{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T09:00:02Z","timestamp":1790240402575,"version":"4.1.0"},"reference-count":34,"publisher":"The Journal of Rheumatology","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Rheumatol"],"published-print":{"date-parts":[[2009,7]]},"abstract":"<jats:sec><jats:title>Objective.<\/jats:title><jats:p>To investigate the distribution of joint involvement in a cohort of patients with very recent onset arthritis and describe the disease characteristics in these patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>A very early arthritis clinic (NOR-VEAC) was established as a multicenter study. General practitioners were asked to refer patients presenting with at least 1 swollen joint of maximum 16 weeks\u2019 duration. Clinical and laboratory markers were examined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>We included 634 patients during the first 3 years, with mean (25th\u201375th percentile) arthritis duration of 30 (11\u201363) days. Monoarthritis was present in 243 (38.3%) patients, 216 (34.1%) had oligoarthritis, and 175 (27.6%) polyarthritis. Patients with polyarthritis were older, had longer duration of arthritis, and were more frequently anti-cyclic citrullinated peptide antibody and rheumatoid factor-positive. Patients in all 3 joint pattern groups (mono-\/oligo-\/polyarthritis) reported substantial effect on physical function, pain, and fatigue and had elevated levels of acute-phase reactants. Knee or ankle arthritis was most frequent in patients with mono- and oligoarthritis, whereas small joint involvement was most frequent in patients with polyarthritis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion.<\/jats:title><jats:p>Patients with recent-onset arthritis report a substantial influence on health status. Mono- and oligoarthritis are at least as frequent as polyarthritis. Polyarthritic patients more frequently exhibit features associated with a worse outcome.<\/jats:p><\/jats:sec>","DOI":"10.3899\/jrheum.081217","type":"journal-article","created":{"date-parts":[[2009,6,2]],"date-time":"2009-06-02T00:24:45Z","timestamp":1243902285000},"page":"1401-1406","source":"Crossref","is-referenced-by-count":29,"title":["Pattern of Joint Involvement and Other Disease Characteristics in 634 Patients with Arthritis of Less Than 16 Weeks\u2019 Duration"],"prefix":"10.3899","volume":"36","author":[{"given":"MARIA DAHL","family":"MJAAVATTEN","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ANNE JULSRUD","family":"HAUGEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KNUT","family":"HELGETVEIT","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HALVOR","family":"NYGAARD","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00d6RAN","family":"SIDENVALL","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"TILL","family":"UHLIG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"TORE KRISTIAN","family":"KVIEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2262","published-online":{"date-parts":[[2009,6,1]]},"reference":[{"key":"2018112909200063000_36.7.1401.1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.15.1.1"},{"key":"2018112909200063000_36.7.1401.2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780120205"},{"key":"2018112909200063000_36.7.1401.3","first-page":"123","article-title":"What is the natural history of rheumatoid arthritis?","volume":"19","author":"Pincus","year":"1993","journal-title":"Rheum Dis Clin North Am"},{"key":"2018112909200063000_36.7.1401.4","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keh199"},{"key":"2018112909200063000_36.7.1401.5","doi-asserted-by":"publisher","DOI":"10.1002\/art.22525"},{"key":"2018112909200063000_36.7.1401.6","doi-asserted-by":"publisher","DOI":"10.1136\/ard.61.10.911"},{"key":"2018112909200063000_36.7.1401.7","first-page":"2460","article-title":"Total incidence and distribution of inflammatory joint diseases in a defined population: results from the Kuopio 2000 arthritis survey","volume":"30","author":"Savolainen","year":"2003","journal-title":"J Rheumatol"},{"key":"2018112909200063000_36.7.1401.8","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-007-0801-0"},{"key":"2018112909200063000_36.7.1401.9","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2006.055657"},{"key":"2018112909200063000_36.7.1401.10","first-page":"1326","article-title":"Inflammatory polyarthritis in the community is not a benign disease: predicting functional disability one year after presentation","volume":"23","author":"Harrison","year":"1996","journal-title":"J Rheumatol"},{"key":"2018112909200063000_36.7.1401.11","doi-asserted-by":"publisher","DOI":"10.1136\/ard.61.8.700"},{"key":"2018112909200063000_36.7.1401.12","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kel237"},{"key":"2018112909200063000_36.7.1401.13","first-page":"115","article-title":"Reactive arthritis: incidence, triggering agents and clinical presentation","volume":"21","author":"Kvien","year":"1994","journal-title":"J Rheumatol"},{"key":"2018112909200063000_36.7.1401.14","doi-asserted-by":"publisher","DOI":"10.1002\/art.11269"},{"key":"2018112909200063000_36.7.1401.15","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1136\/ard.56.1.32","article-title":"Limited effect of sulphasalazine treatment in reactive arthritis. 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