{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T09:41:41Z","timestamp":1783762901091,"version":"3.55.0"},"reference-count":31,"publisher":"The Journal of Rheumatology","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Rheumatol"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:p>Autoimmune thyroid disease (AITD) is an inflammatory thyroiditis that in some cases is characterized by lymphocytic infiltration of the thyroid gland, also referred to as chronic lymphocytic thyroiditis or Hashimoto thyroiditis. Hashimoto thyroiditis is one of the commonest causes of hypothyroidism. Hypothyroidism has been associated with osteoarthritis (OA) and inflammatory forms of arthritis and with several well defined connective tissue diseases, which in turn can cause arthritis. The presence of arthritis in patients with AITD with normal thyroid function is now being increasingly recognized. There is also considerable evidence to suggest that AITD is highly associated with fibromyalgia syndrome. We review the current literature on the rheumatologic manifestations of AITD and describe the features in its presentation that set it apart from other forms of autoimmune arthritis.<\/jats:p>","DOI":"10.3899\/jrheum.120022","type":"journal-article","created":{"date-parts":[[2012,4,15]],"date-time":"2012-04-15T20:13:42Z","timestamp":1334520822000},"page":"1125-1129","source":"Crossref","is-referenced-by-count":44,"title":["Rheumatic Manifestations of Autoimmune Thyroid Disease: The Other Autoimmune Disease"],"prefix":"10.3899","volume":"39","author":[{"given":"CLEMENT E.","family":"TAGOE","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ANNA","family":"ZEZON","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SAAKSHI","family":"KHATTRI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2262","published-online":{"date-parts":[[2012,4,15]]},"reference":[{"key":"2018112909275516000_39.6.1125.1","first-page":"1769","article-title":"Thyroiditis","volume":"73","author":"Bindra","year":"2006","journal-title":"Am Fam Physician"},{"key":"2018112909275516000_39.6.1125.2","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e32832cf824"},{"key":"2018112909275516000_39.6.1125.3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199607113350206"},{"key":"2018112909275516000_39.6.1125.4","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1480001"},{"key":"2018112909275516000_39.6.1125.5","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1089\/thy.2000.10.251","article-title":"The value of ultrasonography in predicting autoimmune thyroid disease","volume":"10","author":"Pedersen","year":"2000","journal-title":"Thyroid"},{"key":"2018112909275516000_39.6.1125.6","doi-asserted-by":"publisher","DOI":"10.1089\/105072503322021151"},{"key":"2018112909275516000_39.6.1125.7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2009.04809.x"},{"key":"2018112909275516000_39.6.1125.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2009.06.030"},{"key":"2018112909275516000_39.6.1125.9","doi-asserted-by":"publisher","DOI":"10.1080\/17402520400008897"},{"key":"2018112909275516000_39.6.1125.10","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1056\/NEJM196302072680601","article-title":"The connective-tissue diseases and symptoms associated with Hashimoto\u2019s thyroiditis","volume":"268","author":"Becker","year":"1963","journal-title":"N Engl J Med"},{"key":"2018112909275516000_39.6.1125.11","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-005-1165-y"},{"key":"2018112909275516000_39.6.1125.12","doi-asserted-by":"publisher","DOI":"10.1097\/01.ede.0000193605.93416.df"},{"key":"2018112909275516000_39.6.1125.13","first-page":"323","article-title":"Hashimoto\u2019s thyroiditis presenting as bilateral knee arthropathy","volume":"95","author":"Gillan","year":"2002","journal-title":"J Okla State Med Assoc"},{"key":"2018112909275516000_39.6.1125.14","first-page":"55","article-title":"Arthropathies and thyroid diseases","volume":"29","author":"Longato","year":"2004","journal-title":"Minerva Endocrinol"},{"key":"2018112909275516000_39.6.1125.15","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-007-0636-8"},{"key":"2018112909275516000_39.6.1125.16","doi-asserted-by":"crossref","unstructured":"Cho JH Gregersen PK . Genomics and the multifactorial nature of human autoimmune disease. N Engl J Med;365:1612\u201323.","DOI":"10.1056\/NEJMra1100030"},{"key":"2018112909275516000_39.6.1125.17","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1214415"},{"key":"2018112909275516000_39.6.1125.18","doi-asserted-by":"publisher","DOI":"10.1186\/1743-422X-6-5"},{"key":"2018112909275516000_39.6.1125.19","doi-asserted-by":"publisher","DOI":"10.1177\/014107689108400216"},{"key":"2018112909275516000_39.6.1125.20","doi-asserted-by":"publisher","DOI":"10.1177\/014107689308600304"},{"key":"2018112909275516000_39.6.1125.21","doi-asserted-by":"publisher","DOI":"10.1016\/0049-0172(79)90002-7"},{"key":"2018112909275516000_39.6.1125.22","doi-asserted-by":"publisher","DOI":"10.1136\/ard.43.4.594"},{"key":"2018112909275516000_39.6.1125.23","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1053\/sarh.2002.33722","article-title":"Clinical manifestations and outcome of polyarthralgia associated with chronic lymphocytic thyroiditis","volume":"32","author":"Punzi","year":"2002","journal-title":"Semin Arthritis Rheum"},{"key":"2018112909275516000_39.6.1125.24","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1007\/BF03346432","article-title":"Prevalence of interrelated autoantibodies in thyroid diseases and autoimmune disorders","volume":"31","author":"Nakamura","year":"2008","journal-title":"J Endocrinol Invest"},{"key":"2018112909275516000_39.6.1125.25","doi-asserted-by":"publisher","DOI":"10.1080\/08916930701620100"},{"key":"2018112909275516000_39.6.1125.26","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/S0140-6736(79)90238-1","article-title":"Antithyroid-antibody activity in the synovial fluid of patients with various arthritides","volume":"2","author":"Blake","year":"1979","journal-title":"Lancet"},{"key":"2018112909275516000_39.6.1125.27","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s10067-006-0237-y","article-title":"The frequency of thyroid antibodies in fibromyalgia patients and their relationship with symptoms","volume":"26","author":"Pamuk","year":"2007","journal-title":"Clin Rheumatol"},{"key":"2018112909275516000_39.6.1125.28","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/s00296-010-1620-1","article-title":"Thyroid autoimmunity may represent a predisposition for the development of fibromyalgia","volume":"32","author":"Bazzichi","year":"2010","journal-title":"Rheumatol Int"},{"key":"2018112909275516000_39.6.1125.29","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-2179"},{"key":"2018112909275516000_39.6.1125.30","doi-asserted-by":"publisher","DOI":"10.1089\/105072502753452011"},{"key":"2018112909275516000_39.6.1125.31","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2006.12.056"}],"container-title":["The Journal of Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.3899\/jrheum.120022","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,11,29]],"date-time":"2018-11-29T13:14:17Z","timestamp":1543497257000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jrheum.org\/lookup\/doi\/10.3899\/jrheum.120022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4,15]]},"references-count":31,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2012,6,1]]},"published-print":{"date-parts":[[2012,6]]}},"alternative-id":["10.3899\/jrheum.120022"],"URL":"https:\/\/doi.org\/10.3899\/jrheum.120022","relation":{},"ISSN":["0315-162X","1499-2752"],"issn-type":[{"value":"0315-162X","type":"print"},{"value":"1499-2752","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,15]]}}}