{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T00:47:38Z","timestamp":1784594858658,"version":"3.55.0"},"reference-count":25,"publisher":"Spandidos Publications","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,4]]},"DOI":"10.3892\/or.2016.4571","type":"journal-article","created":{"date-parts":[[2016,1,18]],"date-time":"2016-01-18T09:03:18Z","timestamp":1453107798000},"page":"1916-1924","source":"Crossref","is-referenced-by-count":45,"title":["Long non-coding RNA BACE1-AS is a novel target for anisomycin-mediated suppression of ovarian cancer stem cell proliferation and invasion"],"prefix":"10.3892","volume":"35","author":[{"given":"QING","family":"CHEN","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"XINGHUI","family":"LIU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LIMIN","family":"XU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YING","family":"WANG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SUWEI","family":"WANG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"QIONG","family":"LI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YONGYI","family":"HUANG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"TE","family":"LIU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2249","published-online":{"date-parts":[[2016,1,18]]},"reference":[{"key":"key20180107210811_b1-or-35-04-1916","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1111\/j.1742-4658.2012.08589.x","article-title":"MicroRNA-199a targets CD44 to suppress the tumorigenicity and multidrug resistance of ovarian cancer-initiating cells","volume":"279","author":"Cheng","year":"2012","journal-title":"FEBS J"},{"key":"key20180107210811_b2-or-35-04-1916","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1002\/prca.200900171","article-title":"Proteomic biomarkers for overall and progression-free survival in ovarian cancer patients","volume":"4","author":"H\u00f8gdall","year":"2010","journal-title":"Proteomics Clin Appl"},{"key":"key20180107210811_b3-or-35-04-1916","first-page":"1277","article-title":"Characterization of primary ovarian cancer cells in different culture systems","volume":"23","author":"Liu","year":"2010","journal-title":"Oncol Rep"},{"key":"key20180107210811_b4-or-35-04-1916","doi-asserted-by":"crossref","first-page":"7239","DOI":"10.1007\/s13277-014-1950-9","article-title":"EZH2-specific microRNA-98 inhibits human ovarian cancer stem cell proliferation via regulating the pRb-E2F pathway","volume":"35","author":"Liu","year":"2014","journal-title":"Tumour Biol"},{"key":"key20180107210811_b5-or-35-04-1916","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1007\/s13277-014-2790-3","article-title":"MicroRNA-17 promotes normal ovarian cancer cells to cancer stem cells development via suppression of the LKB1-p53-p21\/WAF1 pathway","volume":"36","author":"Liu","year":"2015","journal-title":"Tumour Biol"},{"key":"key20180107210811_b6-or-35-04-1916","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1093\/abbs\/gmq067","article-title":"Cancer stem-like cells can be isolated with drug selection in human ovarian cancer cell line SKOV3","volume":"42","author":"Ma","year":"2010","journal-title":"Acta Biochim Biophys Sin"},{"key":"key20180107210811_b7-or-35-04-1916","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1016\/j.febslet.2013.03.023","article-title":"MicroRNA-155 is a novel suppressor of ovarian cancer-initiating cells that targets CLDN1","volume":"587","author":"Qin","year":"2013","journal-title":"FEBS Lett"},{"key":"key20180107210811_b8-or-35-04-1916","doi-asserted-by":"crossref","first-page":"4637","DOI":"10.1007\/s13277-014-1607-8","article-title":"Cisplatin targets the stromal cell-derived factor-1-CXC chemokine receptor type 4 axis to suppress metastasis and invasion of ovarian cancer-initiating cells","volume":"35","author":"Yu","year":"2014","journal-title":"Tumour Biol"},{"key":"key20180107210811_b9-or-35-04-1916","doi-asserted-by":"crossref","first-page":"4311","DOI":"10.1158\/0008-5472.CAN-08-0364","article-title":"Identification and characterization of ovarian cancer-initiating cells from primary human tumors","volume":"68","author":"Zhang","year":"2008","journal-title":"Cancer Res"},{"key":"key20180107210811_b10-or-35-04-1916","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.neuroscience.2011.07.012","article-title":"Epigenetic mechanisms of amyloid-\u03b2 production in anisomycin-treated SH-SY5Y cells","volume":"194","author":"Guo","year":"2011","journal-title":"Neuroscience"},{"key":"key20180107210811_b11-or-35-04-1916","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1093\/abbs\/gmq026","article-title":"miR-20a promotes proliferation and invasion by targeting APP in human ovarian cancer cells","volume":"42","author":"Fan","year":"2010","journal-title":"Acta Biochim Biophys Sin"},{"key":"key20180107210811_b12-or-35-04-1916","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1038\/nm1784","article-title":"Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase","volume":"14","author":"Faghihi","year":"2008","journal-title":"Nat Med"},{"key":"key20180107210811_b13-or-35-04-1916","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.3892\/mmr.2014.2351","article-title":"Attenuated ability of BACE1 to cleave the amyloid precursor protein via silencing long noncoding RNA BACE1-AS expression","volume":"10","author":"Liu","year":"2014","journal-title":"Mol Med Rep"},{"key":"key20180107210811_b14-or-35-04-1916","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S1474-4422(13)70276-X","article-title":"Targeting the \u03b2 secretase BACE1 for Alzheimer's disease therapy","volume":"13","author":"Yan","year":"2014","journal-title":"Lancet Neurol"},{"key":"key20180107210811_b15-or-35-04-1916","doi-asserted-by":"crossref","first-page":"101","DOI":"10.4149\/neo_2013_014","article-title":"Anisomycin induces apoptosis of glucocorticoid resistant acute lymphoblastic leukemia CEM-C1 cells via activation of mitogen-activated protein kinases p38 and JNK","volume":"60","author":"Liu","year":"2013","journal-title":"Neoplasma"},{"key":"key20180107210811_b16-or-35-04-1916","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.neulet.2014.07.014","article-title":"Neuroprotection by Orexin-A via HIF-1\u03b1 induction in a cellular model of Parkinson's disease","volume":"579","author":"Feng","year":"2014","journal-title":"Neurosci Lett"},{"key":"key20180107210811_b17-or-35-04-1916","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S1734-1140(13)71019-3","article-title":"Anisomycin suppresses Jurkat T cell growth by the cell cycle-regulating proteins","volume":"65","author":"Yu","year":"2013","journal-title":"Pharmacol Rep"},{"key":"key20180107210811_b18-or-35-04-1916","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/j.biochi.2012.12.002","article-title":"Anisomycin treatment enhances TRAIL-mediated apoptosis in renal carcinoma cells through the down-regulation of Bcl-2, c-FLIP(L) and Mcl-1","volume":"95","author":"Seo","year":"2013","journal-title":"Biochimie"},{"key":"key20180107210811_b19-or-35-04-1916","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1038\/aps.2012.46","article-title":"Anisomycin induces glioma cell death via down-regulation of PP2A catalytic subunit in vitro","volume":"33","author":"Li","year":"2012","journal-title":"Acta Pharmacol Sin"},{"key":"key20180107210811_b20-or-35-04-1916","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1038\/sj.embor.7400704","article-title":"Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes","volume":"7","author":"H\u00e9bert","year":"2006","journal-title":"EMBO Rep"},{"key":"key20180107210811_b21-or-35-04-1916","doi-asserted-by":"crossref","first-page":"11693","DOI":"10.1523\/JNEUROSCI.2766-05.2005","article-title":"BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions","volume":"25","author":"Laird","year":"2005","journal-title":"J Neurosci"},{"key":"key20180107210811_b22-or-35-04-1916","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0896-6273(03)00810-9","article-title":"BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease","volume":"41","author":"Ohno","year":"2004","journal-title":"Neuron"},{"key":"key20180107210811_b23-or-35-04-1916","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0969-9961(03)00104-9","article-title":"BACE1 (beta-secretase) knockout mice do not acquire compensatory gene expression changes or develop neural lesions over time","volume":"14","author":"Luo","year":"2003","journal-title":"Neurobiol Dis"},{"key":"key20180107210811_b24-or-35-04-1916","doi-asserted-by":"crossref","first-page":"30797","DOI":"10.1074\/jbc.M505249200","article-title":"Phenotypic and biochemical analyses of BACE1- and BACE2-deficient mice","volume":"280","author":"Dominguez","year":"2005","journal-title":"J Biol Chem"},{"key":"key20180107210811_b25-or-35-04-1916","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1038\/85059","article-title":"Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation","volume":"4","author":"Luo","year":"2001","journal-title":"Nat Neurosci"}],"container-title":["Oncology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/spandidos-publications.com\/10.3892\/or.2016.4571\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,1,7]],"date-time":"2018-01-07T21:08:23Z","timestamp":1515359303000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/or.2016.4571"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1,18]]},"references-count":25,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2016,1,18]]},"published-print":{"date-parts":[[2016,4]]}},"alternative-id":["10.3892\/or.2016.4571"],"URL":"https:\/\/doi.org\/10.3892\/or.2016.4571","relation":{},"ISSN":["1021-335X","1791-2431"],"issn-type":[{"value":"1021-335X","type":"print"},{"value":"1791-2431","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,1,18]]}}}