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To test criterion validity, we compared the baseline FI to that at last recorded visit and to mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>The mean CSRG-FI was 0.33 with a sub-maximal limit of 0.67. In patients with diffuse disease, the mean was 0.38(SD 0.14); in patients with limited disease, the mean was 0.31(SD 0.13). The CSRG-FI was weakly (but significantly) correlated with the Rodnan Skin Score (r = 0.28 in people with diffuse disease; 0.18 with limited) and moderately with the Physician Assessment of Damage (r = 0.51 for both limited and diffuse). The risk of death increased with higher FI scores and with higher physician ratings of damage. The area under the receiver operating characteristic curve for the baseline FI in relation to death was 0.75, higher than for other measures (range: 0.57\u20130.67).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion.<\/jats:title><jats:p>The FI quantifies overall health status in people with scleroderma and predicts mortality. Whether the FI might help with decisions about who might best be served by more aggressive treatment, such as bone marrow transplantation, needs to be evaluated.<\/jats:p><\/jats:sec>","DOI":"10.3899\/jrheum.130182","type":"journal-article","created":{"date-parts":[[2014,3,1]],"date-time":"2014-03-01T20:34:26Z","timestamp":1393706066000},"page":"698-705","source":"Crossref","is-referenced-by-count":58,"title":["Frailty Index to Measure Health Status in People with Systemic Sclerosis"],"prefix":"10.3899","volume":"41","author":[{"given":"Michael R.","family":"Rockwood","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen","family":"MacDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyn","family":"Sutton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth","family":"Rockwood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Canadian Scleroderma Research Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murray","family":"Baron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2262","published-online":{"date-parts":[[2014,3,1]]},"reference":[{"key":"2018112909324003000_41.4.698.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2010.10.007"},{"key":"2018112909324003000_41.4.698.2","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2010.0275"},{"key":"2018112909324003000_41.4.698.3","doi-asserted-by":"publisher","DOI":"10.1007\/s10522-010-9287-2"},{"key":"2018112909324003000_41.4.698.4","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afr182"},{"key":"2018112909324003000_41.4.698.5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2011.03597.x"},{"key":"2018112909324003000_41.4.698.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2010.09.001"},{"key":"2018112909324003000_41.4.698.7","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/56.3.M146"},{"key":"2018112909324003000_41.4.698.8","doi-asserted-by":"publisher","DOI":"10.1100\/tsw.2001.58"},{"key":"2018112909324003000_41.4.698.9","unstructured":"Seibold JR . 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