{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T19:02:58Z","timestamp":1773514978538,"version":"3.50.1"},"reference-count":25,"publisher":"The Journal of Rheumatology","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Rheumatol"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:sec><jats:title>Objective.<\/jats:title><jats:p>Temporomandibular joint (TMJ) inflammation in patients with juvenile idiopathic arthritis (JIA) may lead to mandibular growth disturbances and interfere with optimal joint and muscle function. Orofacial symptoms are common clinical findings in relation to TMJ arthritis in adolescence. Knowledge about their clinical manifestation is important for TMJ arthritis diagnosis, treatment choice, and outcome evaluation. The aim of our prospective observational study was to evaluate and describe the frequency, the main complaints, and the localization of TMJ arthritis-related orofacial symptoms. The smallest detectable differences (SDD) for minimal, average, and maximal pain were estimated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>Thirty-three patients with JIA and arthritis-related orofacial symptoms in relation to 55 affected TMJ were included in our questionnaire study (mean age 14.11 yrs). Calculation of the SDD was based on a duplicate assessment 45 min after the first questionnaire was completed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>The majority of the patients had common orofacial symptoms during mastication and maximal mouth opening procedures. Persistent orofacial symptoms were rare. The TMJ area in combination with the masseter muscle region was the orofacial region where symptoms were most common. The SDD for minimal, average, and maximal pain were between 10 and 14 mm on a visual analog scale.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion.<\/jats:title><jats:p>Our study offers new knowledge about TMJ arthritis-related orofacial symptoms that may aid diagnosis and clinical decision-making. We suggest that TMJ arthritis-related orofacial symptoms could be understood as products of the primary TMJ inflammation in combination with secondary myogenic and functional issues.<\/jats:p><\/jats:sec>","DOI":"10.3899\/jrheum.120437","type":"journal-article","created":{"date-parts":[[2012,10,2]],"date-time":"2012-10-02T05:11:51Z","timestamp":1349154711000},"page":"2352-2358","source":"Crossref","is-referenced-by-count":30,"title":["Orofacial Symptoms Related to Temporomandibular Joint Arthritis in Juvenile Idiopathic Arthritis: Smallest Detectable Difference in Self-reported Pain Intensity"],"prefix":"10.3899","volume":"39","author":[{"given":"PETER","family":"STOUSTRUP","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KASPER D.","family":"KRISTENSEN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CARLALBERTA","family":"VERNA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ANNELISE","family":"K\u00dcSELER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"TROELS","family":"HERLIN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"THOMAS K.","family":"PEDERSEN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2262","published-online":{"date-parts":[[2012,10,1]]},"reference":[{"key":"2018112909283501000_39.12.2352.1","first-page":"390","article-title":"International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001","volume":"31","author":"Petty","year":"2004","journal-title":"J Rheumatol"},{"key":"2018112909283501000_39.12.2352.2","doi-asserted-by":"publisher","DOI":"10.1097\/01.bor.0000240360.24465.4c"},{"key":"2018112909283501000_39.12.2352.3","first-page":"329","article-title":"An investigation of the dental occlusion in children with juvenile rheumatoid arthritis","volume":"44","author":"Barriga","year":"1974","journal-title":"Angle Orthod"},{"key":"2018112909283501000_39.12.2352.4","first-page":"1406","article-title":"Contrast enhanced magnetic resonance imaging as a method to diagnose early inflammatory changes in the temporomandibular joint in children with juvenile chronic arthritis","volume":"25","author":"Kuseler","year":"1998","journal-title":"J Rheumatol"},{"key":"2018112909283501000_39.12.2352.5","first-page":"2109","article-title":"Resorption of the temporomandibular condylar bone according to subtypes of juvenile chronic arthritis","volume":"28","author":"Pedersen","year":"2001","journal-title":"J Rheumatol"},{"key":"2018112909283501000_39.12.2352.6","first-page":"1418","article-title":"Temporomandibular involvement in juvenile idiopathic arthritis","volume":"31","author":"Twilt","year":"2004","journal-title":"J Rheumatol"},{"key":"2018112909283501000_39.12.2352.7","doi-asserted-by":"publisher","DOI":"10.1002\/art.23401"},{"key":"2018112909283501000_39.12.2352.8","doi-asserted-by":"publisher","DOI":"10.1067\/moe.2001.115467"},{"key":"2018112909283501000_39.12.2352.9","first-page":"1668","article-title":"A prospective study of magnetic resonance and radiographic imaging in relation to symptoms and clinical findings of the temporomandibular joint in children with juvenile idiopathic arthritis","volume":"35","author":"Pedersen","year":"2008","journal-title":"J Rheumatol"},{"key":"2018112909283501000_39.12.2352.10","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kep068"},{"key":"2018112909283501000_39.12.2352.11","first-page":"120","article-title":"Juvenile arthritis and development of symptoms of temporomandibular disorders: A 15\u2013year prospective cohort study","volume":"21","author":"Engstrom","year":"2007","journal-title":"J Orofac Pain"},{"key":"2018112909283501000_39.12.2352.12","first-page":"71","article-title":"Craniomandibular function in juvenile chronic arthritis. 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