{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T09:07:15Z","timestamp":1791104835689,"version":"4.1.0"},"reference-count":22,"publisher":"The Journal of Rheumatology","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Rheumatol"],"published-print":{"date-parts":[[2010,11]]},"abstract":"<jats:sec><jats:title>Objective.<\/jats:title><jats:p>Use of TA-US for diagnostic investigation of giant cell arteritis (GCA) has been proposed but remains a matter of debate because of the heterogeneous findings. We retrospectively evaluated operating characteristics of temporal artery ultrasonography (TA-US) in a single teaching hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>All subjects with suspected GCA had been seen between 2002 and 2008 and had undergone TA-US with continuous-wave Doppler (until 2004) or color duplex ultrasonography (after 2004), followed within 30 days by a temporal artery biopsy (TAB). TA-US findings were compared with TAB-proven GCA and clinically diagnosed GCA. Results are expressed as sensitivities, specificities, and positive (LR+) and negative likelihood ratios (LR\u2212) of stenoses, occlusions, and the halo sign; for the latter, only color duplex TA-US was considered.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>Seventy-seven patients fulfilled the selection criteria; 13 had TAB-proven and 19 had clinically defined GCA. Stenoses\/occlusions were seen on 45.5% of TA-US and the halo sign was seen only once (3.2%) in 31 duplex TA-US. Respective sensitivities, specificities, LR+, and LR\u2212 for GCA diagnosis (using TAB-proven\/clinically defined GCA as reference standards) were 69%\/53%, 59%\/57%, 1.7\/1.2, and 0.5\/0.8 for stenoses and\/or occlusions, and 17%\/10%, 100%\/100%, infinite\/infinite, and 0.8\/0.9 for the halo sign.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion.<\/jats:title><jats:p>The halo sign showed 100% specificity for GCA but only 10%\u201317% sensitivity. Stenoses\/occlusions were of low diagnostic value. These observations suggest that TA-US is neither an effective substitute for TAB nor a reliable screening test to decide which patients can be safely spared TAB.<\/jats:p><\/jats:sec>","DOI":"10.3899\/jrheum.100353","type":"journal-article","created":{"date-parts":[[2010,9,2]],"date-time":"2010-09-02T01:01:20Z","timestamp":1283389280000},"page":"2326-2330","source":"Crossref","is-referenced-by-count":42,"title":["Limited Value of Temporal Artery Ultrasonography Examinations for Diagnosis of Giant Cell Arteritis: Analysis of 77 Subjects"],"prefix":"10.3899","volume":"37","author":[{"given":"CARLA","family":"MALDINI","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CAROLINE","family":"D\u00c9PINAY-DHELLEMMES","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"THI T.S.","family":"TRA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MICHEL","family":"CHAUVEAU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YANNICK","family":"ALLANORE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LAURE","family":"GOSSEC","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GENEVI\u00c8VE","family":"TERRASSE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LO\u00cfC","family":"GUILLEVIN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JO\u00cbL","family":"COSTE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ALFRED","family":"MAHR","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2262","published-online":{"date-parts":[[2010,9,1]]},"reference":[{"key":"2018112909250898000_37.11.2326.1","first-page":"273","article-title":"Doppler examination in temporal arteritis. 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