{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:46:57Z","timestamp":1753894017122,"version":"3.41.2"},"reference-count":15,"publisher":"Pensoft Publishers","issue":"1","license":[{"start":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T00:00:00Z","timestamp":1740355200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FM"],"abstract":"<jats:p>Cerebral salt wasting syndrome is described as a hyponatremic condition in the context of a central nervous system injury. It is caused by a renal loss of sodium, and the primary distinguishing factor among similar conditions, such as the syndrome of inappropriate antidiuretic hormone secretion, is a reduction in the extracellular fluid volume. We describe here the case of a young adult who suffered brain injuries as a result of a gunshot and developed cerebral salt wasting syndrome during his in-hospital stay. Any type of cerebral attack can lead to hyponatraemic syndrome, but the most common are subarachnoid hemorrhages and neurological and meningeal tuberculosis infections. Treatment of the cerebral salt wasting syndrome leads to both hypovolemia and hyponatremia correction. The first line of management included hydric reposition with saline solution, either isotonic or hypertonic, depending on the severity of the symptoms.<\/jats:p>","DOI":"10.3897\/folmed.67.e130280","type":"journal-article","created":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T13:57:46Z","timestamp":1740405466000},"source":"Crossref","is-referenced-by-count":1,"title":["Cerebral salt wasting syndrome in a patient who suffered a gunshot traumatic head injury: a case report"],"prefix":"10.3897","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-5990-106X","authenticated-orcid":true,"given":"Alejandro","family":"Rojas-Urrea","sequence":"first","affiliation":[{"name":"Hospital Regional de la Orinoquia, Yopal, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6615-1413","authenticated-orcid":true,"given":"Daniela","family":"Arias-Mari\u00f1o","sequence":"additional","affiliation":[{"name":"Hospital Regional de la Orinoquia, Yopal, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9557-0900","authenticated-orcid":true,"given":"Lorena","family":"Garc\u00eda-Agudelo","sequence":"additional","affiliation":[{"name":"Hospital Regional de la Orinoquia, Yopal, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2573-0013","authenticated-orcid":true,"given":"Ivan Camilo","family":"Gonzalez-Calderon","sequence":"additional","affiliation":[{"name":"Hospital Regional de la Orinoquia, Yopal, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2258","published-online":{"date-parts":[[2025,2,24]]},"reference":[{"key":"130280_B1","unstructured":"1. Tenny S, Thorell W. Cerebral salt wasting syndrome. Stat Pearls 2023."},{"key":"130280_B2","doi-asserted-by":"crossref","unstructured":"2. Cerd\u00e0-Esteve M, Cuadrado-Godia E, Chillaron JJ, et al. Cerebral salt wasting syndrome: review. Eur J Intern Med 2008; 19(4):249\u201354.","DOI":"10.1016\/j.ejim.2007.06.019"},{"key":"130280_B3","unstructured":"3. Peters JP, Welt LG, Sims EA, et al. A salt-wasting syndrome associated with cerebral disease. Trans Assoc Am Physicians 1950; 63:57\u201364."},{"key":"130280_B4","doi-asserted-by":"crossref","unstructured":"4. Cui H, He G, Yang S, et al. Inappropriate antidiuretic hormone secretion and cerebral salt-wasting syndromes in neurological patients. Front Neurosci 2019; 13:1170.","DOI":"10.3389\/fnins.2019.01170"},{"key":"130280_B5","doi-asserted-by":"crossref","unstructured":"5. Oh H, Seo W. An integrative review of cerebral salt wasting syndrome. J Neurosci Nurs 2020; 52(6):289\u2013294.","DOI":"10.1097\/JNN.0000000000000548"},{"key":"130280_B6","doi-asserted-by":"crossref","unstructured":"6. Misra UK, Kalita J, Bhoi SK, et al. A study of hyponatremia in tuberculous meningitis. J Neurol Sci 2016; 367:152\u20137.","DOI":"10.1016\/j.jns.2016.06.004"},{"key":"130280_B7","doi-asserted-by":"crossref","unstructured":"7. Bouchlarhem A, Haddar L, Berrichi H, et al. Cerebral salt wasting syndrome (CSW): An unusual cause of hypovolemia after spontaneous cerebral hemorrhage successfully treated with fludrocortisone. Radiol Case Rep 2021; 17(1):106\u2013110.","DOI":"10.1016\/j.radcr.2021.08.049"},{"key":"130280_B8","doi-asserted-by":"crossref","unstructured":"8. Mullaguri N, Omer T, George P, et al. Refractory polyuria secondary to cerebral salt wasting successfully treated with DDAVP and hypertonic saline. Interdiscip Neurosurg 2020; 22:100814.","DOI":"10.1016\/j.inat.2020.100814"},{"key":"130280_B9","doi-asserted-by":"crossref","unstructured":"9. Mohamed H, Shorten G. Distinguishing cerebral salt wasting syndrome and syndrome of inappropriate ADH in a patient with traumatic brain injury. BMJ Case Rep 2021; 14(3):e237027.","DOI":"10.1136\/bcr-2020-237027"},{"key":"130280_B10","doi-asserted-by":"crossref","unstructured":"10. Rajagopal R, Swaminathan G, Nair S, et al. Hyponatremia in traumatic brain injury: a practical management protocol. World Neurosurg 2017; 108:529\u201333.","DOI":"10.1016\/j.wneu.2017.09.013"},{"key":"130280_B11","doi-asserted-by":"crossref","unstructured":"11. Taylor P, Dehbozorgi S, Tabasum A, et al. Cerebral salt wasting following traumatic brain injury. Endocrinol Diabetes Metab Case Rep 2017; 2017:16-0142.","DOI":"10.1530\/EDM-16-0142"},{"key":"130280_B12","doi-asserted-by":"crossref","unstructured":"12. Makoveev SA, Grudina ES, Tsarionova DV, et al. Combination of central diabetes insipidus and salt wasting syndrome in a patient with severe traumatic brain injury. Russ J Anesthesiol Reanimatol 2024; (1):57\u201363.","DOI":"10.17116\/anaesthesiology202401157"},{"key":"130280_B13","doi-asserted-by":"crossref","unstructured":"13. Costa MM, Esteves C, Castedo JL, et al. A challenging coexistence of central diabetes insipidus and cerebral salt wasting syndrome: a case report. J Med Case Rep 2018; 12(1):212.","DOI":"10.1186\/s13256-018-1678-z"},{"key":"130280_B14","doi-asserted-by":"crossref","unstructured":"14. Shah A, Sabir S, Artani M, et al. Significance of hyponatremia as an independent factor in predicting short-term mortality in patients with hemorrhagic stroke. Cureus 2019; 11(4):e4549.","DOI":"10.7759\/cureus.4549"},{"key":"130280_B15","doi-asserted-by":"crossref","unstructured":"15. Chendrasekhar A, Chow PT, Cohen D, et al. Cerebral salt wasting in traumatic brain injury is associated with increased morbidity and mortality. 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