{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T13:37:16Z","timestamp":1765546636491,"version":"3.40.5"},"reference-count":0,"publisher":"Pensoft Publishers","issue":"2","license":[{"start":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T00:00:00Z","timestamp":1593475200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FM"],"abstract":"<jats:p>Large-cell neuroendocrine carcinoma of the endometrium is an insufficiently researched aggressive tumor with a short survival regard&amp;shy;less of the treatment type.<\/jats:p>\n          <jats:p>We present here the 38<jats:sup>th <\/jats:sup>consecutive case of literature reported cases of large cell neuroendocrine carcinoma of the endometrium (posi&amp;shy;tive for synaptophysin, CD56, chromogranin A, p53, and Vimentin) found in the myomatous uterus of a 76-year-old woman.<\/jats:p>\n          <jats:p>We also describe in the study the morphological algorithm for differentiation of malignant blastomas with small (under 10 %) neuro-endocrinal component.<\/jats:p>\n          <jats:p>Accumulated clinical and morphological evidence raises the question whether the large-cell and the small-cell neuroendocrine carcino&amp;shy;mas are just different variations according to their histology and topical occurrence (uterine body\/cervix) or they are just independent forms with their respective clinical signs, morphology, treatment, and prognosis.<\/jats:p>","DOI":"10.3897\/folmed.62.e49815","type":"journal-article","created":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T18:18:43Z","timestamp":1593541123000},"page":"412-417","source":"Crossref","is-referenced-by-count":3,"title":["Large-cell Neuroendocrine Carcinoma of the Endometrium in Myomatous Uterus"],"prefix":"10.3897","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7095-3411","authenticated-orcid":true,"given":"Spasimir T.","family":"Shopov","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benyamin L.","family":"Anavi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dobrin K.","family":"Krastev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2258","published-online":{"date-parts":[[2020,6,30]]},"container-title":["Folia Medica"],"original-title":[],"link":[{"URL":"https:\/\/foliamedica.bg\/article\/49815\/download\/pdf\/","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/foliamedica.bg\/article\/49815\/download\/xml\/","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/foliamedica.bg\/article_preview.php?id=49815&skip_redirect=1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T18:18:43Z","timestamp":1593541123000},"score":1,"resource":{"primary":{"URL":"https:\/\/foliamedica.bg\/article\/49815\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,30]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020,6,30]]}},"URL":"https:\/\/doi.org\/10.3897\/folmed.62.e49815","relation":{},"ISSN":["1314-2143","0204-8043"],"issn-type":[{"type":"electronic","value":"1314-2143"},{"type":"print","value":"0204-8043"}],"subject":[],"published":{"date-parts":[[2020,6,30]]}}}