{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T08:12:27Z","timestamp":1769847147395,"version":"3.49.0"},"reference-count":0,"publisher":"Pensoft Publishers","issue":"2","license":[{"start":{"date-parts":[[2023,4,30]],"date-time":"2023-04-30T00:00:00Z","timestamp":1682812800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FM"],"abstract":"<jats:p>Autoimmune polyglandular syndromes (APS) are rare disorders characterized by the coexistence of endocrine and non-endocrine dysfunctions mediated by autoimmune mechanisms. Autoimmune polyglandular syndrome type 1 is defined as coexistence of chronic mucocutaneous candidiasis, hypoparathyroidism, and autoimmune adrenal insufficiency. Addison&amp;rsquo;s disease as the obligatory component is potentially life threatening.<\/jats:p>\n          <jats:p>Herein, we demonstrate a case of a 44-year-old woman with APS-1 (hypoparathyroidism, adrenal insufficiency, hypergonadotropic hypogonadism) and SARS-CoV-2-induced adrenal crisis. The patient presented with the typical manifestations of hypotensive shock, electrolyte disturbances of hyponatremia and hyperkalemia, and hypoglycaemia.<\/jats:p>\n          <jats:p>Our case report illustrates the increased risk of severe course of COVID-19 in APS-1 syndrome patients along with heightened exposure to medical complications. The case reinforced the significance of a timely diagnosis, appropriate treatment, and education of patients with such a rare condition like APS-1.<\/jats:p>","DOI":"10.3897\/folmed.65.e76245","type":"journal-article","created":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T15:04:33Z","timestamp":1683212673000},"page":"305-310","source":"Crossref","is-referenced-by-count":2,"title":["SARS-CoV-2-induced adrenal crisis in a patient with autoimmune polyglandular syndrome type 1: case report"],"prefix":"10.3897","volume":"65","author":[{"given":"Presiyana","family":"Nyagolova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitko","family":"Mitkov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7198-3532","authenticated-orcid":true,"given":"Lyubomir","family":"Sapundzhiev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2258","published-online":{"date-parts":[[2023,4,30]]},"container-title":["Folia Medica"],"original-title":[],"link":[{"URL":"https:\/\/foliamedica.bg\/article\/76245\/download\/pdf\/","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/foliamedica.bg\/article\/76245\/download\/xml\/","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/foliamedica.bg\/article\/76245\/download\/pdf\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T15:04:34Z","timestamp":1683212674000},"score":1,"resource":{"primary":{"URL":"https:\/\/foliamedica.bg\/article\/76245\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,30]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,4,30]]}},"URL":"https:\/\/doi.org\/10.3897\/folmed.65.e76245","relation":{},"ISSN":["1314-2143","0204-8043"],"issn-type":[{"value":"1314-2143","type":"electronic"},{"value":"0204-8043","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4,30]]}}}