{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T17:52:26Z","timestamp":1775152346664,"version":"3.50.1"},"reference-count":36,"publisher":"Pensoft Publishers","issue":"2","license":[{"start":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T00:00:00Z","timestamp":1775174400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FM"],"abstract":"<jats:p>\n                    <jats:bold>Introduction<\/jats:bold>\n                    : Nickel allergy is among the most common contact hypersensitivities worldwide. It affects women predominantly. This study examined whether female nickel-sensitized patients exhibit reversible changes in pulmonary function following a period of nickel avoidance.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Aim<\/jats:bold>\n                    : To evaluate pulmonary functional parameters (PFPs) in female patients with nickel sensitization and assess changes after nickel avoidance.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Materials and methods<\/jats:bold>\n                    : Twelve adult women with confirmed nickel hypersensitivity underwent spirometry before and after a 3\u2011month nickel avoidance program. Measured parameters included forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), peak expiratory flow (PEF), and the FEV1\/FVC ratio. Paired-sample tests and effect sizes were calculated.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results<\/jats:bold>\n                    : All indices changed significantly after avoidance. FVC increased from 2.7\u00b10.7 L to 3.4\u00b10.5 L [t(11)=\u22125.50,\n                    <jats:italic>p<\/jats:italic>\n                    &amp;lt;0.001,\n                    <jats:italic>\n                      d\n                      <jats:sub>z<\/jats:sub>\n                    <\/jats:italic>\n                    =1.59]; FEV\n                    <jats:sub>1<\/jats:sub>\n                    from 2.4\u00b10.6 L to 2.9\u00b10.4 L [t(11)=\u22124.68,\n                    <jats:italic>p<\/jats:italic>\n                    =0.001,\n                    <jats:italic>\n                      d\n                      <jats:sub>z<\/jats:sub>\n                    <\/jats:italic>\n                    =1.35]; PEF from 3.9\u00b11.3 L\/s to 6.1\u00b10.5 L\/s [t(11)=\u22126.81,\n                    <jats:italic>p<\/jats:italic>\n                    &amp;lt;0.001,\n                    <jats:italic>\n                      d\n                      <jats:sub>z<\/jats:sub>\n                    <\/jats:italic>\n                    =1.97]; and the FEV\n                    <jats:sub>1<\/jats:sub>\n                    \/FVC ratio from 82.9\u00b12.9% to 89.6\u00b17.5% [t(11)=4.39,\n                    <jats:italic>p<\/jats:italic>\n                    =0.001,\n                    <jats:italic>\n                      d\n                      <jats:sub>z<\/jats:sub>\n                    <\/jats:italic>\n                    =1.27].\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion<\/jats:bold>\n                    : In women with nickel allergy, pulmonary function improves significantly after nickel avoidance. Pulmonary assessment and avoidance counseling should be integrated into the management of female nickel\u2011sensitized patients with respiratory symptoms.\n                  <\/jats:p>","DOI":"10.3897\/folmed.68.e177549","type":"journal-article","created":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T17:06:46Z","timestamp":1775149606000},"source":"Crossref","is-referenced-by-count":0,"title":["Reversible pulmonary function impairment in female patients with nickel sensitization: a cross-sectional observational study"],"prefix":"10.3897","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4515-8640","authenticated-orcid":true,"given":"Burim","family":"Neziri","sequence":"first","affiliation":[{"name":"Institute of Pathophysiology, UCCK, Prishtina, Kosovo"},{"name":"University of Prishtina, Prishtina, Kosovo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shqipe","family":"Devaja","sequence":"additional","affiliation":[{"name":"Institute of Pathophysiology, UCCK, Prishtina, Kosovo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samir","family":"Durmishi","sequence":"additional","affiliation":[{"name":"University of Prishtina, Prishtina, Kosovo"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2258","published-online":{"date-parts":[[2026,4,3]]},"reference":[{"key":"177549_B1"},{"key":"177549_B2","doi-asserted-by":"crossref","unstructured":"Genchi G, Carocci A, Lauria G, et al. 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