{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T11:47:31Z","timestamp":1747223251478,"version":"3.40.5"},"reference-count":11,"publisher":"Pensoft Publishers","issue":"4","license":[{"start":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T00:00:00Z","timestamp":1693440000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FM"],"abstract":"<jats:p>A combination of laryngeal carcinoma and subsequent primary lung cancer is rare yet important in terms of therapeutic strategy and prognosis.<\/jats:p>\n          <jats:p>We present a case of primary squamous cell laryngeal carcinoma treated with laryngectomy and chemoradiation therapy. One year later, the patient developed metachronous squamous cell carcinoma of the lung and underwent left pneumonectomy.<\/jats:p>\n          <jats:p>A second primary lung cancer after laryngeal cancer presents a significant challenge for surgeons, oncologists, and radiotherapists. The differentiation between lung metastasis and primary lung cancer is of paramount importance for the correct therapeutic strategy and prognosis.<\/jats:p>","DOI":"10.3897\/folmed.65.e85074","type":"journal-article","created":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T06:17:40Z","timestamp":1693462660000},"page":"671-674","source":"Crossref","is-referenced-by-count":1,"title":["A metachronous second primary lung cancer after laryngectomy for laryngeal carcinoma"],"prefix":"10.3897","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2068-5724","authenticated-orcid":true,"given":"Georgi","family":"Yankov","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3884-3057","authenticated-orcid":true,"given":"Magdalena","family":"Alexieva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefka","family":"Yankova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4410-6515","authenticated-orcid":true,"given":"Evgeni","family":"Mekov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2258","published-online":{"date-parts":[[2023,8,31]]},"reference":[{"key":"85074_B1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.4552"},{"key":"85074_B2","unstructured":"2. Bagri PK, Singh D, Singhal MK, et al. Double primary malignancies: a clinical and pathological analysis report from a regional cancer institute in India. Iran J Cancer Prev 2014; 7(2):66\u201372."},{"key":"85074_B3","doi-asserted-by":"crossref","unstructured":"3. Akhtar J, Bhargava R, Shameem M, et al. Second primary lung cancer with glottic laryngeal cancer as index tumor - a case report. Case Rep Oncol 2010; 3(1):35\u20139.","DOI":"10.1159\/000279320"},{"key":"85074_B4","doi-asserted-by":"crossref","unstructured":"4. Adams M, Gray G, Kelly A, et al. Second primary lung cancer following laryngeal cancer: Retrospective study of incidence and multivariate analysis of risk factors in 209 patients. J Laryngol Otol 2019; 133(11):974\u20139.","DOI":"10.1017\/S0022215119002147"},{"key":"85074_B5","doi-asserted-by":"crossref","unstructured":"5. Holland J, Arsanjani A, Liem B, et al. Second malignancies in early stage laryngeal carcinoma patients treated with radiotherapy. J Laryngol Otol 2002; 116(3):190\u20133.","DOI":"10.1258\/0022215021910500"},{"key":"85074_B6","unstructured":"6. Gao Y, Wang L, Zhang D. [Second primary lung cancer in laryngeal cancer patients: report on 36 cases]. Zhonghua Zhong liu za zhi [Chinese Journal of Oncology] 2001; 23(4):341\u20133 [Chinese]."},{"key":"85074_B7","doi-asserted-by":"crossref","unstructured":"7. Silvestri F, Bussani R, Cosatti, et al. High relative risk of a second pulmonary cancer in patients affected by laryngeal cancer: Differences by specific site of occurrence and lung cancer histotype. The Laryngoscope 1994; 104:222\u20135.","DOI":"10.1288\/00005537-199402000-00017"},{"key":"85074_B8","doi-asserted-by":"crossref","unstructured":"8. Kim EK, Kim JY, Kim BM, et al. Multiple primary malignancies of laryngeal cancer, small cell lung cancer and squamous cell lung cancer in a patient: how to approach MPMs. BMJ Case Rep 2017; 2017:bcr2016216305.","DOI":"10.1136\/bcr-2016-216305"},{"key":"85074_B9","doi-asserted-by":"crossref","unstructured":"9. Akhtar J, Bhargava R, Shameem M, et al. Second primary lung cancer with glottic laryngeal cancer as index tumor - a case report. Case Rep Oncol 2010; 3(1):35\u20139.","DOI":"10.1159\/000279320"},{"key":"85074_B10","doi-asserted-by":"crossref","unstructured":"10. Geurts T, Klomp H, Burgers S, et al. Resection of secondary pulmonary malignancies in head and neck cancer patients. J Laryngol Otol 2010; 124(12):1278\u201383.","DOI":"10.1017\/S0022215110001064"},{"key":"85074_B11","doi-asserted-by":"crossref","unstructured":"11. Haughey BH, Arfken CL, Gates GA, et al. Meta-analysis of second malignant tumors in head and neck cancer: the case for an endoscopic screening protocol. Ann Otol Rhinol Laryngol 1992; 101(2 Pt 1):105\u201312.","DOI":"10.1177\/000348949210100201"}],"container-title":["Folia Medica"],"original-title":[],"link":[{"URL":"https:\/\/foliamedica.bg\/article\/85074\/download\/pdf\/","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/foliamedica.bg\/article\/85074\/download\/xml\/","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/foliamedica.bg\/article_preview.php?id=85074&skip_redirect=1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T06:17:47Z","timestamp":1693462667000},"score":1,"resource":{"primary":{"URL":"https:\/\/foliamedica.bg\/article\/85074\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,31]]},"references-count":11,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,8,31]]}},"URL":"https:\/\/doi.org\/10.3897\/folmed.65.e85074","relation":{},"ISSN":["1314-2143","0204-8043"],"issn-type":[{"type":"electronic","value":"1314-2143"},{"type":"print","value":"0204-8043"}],"subject":[],"published":{"date-parts":[[2023,8,31]]}}}