{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T18:43:31Z","timestamp":1791139411260,"version":"4.1.0"},"reference-count":40,"publisher":"Spandidos Publications","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.3892\/or.2014.3575","type":"journal-article","created":{"date-parts":[[2014,10,30]],"date-time":"2014-10-30T11:39:31Z","timestamp":1414669171000},"page":"347-353","source":"Crossref","is-referenced-by-count":8,"title":["Evaluation of diethylnitrosamine- or hepatitis B virus X gene-induced hepatocellular carcinoma with 18F-FDG PET\/CT: A preclinical study"],"prefix":"10.3892","volume":"33","author":[{"given":"JU HUI","family":"PARK","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JOO HYUN","family":"KANG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YONG JIN","family":"LEE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KWANG IL","family":"KIM","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"TAE SUP","family":"LEE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KYEONG MIN","family":"KIM","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JI AE","family":"PARK","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YIN OHK","family":"KO","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DAE-YEUL","family":"YU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SANG-SOEP","family":"NAHM","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"TAE JOO","family":"JEON","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YOUNG-SEO","family":"PARK","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SANG MOO","family":"LIM","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2014,10,30]]},"reference":[{"key":"key20180107213445_b1-or-33-01-0347","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1038\/nrc701","article-title":"Scaling down imaging: Molecular mapping of cancer in mice","volume":"2","author":"Weissleder","year":"2002","journal-title":"Nat Rev Cancer"},{"key":"key20180107213445_b2-or-33-01-0347","doi-asserted-by":"crossref","first-page":"164","DOI":"10.2967\/jnumed.107.045955","article-title":"Molecular-genetic imaging based on reporter gene expression","volume":"49","author":"Kang","year":"2008","journal-title":"J Nucl Med"},{"key":"key20180107213445_b3-or-33-01-0347","doi-asserted-by":"crossref","first-page":"2785","DOI":"10.1158\/1078-0432.CCR-04-2626","article-title":"Progress and promise of FDG-PET imaging for cancer patient management and oncolytic drug development","volume":"11","author":"Kelloff","year":"2005","journal-title":"Clin Cancer Res"},{"key":"key20180107213445_b4-or-33-01-0347","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1126\/science.123.3191.309","article-title":"On the origin of cancer cells","volume":"123","author":"Warburg","year":"1956","journal-title":"Science"},{"key":"key20180107213445_b5-or-33-01-0347","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1002\/nbm.856","article-title":"Tissue-specific differences in 2-f luoro-2-deoxyglucose metabolism beyond FDG-6-P: a 19F NMR spectroscopy study in the rat","volume":"16","author":"Southworth","year":"2003","journal-title":"NMR Biomed"},{"key":"key20180107213445_b6-or-33-01-0347","first-page":"333","article-title":"Evaluation of liver tumours using fluorine-18-fluorodeoxyglucose PET: characterization of tumor and assessment of effect of treatment","volume":"33","author":"Okazumi","year":"1992","journal-title":"J Nucl Med"},{"key":"key20180107213445_b7-or-33-01-0347","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/j.rcl.2005.05.008","article-title":"Applications of PET in liver imaging","volume":"43","author":"Khandani","year":"2005","journal-title":"Radiol Clin North Am"},{"key":"key20180107213445_b8-or-33-01-0347","doi-asserted-by":"crossref","first-page":"3314","DOI":"10.1111\/j.1572-0241.1999.01544.x","article-title":"Fluorine-18 FDG positron emission tomography for imaging of hepatocellular carcinoma","volume":"94","author":"Trojan","year":"1999","journal-title":"Am J Gastroenterol"},{"key":"key20180107213445_b9-or-33-01-0347","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1001\/archsurg.133.5.510","article-title":"Evaluation of benign vs malignant hepatic lesions with positron emission tomography","volume":"133","author":"Delbeke","year":"1998","journal-title":"Arch Surg"},{"key":"key20180107213445_b10-or-33-01-0347","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1016\/S0168-8278(00)80248-2","article-title":"Positron emission tomography scanning in the evaluation of hepatocellular carcinoma","volume":"32","author":"Khan","year":"2000","journal-title":"J Hepatol"},{"key":"key20180107213445_b11-or-33-01-0347","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1159\/000333265","article-title":"Diagnostic imaging of hepatocellular carcinoma: Recent Progress","volume":"81","author":"Kudo","year":"2011","journal-title":"Oncology"},{"key":"key20180107213445_b12-or-33-01-0347","first-page":"21","article-title":"Histopathology of hepatocellular carcinoma. Recent Results","volume":"190","author":"Paradis","year":"2013","journal-title":"Cancer Res"},{"key":"key20180107213445_b13-or-33-01-0347","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.ejca.2003.11.028","article-title":"Of mice and men: values and liabilities of the athymic nude mouse model in anticancer drug development","volume":"40","author":"Kelland","year":"2004","journal-title":"Eur J Cancer"},{"key":"key20180107213445_b14-or-33-01-0347","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1038\/nrc2192","article-title":"Maximizing mouse cancer models","volume":"7","author":"Frese","year":"2007","journal-title":"Nat Rev Cancer"},{"key":"key20180107213445_b15-or-33-01-0347","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1046\/j.1365-2125.1996.03748.x","article-title":"Transgenic mouse models in carcinogenesis: interaction of c-myc with transforming growth factor alpha and hepatocyte growth factor in hepatocarcinogenesis","volume":"42","author":"Thorgeirsson","year":"1996","journal-title":"Br J Clin Pharmacol"},{"key":"key20180107213445_b16-or-33-01-0347","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1158\/0008-5472.CAN-03-2123","article-title":"Hepatocarcinogenesis in mice with beta-catenin and Ha-Ras gene mutations","volume":"64","author":"Harada","year":"2004","journal-title":"Cancer Res"},{"key":"key20180107213445_b17-or-33-01-0347","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0168-8278(99)80172-X","article-title":"Incidence of hepatocellular carcinoma in transgenic mice expressing the hepatitis B virus X-protein","volume":"31","author":"Yu","year":"1999","journal-title":"J Hepatol"},{"key":"key20180107213445_b18-or-33-01-0347","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1002\/hep.21445","article-title":"Hepatitis B virus promotes hepatocarcinogenesis in transgenic mice","volume":"45","author":"Zheng","year":"2007","journal-title":"Hepatology"},{"key":"key20180107213445_b19-or-33-01-0347","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.canlet.2003.11.013","article-title":"Heterozygous p53-deficient (+\/\u2212) mice develop fewer p53-negative preneoplastic focal liver lesions in response to treatment with diethylnitrosamine than do wild-type (+ \/ +) mice","volume":"207","author":"Finnberg","year":"2004","journal-title":"Cancer Lett"},{"key":"key20180107213445_b20-or-33-01-0347","first-page":"4594","article-title":"Susceptibility to aflatoxin B-1-related primary hepatocellular carcinoma in mice and humans","volume":"63","author":"McGlynn","year":"2003","journal-title":"Cancer Res"},{"key":"key20180107213445_b21-or-33-01-0347","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1038\/labinvest.2008.91","article-title":"Activation of hepatic stellate cells is associated with cytokine expression in thioacetamide-induced hepatic fibrosis in mice","volume":"88","author":"Salguero Palacios","year":"2008","journal-title":"Lab Invest"},{"key":"key20180107213445_b22-or-33-01-0347","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1289\/ehp.77217","article-title":"Carcinogenicity studies on halogenated hydrocarbons","volume":"21","author":"Weisburger","year":"1977","journal-title":"Environ Health Perspect"},{"key":"key20180107213445_b23-or-33-01-0347","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1002\/hep.22194","article-title":"Defective DNA strand break repair causes chromosomal instability and accelerates liver carcinogenesis in mice","volume":"47","author":"Teoh","year":"2008","journal-title":"Hepatology"},{"key":"key20180107213445_b24-or-33-01-0347","doi-asserted-by":"crossref","first-page":"2682","DOI":"10.1002\/ijc.23464","article-title":"Two-dimensional differential gel electrophoresis\/analysis of diethylnitrosamine induced rat hepatocellular carcinoma","volume":"122","author":"Qi","year":"2008","journal-title":"Int J Cancer"},{"key":"key20180107213445_b25-or-33-01-0347","first-page":"1625","article-title":"Age- and sex-associated diethylnitrosamine dealkylation activity of the mouse liver and hepatocarcinogenesis","volume":"33","author":"Rao","year":"1973","journal-title":"Cancer Res"},{"key":"key20180107213445_b26-or-33-01-0347","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1126\/science.1140485","article-title":"Gender disparity in liver cancer due to sex differences in myd88-dependent IL-6 production","volume":"317","author":"Naugler","year":"2007","journal-title":"Science"},{"key":"key20180107213445_b27-or-33-01-0347","first-page":"7553","article-title":"Mouse models to study the interaction of risk factors for human liver cancer","volume":"63","author":"Sell","year":"2003","journal-title":"Cancer Res"},{"key":"key20180107213445_b28-or-33-01-0347","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1093\/toxsci\/kfs018","article-title":"Quantitative analysis of the growth kinetics of chemically induced mouse liver tumors by magnetic resonance imaging","volume":"126","author":"Schmid","year":"2012","journal-title":"Toxicol Sci"},{"key":"key20180107213445_b29-or-33-01-0347","doi-asserted-by":"crossref","first-page":"e30432","DOI":"10.1371\/journal.pone.0030432","article-title":"PET\/CT imaging of c-myc transgenic mice identifies the genotoxic n-nitroso-diethylamine as carcinogen in a short-term cancer bioassay","volume":"7","author":"Hueper","year":"2012","journal-title":"PLoS One"},{"key":"key20180107213445_b30-or-33-01-0347","doi-asserted-by":"crossref","first-page":"431","DOI":"10.2967\/jnumed.110.083956","article-title":"Total abdominal 18F-FDG uptake reflects intestinal adenoma burden in Apc mutant mice","volume":"52","author":"Heijink","year":"2011","journal-title":"J Nucl Med"},{"key":"key20180107213445_b31-or-33-01-0347","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1038\/ng1481","article-title":"Application of comparative functional genomics to identify best-fit mouse models to study human cancer","volume":"36","author":"Lee","year":"2004","journal-title":"Nat Genet"},{"key":"key20180107213445_b32-or-33-01-0347","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.jss.2007.12.748","article-title":"Mouse model of diethylnitrosamine-induced gastric cancer","volume":"148","author":"Binato","year":"2008","journal-title":"J Surg Res"},{"key":"key20180107213445_b33-or-33-01-0347","first-page":"6470","article-title":"Chronic nitrosamine ingestion in 1040 rodents: the effect of the choice of nitrosamine, the species studied and the age of starting exposure","volume":"51","author":"Gray","year":"1991","journal-title":"Cancer Res"},{"key":"key20180107213445_b34-or-33-01-0347","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.jhep.2010.10.020","article-title":"Alpha-fetoprotein-thymidine kinase-luciferase knock-in mice: a novel model for dual modality longitudinal imaging of tumorigenesis in liver","volume":"55","author":"Lu","year":"2011","journal-title":"J Hepatol"},{"key":"key20180107213445_b35-or-33-01-0347","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.canlet.2011.06.013","article-title":"Non-invasive monitoring of hepatocellular carcinoma in transgenic mouse with bioluminescent imaging","volume":"310","author":"Park","year":"2011","journal-title":"Cancer Lett"},{"key":"key20180107213445_b36-or-33-01-0347","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1002\/jgm.2648","article-title":"In vivo bioluminescent imaging of \u03b1-fetoprotein-producing hepatocellular carcinoma in the diethylnitrosamine-treated mouse using recombinant adenoviral vector","volume":"14","author":"Kim","year":"2012","journal-title":"J Gene Med"},{"key":"key20180107213445_b37-or-33-01-0347","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.canlet.2009.04.010","article-title":"Hepatitis B virus X gene is implicated in liver carcinogenesis","volume":"286","author":"Koike","year":"2009","journal-title":"Cancer Lett"},{"key":"key20180107213445_b38-or-33-01-0347","doi-asserted-by":"crossref","first-page":"3851","DOI":"10.1128\/JVI.75.8.3851-3858.2001","article-title":"Hepatitis B virus X protein acts as a tumor promoter in development of diethyl-nitrosamine-induced preneoplastic lesions","volume":"75","author":"Madden","year":"2001","journal-title":"J Virol"},{"key":"key20180107213445_b39-or-33-01-0347","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/1476-4598-9-94","article-title":"Application of magnetic resonance imaging in transgenic and chemical mouse models of hepatocellular carcinoma","volume":"9","author":"Freimuth","year":"2010","journal-title":"Mol Cancer"},{"key":"key20180107213445_b40-or-33-01-0347","first-page":"1753","article-title":"Different glucose uptake and glycolytic mechanisms between hepatocellular carcinoma and intrahepatic mass-forming cholangiocarcinoma with increased (18)F-FDG uptake","volume":"46","author":"Lee","year":"2005","journal-title":"J Nucl Med"}],"container-title":["Oncology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/or.2014.3575\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,17]],"date-time":"2023-07-17T18:18:13Z","timestamp":1689617893000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/or.2014.3575"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,30]]},"references-count":40,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2014,10,30]]},"published-print":{"date-parts":[[2015,1]]}},"alternative-id":["10.3892\/or.2014.3575"],"URL":"https:\/\/doi.org\/10.3892\/or.2014.3575","relation":{},"ISSN":["1021-335X","1791-2431"],"issn-type":[{"value":"1021-335X","type":"print"},{"value":"1791-2431","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,30]]}}}