{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:23:43Z","timestamp":1777501423889,"version":"3.51.4"},"reference-count":0,"publisher":"Pensoft Publishers","issue":"1","license":[{"start":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T00:00:00Z","timestamp":1646006400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FM"],"abstract":"<jats:p><jats:bold>Introduction:<\/jats:bold><jats:italic>Plumbago zeylanica<\/jats:italic> grows widely in many tropical countries. In Indonesia, this plant, known as Daun Encok, has some beneficial effects on human health.&amp;nbsp;<\/jats:p>\n          <jats:p><jats:bold>Aim: <\/jats:bold>This exploration study aimed to identify the plumbagin compound in <jats:italic>P. zeylanica<\/jats:italic> roots from Indonesia.&amp;nbsp;<\/jats:p>\n          <jats:p><jats:bold>Materials and methods:<\/jats:bold> Dried roots of <jats:italic>P. zeylanica<\/jats:italic> were manually ground and then the powder was macerated using ethanol and chloroform for 24 hours at room temperature. All extracts of <jats:italic>P. zeylanica<\/jats:italic> were then analyzed using gas chromatography-mass spectrometry (GC-MS). Plumbagin concentration was measured by comparing the extract with pure plumbagin.<\/jats:p>\n          <jats:p><jats:bold>Results: <\/jats:bold>GC-MS analysis of ethanol extract and chloroform extract of <jats:italic>P. zeylanica<\/jats:italic> roots showed the presence of plumbagin as the highest peak. Plumbagin concentration in ethanol extract was 13%, while in chloroform extract it was 81%.<\/jats:p>\n          <jats:p><jats:bold>Conclusions: <\/jats:bold>The chloroform extract of <jats:italic>P. zeylanica<\/jats:italic> root from Indonesia demonstrates a higher concentration of plumbagin compared to ethanol extract.&amp;nbsp;<\/jats:p>","DOI":"10.3897\/folmed.64.e58086","type":"journal-article","created":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T12:36:09Z","timestamp":1646138169000},"page":"96-102","source":"Crossref","is-referenced-by-count":4,"title":["Phytochemical evaluation of Plumbago zeylanica roots from Indonesia and assessment of its plumbagin concentration"],"prefix":"10.3897","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3936-3883","authenticated-orcid":true,"given":"Mitayani","family":"Purwoko","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harijono","family":"Kario Sentono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bambang","family":"Purwanto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dono","family":"Indarto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2258","published-online":{"date-parts":[[2022,2,28]]},"container-title":["Folia Medica"],"original-title":[],"link":[{"URL":"https:\/\/foliamedica.bg\/article\/58086\/download\/pdf\/","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/foliamedica.bg\/article\/58086\/download\/xml\/","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/foliamedica.bg\/article_preview.php?id=58086&skip_redirect=1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T12:36:10Z","timestamp":1646138170000},"score":1,"resource":{"primary":{"URL":"https:\/\/foliamedica.bg\/article\/58086\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,28]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,2,28]]}},"URL":"https:\/\/doi.org\/10.3897\/folmed.64.e58086","relation":{},"ISSN":["1314-2143","0204-8043"],"issn-type":[{"value":"1314-2143","type":"electronic"},{"value":"0204-8043","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2,28]]}}}