{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:56:14Z","timestamp":1772160974522,"version":"3.50.1"},"reference-count":56,"publisher":"The Journal of Rheumatology","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Rheumatol"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:sec><jats:title>Objective.<\/jats:title><jats:p>To explore 5 possible criteria for remission in rheumatoid arthritis (RA) based on a patient self-report index, the Routine Assessment of Patient Index Data (RAPID3), with a careful joint examination and possible physician global estimate (DOCGL), but without a formal joint count or laboratory test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>The ESPOIR early RA cohort of 813 French patients recruited in 2002\u20132005 was analyzed to identify patients in remission 6 months after enrollment, according to 2 American College of Rheumatology\/European League Against Rheumatism (ACR\/EULAR) criteria: Boolean \u2264 1 for total tender joint count-28, swollen joint count-28, C-reactive protein, and patient global estimate (PATGL), and Simplified Disease Activity Index (SDAI) \u2264 3.3. Agreement with 7 other remission criteria was analyzed \u2014 Disease Activity Score-28 (DAS28) \u2264 2.6, Clinical Disease Activity Index (CDAI) \u2264 2.8, and 5 candidate criteria based on RAPID3, joint examination, and DOCGL: \u201cRAPID3R\u201d (RAPID3 \u2264 3.0); \u201cRAPID3R+SJ1\u201d (RAPID3 \u2264 3.0, \u2264 1 swollen joint); \u201cRAPID3R+SJ1+D1\u201d (RAPID3 \u2264 3.0, \u2264 1 swollen joint, DOCGL \u2264 1); \u201cRAPID3R+SJ0\u201d (RAPID3 \u2264 3.0, 0 swollen joints); and \u201cRAPID3R+SJ0+D1\u201d (RAPID3 \u2264 3.0, 0 swollen joints, DOCGL \u2264 1), according to kappa statistics, sensitivity, and specificity. Residual global, articular, and questionnaire abnormalities according to each criteria set were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>Among 813 ESPOIR patients, 720 had complete data to compare all 9 possible criteria. Substantial agreement with the Boolean criteria was seen for SDAI, CDAI, RAPID3R+SJ1, RAPID3R+SJ1+D1, RAPID3R+SJ0, and RAPID3R+SJ0+D1 (92.2%\u201394.7%, kappa 0.67\u20130.79), versus only moderate agreement for DAS28 or RAPID3R (79.9%\u201385.8%, kappa 0.46\u20130.55).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion.<\/jats:title><jats:p>Remission according to CDAI and RAPID3R+SJ1, but not DAS28 or RAPID3R, is similar to that of the ACR\/EULAR criteria. RAPID3 scores require a complementary careful joint examination for clinical decisions, do not preclude formal joint counts or other indices, and may be useful in busy clinical settings.<\/jats:p><\/jats:sec>","DOI":"10.3899\/jrheum.121059","type":"journal-article","created":{"date-parts":[[2013,2,2]],"date-time":"2013-02-02T03:34:20Z","timestamp":1359776060000},"page":"386-393","source":"Crossref","is-referenced-by-count":26,"title":["Can Remission in Rheumatoid Arthritis Be Assessed Without Laboratory Tests or a Formal Joint Count? Possible Remission Criteria Based on a Self-report RAPID3 Score and Careful Joint Examination in the ESPOIR 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