107210240_b22-or-32-01-0189","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1038\/nrm1175","article-title":"Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis","volume":"4","author":"Grunert","year":"2003","journal-title":"Nat Rev Mol Cell Biol"},{"key":"key20180107210240_b23-or-32-01-0189","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1002\/(SICI)1521-1878(199807)20:7<536::AID-BIES4>3.0.CO;2-I","article-title":"From cortical rotation to organizer gene expression: toward a molecular explanation of axis specification in Xenopus","volume":"20","author":"Moon","year":"1998","journal-title":"BioEssays"},{"key":"key20180107210240_b24-or-32-01-0189","doi-asserted-by":"crossref","first-page":"3038","DOI":"10.1101\/gad.9.24.3038","article-title":"Molecular mechanisms of Spemann\u2019s organizer formation: conserved growth factor synergy between Xenopus and mouse","volume":"9","author":"Watabe","year":"1995","journal-title":"Genes Dev"},{"key":"key20180107210240_b25-or-32-01-0189","doi-asserted-by":"crossref","first-page":"18969","DOI":"10.1073\/pnas.0608636103","article-title":"The Spemann organizer gene, Goosecoid, promotes tumor metastasis","volume":"103","author":"Hartwell","year":"2006","journal-title":"Proc Natl Acad Sci USA"}],"container-title":["Oncology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/or.2014.3203\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,1,7]],"date-time":"2018-01-07T21:02:55Z","timestamp":1515358975000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/or.2014.3203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,20]]},"references-count":25,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2014,5,20]]},"published-print":{"date-parts":[[2014,7]]}},"alternative-id":["10.3892\/or.2014.3203"],"URL":"https:\/\/doi.org\/10.3892\/or.2014.3203","relation":{},"ISSN":["1021-335X","1791-2431"],"issn-type":[{"value":"1021-335X","type":"print"},{"value":"1791-2431","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,20]]}}}