{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T09:33:01Z","timestamp":1786613581706,"version":"build-2736575974"},"reference-count":15,"publisher":"Pensoft Publishers","issue":"4","license":[{"start":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T00:00:00Z","timestamp":1786579200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FM"],"abstract":"<jats:p>\n                    <jats:bold>Abstract<\/jats:bold>\n                  <\/jats:p>\n                  <jats:p>We describe a 57-year-old man who had initial isolated weakness in the deep finger flexors of his non-dominant hand, followed by quadriceps weakness and wasting a year later. Despite the distribution specific for sporadic inclusion body myositis (s-IBM) and early myogenic abnormalities found in deep finger flexors, the case was initially misdiagnosed as polymyositis based on the initial biopsy results, which revealed endomysial inflammation with partial invasion\/compression of non-necrotic fiber, without rimmed vacuoles. As a result, the patient received unnecessary treatment, including immunosuppressants, which caused serious side effects. The second biopsy revealed rimmed vacuoles, and the diagnosis of s-IBM was confirmed.<\/jats:p>\n                  <jats:p>The role of clinical, pathological, and electrophysiological features for early diagnosis of s-IBM and differentiation from PM is discussed.<\/jats:p>","DOI":"10.3897\/folmed.68.e155323","type":"journal-article","created":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T09:25:15Z","timestamp":1786613115000},"source":"Crossref","is-referenced-by-count":0,"title":["Sporadic inclusion body myositis: overreliance on histology may lead to misdiagnosis"],"prefix":"10.3897","volume":"68","author":[{"given":"Behidzhe","family":"Sadarzanska-Terzieva","sequence":"first","affiliation":[{"name":"Department of Clinical and Medico-Biological Sciences at Medical University of Sofia, Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Plamen","family":"Tzvetanov","sequence":"additional","affiliation":[{"name":"Department of Clinical and Medico-Biological Sciences at Medical University of Sofia, Sofia, Bulgaria"},{"name":"Research Institute at Medical University of Pleven, Pleven, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rossen","family":"Rousseff","sequence":"additional","affiliation":[{"name":"Medical Centre Medica 2005, Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2258","published-online":{"date-parts":[[2026,8,13]]},"reference":[{"key":"155323_B1"},{"key":"155323_B2"},{"key":"155323_B3"},{"key":"155323_B4","doi-asserted-by":"crossref","unstructured":"Vattemi G, Mirabella M, Guglielmi V, et al. Muscle biopsy features of idiopathic inflammatory myopathies and differential diagnosis. Autoimmun Highlights 2014; 5:77\u201385.","DOI":"10.1007\/s13317-014-0062-2"},{"key":"155323_B5","doi-asserted-by":"crossref","unstructured":"Lee E, Chahin N. Is a muscle biopsy necessary for the diagnosis of inclusion body myositis (IBM)? (P07.223). Neurology 2012; 78:P07.223","DOI":"10.1212\/WNL.78.1_MeetingAbstracts.P07.223"},{"key":"155323_B6"},{"key":"155323_B7"},{"key":"155323_B8","doi-asserted-by":"crossref","unstructured":"Brady S, Squier W, Hilton-Jones D. Clinical assessment determines the diagnosis of inclusion body myositis independently of pathological features. J Neurol Neurosurg Psychiatry 2013; 84:1240\u20136.","DOI":"10.1136\/jnnp-2013-305690"},{"key":"155323_B9"},{"key":"155323_B10"},{"key":"155323_B11","unstructured":"Fredericks EJ. Electromyography in polymyositis and dermatomyositis. Muscle Nerve 1994; 17:1235\u20136."},{"key":"155323_B12"},{"key":"155323_B13","doi-asserted-by":"crossref","unstructured":"Hokkoku K, Sonoo M, Higashihara M, et al. Electromyography of the flexor digitorum profundus muscle is useful for the diagnosis of inclusion body myositis. Muscle Nerve 2012; 46:181\u20136.","DOI":"10.1002\/mus.23292"},{"key":"155323_B14"},{"key":"155323_B15"}],"container-title":["Folia Medica"],"original-title":[],"link":[{"URL":"https:\/\/foliamedica.bg\/article\/155323\/download\/pdf\/","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/foliamedica.bg\/article\/155323\/download\/xml\/","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/foliamedica.bg\/article_preview.php?id=155323&skip_redirect=1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T09:25:20Z","timestamp":1786613120000},"score":1,"resource":{"primary":{"URL":"https:\/\/foliamedica.bg\/article\/155323\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,13]]},"references-count":15,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2026,8,13]]}},"URL":"https:\/\/doi.org\/10.3897\/folmed.68.e155323","relation":{},"ISSN":["1314-2143","0204-8043"],"issn-type":[{"value":"1314-2143","type":"electronic"},{"value":"0204-8043","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8,13]]},"article-number":"e155323"}}