{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T15:01:10Z","timestamp":1781708470500,"version":"3.54.5"},"reference-count":34,"publisher":"Pensoft Publishers","issue":"3","license":[{"start":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T00:00:00Z","timestamp":1781654400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FM"],"abstract":"<jats:p>\n                    <jats:bold>Abstract<\/jats:bold>\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Introduction<\/jats:bold>\n                    : Total hip arthroplasty is one of the most successful modern surgical procedures, yet periprosthetic joint infection (PJI) remains a serious complication associated with disability and increased postoperative mortality.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Aim<\/jats:bold>\n                    : This study highlights the importance of identifying the causative microorganism and its antibiotic susceptibility profile for the successful application of a one-stage revision protocol in treating PJI.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Materials and methods<\/jats:bold>\n                    : Between October 2017 and July 2023, 33 patients underwent one-stage revision total hip arthroplasty. Preoperative joint aspiration and intraoperative periprosthetic tissue sampling were performed in all cases, with microbiological analysis conducted. The study group consisted of 15 men and 18 women, with a mean postoperative follow-up of 33 months (range 2\u201366 months).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results<\/jats:bold>\n                    : A pathogen was identified in 31 patients.\n                    <jats:italic>Staphylococcus epidermidis<\/jats:italic>\n                    was the most common microorganism, responsible for 44.1% of infections.\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    was found in 14.7% of cases.\n                    <jats:italic>Enterococcus faecalis<\/jats:italic>\n                    was isolated in three patients, and\n                    <jats:italic>Serratia marcescens<\/jats:italic>\n                    in two. No infection recurrence was recorded during follow-up. Complications included two postoperative dislocations, both managed with closed reduction, and one death due to pulmonary embolism. Functional outcomes improved, with the mean Harris Hip Score increasing from 54.3 preoperatively to 72.3 postoperatively.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion<\/jats:bold>\n                    : In this selected cohort, one-stage revision was associated with favorable short- to mid-term outcomes. These findings suggest that, when guided by precise microbiological diagnosis and multidisciplinary management, one-stage revision may be a viable option for carefully selected patients with periprosthetic hip infection.\n                  <\/jats:p>","DOI":"10.3897\/folmed.68.e182189","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T14:32:25Z","timestamp":1781706745000},"source":"Crossref","is-referenced-by-count":0,"title":["Clinical value of causative pathogen identification in one-stage revision for periprosthetic joint infection"],"prefix":"10.3897","volume":"68","author":[{"given":"Georgi","family":"Lukanov","sequence":"first","affiliation":[{"name":"Prof. B. Boychev University Hospital of Orthopedics, Medical University Sofia, Sofia, Bulgaria"},{"name":"Orthopedic Foundation for Research and Education, Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atanas","family":"Panev","sequence":"additional","affiliation":[{"name":"Prof. B. Boychev University Hospital of Orthopedics, Medical University Sofia, Sofia, Bulgaria"},{"name":"Orthopedic Foundation for Research and Education, Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lubomir","family":"Tzvetanov","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology, Queen Joanna University Hospital, Medical University of Sofia, Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevork","family":"Kaykchian","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology, Queen Joanna University Hospital, Medical University of Sofia, Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Gerchev","sequence":"additional","affiliation":[{"name":"Prof. B. Boychev University Hospital of Orthopedics, Medical University Sofia, Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Plamen","family":"Kinov","sequence":"additional","affiliation":[{"name":"Orthopedic Foundation for Research and Education, Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Slaveyko","family":"Djambazov","sequence":"additional","affiliation":[{"name":"Orthopedic Foundation for Research and Education, Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2258","published-online":{"date-parts":[[2026,6,17]]},"reference":[{"key":"182189_B1","doi-asserted-by":"crossref","unstructured":"Lamagni T. Epidemiology and burden of prosthetic joint infections. J Antimicrob Chemother 2014; 69(Suppl 1):i5\u201310.","DOI":"10.1093\/jac\/dku247"},{"key":"182189_B2","unstructured":"Tivchev P, Dimov V, Kinov P, et al. Periprosthetic infections. In: IX BOTA Congress: Collection of Reports. 2004. pp. 113\u20137."},{"key":"182189_B3","doi-asserted-by":"crossref","unstructured":"Bozic KJ, Ries MD. The impact of infection after total hip arthroplasty on hospital and surgeon resource utilization. J Bone Joint Surg Am 2005; 87(8):1746\u201351.","DOI":"10.2106\/00004623-200508000-00012"},{"key":"182189_B4","doi-asserted-by":"crossref","unstructured":"Kamath AF, Ong KL, Lau E, et al. Quantifying the burden of revision total joint arthroplasty for periprosthetic infection. J Arthroplasty 2015; 30(9):1492\u20137.","DOI":"10.1016\/j.arth.2015.03.035"},{"key":"182189_B5","unstructured":"Papalia R, Vespasiani-Gentilucci U, Longo UG, et al. Advances in management of periprosthetic joint infections: a historical prospective study. Eur Rev Med Pharmacol Sci 2019; 23(Suppl 2):129\u201338."},{"key":"182189_B6","unstructured":"European Centre for Disease Prevention and Control. Surveillance of surgical site infections in Europe 2008\u20132009. 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