{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T18:56:40Z","timestamp":1772305000503,"version":"3.50.1"},"reference-count":42,"publisher":"Spandidos Publications","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.3892\/or.2017.5751","type":"journal-article","created":{"date-parts":[[2017,6,26]],"date-time":"2017-06-26T09:32:33Z","timestamp":1498469553000},"page":"941-948","source":"Crossref","is-referenced-by-count":46,"title":["lncRNA XIST interacts with miR-140 to modulate lung cancer growth by targeting iASPP"],"prefix":"10.3892","volume":"38","author":[{"given":"Yongjun","family":"Tang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruoxi","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"An","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pengbo","family":"Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2249","published-online":{"date-parts":[[2017,6,26]]},"reference":[{"key":"key20180107220701_b1-or-38-02-0941","article-title":"Lung cancer","volume":"2009","author":"Neville","year":"2009","journal-title":"BMJ Clin Evid"},{"key":"key20180107220701_b2-or-38-02-0941","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.path.2010.04.001","article-title":"Targeted therapies in lung cancer","volume":"3","author":"Chirieac","year":"2010","journal-title":"Surg Pathol Clin"},{"key":"key20180107220701_b3-or-38-02-0941","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0092-8674(04)00045-5","article-title":"MicroRNAs: Genomics, biogenesis, mechanism, and function","volume":"116","author":"Bartel","year":"2004","journal-title":"Cell"},{"key":"key20180107220701_b4-or-38-02-0941","doi-asserted-by":"crossref","first-page":"125094","DOI":"10.1155\/2015\/125094","article-title":"MicroRNAs as potential biomarkers in cancer: Opportunities and challenges","volume":"2015","author":"Lan","year":"2015","journal-title":"Biomed Res Int"},{"key":"key20180107220701_b5-or-38-02-0941","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1007\/s12094-014-1249-8","article-title":"Differential expression profiling of microRNAs in para-carcinoma, carcinoma and relapse human pancreatic cancer","volume":"17","author":"Lai","year":"2015","journal-title":"Clin Transl Oncol"},{"key":"key20180107220701_b6-or-38-02-0941","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.pan.2013.02.005","article-title":"MicroRNA gene polymorphisms in pancreatic cancer","volume":"13","author":"Pavlakis","year":"2013","journal-title":"Pancreatology"},{"key":"key20180107220701_b7-or-38-02-0941","doi-asserted-by":"crossref","first-page":"6704","DOI":"10.1158\/0008-5472.CAN-09-1298","article-title":"Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells","volume":"69","author":"Li","year":"2009","journal-title":"Cancer Res"},{"key":"key20180107220701_b8-or-38-02-0941","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1186\/1476-4598-9-169","article-title":"MicroRNA, hsa-miR-200c, is an independent prognostic factor in pancreatic cancer and its upregulation inhibits pancreatic cancer invasion but increases cell proliferation","volume":"9","author":"Yu","year":"2010","journal-title":"Mol Cancer"},{"key":"key20180107220701_b9-or-38-02-0941","doi-asserted-by":"crossref","first-page":"2339","DOI":"10.1245\/s10434-009-0531-4","article-title":"Involvement of CD40 targeting miR-224 and miR-486 on the progression of pancreatic ductal adenocarcinomas","volume":"16","author":"Mees","year":"2009","journal-title":"Ann Surg Oncol"},{"key":"key20180107220701_b10-or-38-02-0941","doi-asserted-by":"crossref","first-page":"S5703","DOI":"10.1158\/1538-7445.AM10-5703","article-title":"Up-regulation of miR-146a contributes to the inhibition of invasion of pancreatic cancer cells","volume":"70","author":"Li","year":"2010","journal-title":"Cancer Res"},{"key":"key20180107220701_b11-or-38-02-0941","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1002\/gcc.21941","article-title":"Both inhibition and enhanced expression of miR-31 lead to reduced migration and invasion of pancreatic cancer cells","volume":"51","author":"Laurila","year":"2012","journal-title":"Genes Chromosomes Cancer"},{"key":"key20180107220701_b12-or-38-02-0941","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/1756-9966-33-54","article-title":"miR-212 promotes pancreatic cancer cell growth and invasion by targeting the hedgehog signaling pathway receptor patched-1","volume":"33","author":"Ma","year":"2014","journal-title":"J Exp Clin Cancer Res"},{"key":"key20180107220701_b13-or-38-02-0941","doi-asserted-by":"crossref","first-page":"e87897","DOI":"10.1371\/journal.pone.0087897","article-title":"MiR-196a promotes pancreatic cancer progression by targeting nuclear factor kappa-B-inhibitor alpha","volume":"9","author":"Huang","year":"2014","journal-title":"PLoS One"},{"key":"key20180107220701_b14-or-38-02-0941","doi-asserted-by":"crossref","first-page":"2589","DOI":"10.1038\/onc.2013.226","article-title":"Downregulation of miR-140 promotes cancer stem cell formation in basal-like early stage breast cancer","volume":"33","author":"Li","year":"2014","journal-title":"Oncogene"},{"key":"key20180107220701_b15-or-38-02-0941","doi-asserted-by":"crossref","first-page":"2957","DOI":"10.1016\/j.febslet.2014.05.048","article-title":"miR-140-5p suppresses BMP2-mediated osteogenesis in undifferentiated human mesenchymal stem cells","volume":"588","author":"Hwang","year":"2014","journal-title":"FEBS Lett"},{"key":"key20180107220701_b16-or-38-02-0941","doi-asserted-by":"crossref","first-page":"4065","DOI":"10.1038\/onc.2009.274","article-title":"Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells","volume":"28","author":"Song","year":"2009","journal-title":"Oncogene"},{"key":"key20180107220701_b17-or-38-02-0941","first-page":"12845","article-title":"MicroRNA-140-3p inhibits proliferation, migration and invasion of lung cancer cells by targeting ATP6AP2","volume":"8","author":"Kong","year":"2015","journal-title":"Int J Clin Exp Pathol"},{"key":"key20180107220701_b18-or-38-02-0941","doi-asserted-by":"crossref","first-page":"e73604","DOI":"10.1371\/journal.pone.0073604","article-title":"miR-140 suppresses tumor growth and metastasis of non-small cell lung cancer by targeting insulin-like growth factor 1 receptor","volume":"8","author":"Yuan","year":"2013","journal-title":"PLoS One"},{"key":"key20180107220701_b19-or-38-02-0941","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/nature11233","article-title":"Landscape of transcription in human cells","volume":"489","author":"Djebali","year":"2012","journal-title":"Nature"},{"key":"key20180107220701_b20-or-38-02-0941","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1016\/j.eururo.2013.12.003","article-title":"Long noncoding RNA in prostate, bladder, and kidney cancer","volume":"65","author":"Martens-Uzunova","year":"2014","journal-title":"Eur Urol"},{"key":"key20180107220701_b21-or-38-02-0941","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.cell.2009.02.006","article-title":"Evolution and functions of long noncoding RNAs","volume":"136","author":"Ponting","year":"2009","journal-title":"Cell"},{"key":"key20180107220701_b22-or-38-02-0941","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1007\/s00432-014-1699-y","article-title":"An emerging understanding of long noncoding RNAs in kidney cancer","volume":"140","author":"Zhou","year":"2014","journal-title":"J Cancer Res Clin Oncol"},{"key":"key20180107220701_b23-or-38-02-0941","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/978-1-4939-3378-5_21","article-title":"Analyzing miRNA-lncRNA interactions","volume":"1402","author":"Paraskevopoulou","year":"2016","journal-title":"Methods Mol Biol"},{"key":"key20180107220701_b24-or-38-02-0941","doi-asserted-by":"crossref","first-page":"561","DOI":"10.2478\/s11658-014-0212-6","article-title":"Regulation of lncRNA expression","volume":"19","author":"Wu","year":"2014","journal-title":"Cell Mol Biol Lett"},{"key":"key20180107220701_b25-or-38-02-0941","doi-asserted-by":"crossref","first-page":"3766","DOI":"10.1111\/febs.12902","article-title":"lncRNA H19\/miR-675 axis represses prostate cancer metastasis by targeting TGFBI","volume":"281","author":"Zhu","year":"2014","journal-title":"FEBS J"},{"key":"key20180107220701_b26-or-38-02-0941","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1159\/000430309","article-title":"The interaction between miR-141 and lncRNA-H19 in regulating cell proliferation and migration in gastric cancer","volume":"36","author":"Zhou","year":"2015","journal-title":"Cell Physiol Biochem"},{"key":"key20180107220701_b27-or-38-02-0941","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1038\/nrc1840","article-title":"Oncomirs - microRNAs with a role in cancer","volume":"6","author":"Esquela-Kerscher","year":"2006","journal-title":"Nat Rev Cancer"},{"key":"key20180107220701_b28-or-38-02-0941","first-page":"R40","article-title":"MicroRNAs in cell proliferation, cell death, and tumorigenesis","volume":"96","author":"Hwang","year":"2007","journal-title":"Br J Cancer"},{"key":"key20180107220701_b29-or-38-02-0941","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.cell.2004.12.035","article-title":"Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets","volume":"120","author":"Lewis","year":"2005","journal-title":"Cell"},{"key":"key20180107220701_b30-or-38-02-0941","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1042\/CS20150230","article-title":"Role of miR-140 in embryonic bone development and cancer","volume":"129","author":"Green","year":"2015","journal-title":"Clin Sci"},{"key":"key20180107220701_b31-or-38-02-0941","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.canlet.2014.12.051","article-title":"Knockdown of long non-coding RNA XIST exerts tumor-suppressive functions in human glioblastoma stem cells by up-regulating miR-152","volume":"359","author":"Yao","year":"2015","journal-title":"Cancer Lett"},{"key":"key20180107220701_b32-or-38-02-0941","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1002\/hep.26315","article-title":"MicroRNA-140-5p suppresses tumor growth and metastasis by targeting transforming growth factor \u03b2 receptor 1 and fibroblast growth factor 9 in hepatocellular carcinoma","volume":"58","author":"Yang","year":"2013","journal-title":"Hepatology"},{"key":"key20180107220701_b33-or-38-02-0941","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/978-1-4939-1538-5_25","article-title":"Targeting microRNAs to withstand cancer metastasis","volume":"1218","author":"Profumo","year":"2015","journal-title":"Methods Mol Biol"},{"key":"key20180107220701_b34-or-38-02-0941","doi-asserted-by":"crossref","first-page":"2963","DOI":"10.3892\/or.2015.3935","article-title":"Screening of differential microRNA expression in gastric signet ring cell carcinoma and gastric adenocarcinoma and target gene prediction","volume":"33","author":"Chen","year":"2015","journal-title":"Oncol Rep"},{"key":"key20180107220701_b35-or-38-02-0941","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1186\/1471-2407-10-694","article-title":"iASPP is over-expressed in human non-small cell lung cancer and regulates the proliferation of lung cancer cells through a p53 associated pathway","volume":"10","author":"Chen","year":"2010","journal-title":"BMC Cancer"},{"key":"key20180107220701_b36-or-38-02-0941","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1016\/j.leukres.2009.04.037","article-title":"iASPP, a potential drug target in cancer therapy","volume":"33","author":"Gillotin","year":"2009","journal-title":"Leuk Res"},{"key":"key20180107220701_b37-or-38-02-0941","doi-asserted-by":"crossref","first-page":"125","DOI":"10.3727\/096504011X12935427587768","article-title":"iASPP is important for bladder cancer cell proliferation","volume":"19","author":"Liu","year":"2011","journal-title":"Oncol Res"},{"key":"key20180107220701_b38-or-38-02-0941","doi-asserted-by":"crossref","first-page":"2816","DOI":"10.1096\/fj.13-244632","article-title":"Oncogene iASPP enhances self-renewal of hematopoietic stem cells and facilitates their resistance to chemotherapy and irradiation","volume":"28","author":"Jia","year":"2014","journal-title":"FASEB J"},{"key":"key20180107220701_b39-or-38-02-0941","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.arcmed.2010.02.007","article-title":"MicroRNA-34a: A novel tumor suppressor in p53-mutant glioma cell line U251","volume":"41","author":"Luan","year":"2010","journal-title":"Arch Med Res"},{"key":"key20180107220701_b40-or-38-02-0941","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s11010-011-1052-6","article-title":"MicroRNA-21: A ubiquitously expressed pro-survival factor in cancer and other diseases","volume":"360","author":"Li","year":"2012","journal-title":"Mol Cell Biochem"},{"key":"key20180107220701_b41-or-38-02-0941","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/s00401-011-0924-x","article-title":"MicroRNA-182 promotes leptomeningeal spread of non-sonic hedgehog-medulloblastoma","volume":"123","author":"Bai","year":"2012","journal-title":"Acta Neuropathol"},{"key":"key20180107220701_b42-or-38-02-0941","first-page":"2","article-title":"ASPP and iASPP: Implication in cancer development and progression","volume":"61","author":"Li","year":"2015","journal-title":"Cell Mol Biol"}],"container-title":["Oncology Reports"],"original-title":[],"language":"en","deposited":{"date-parts":[[2018,1,7]],"date-time":"2018-01-07T22:08:37Z","timestamp":1515362917000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.spandidos-publications.com\/10.3892\/or.2017.5751"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":42,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2017,6,26]]},"published-print":{"date-parts":[[2017,2]]}},"alternative-id":["10.3892\/or.2017.5751"],"URL":"https:\/\/doi.org\/10.3892\/or.2017.5751","relation":{},"ISSN":["1021-335X","1791-2431"],"issn-type":[{"value":"1021-335X","type":"print"},{"value":"1791-2431","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2]]}}}