{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T17:31:48Z","timestamp":1787160708339,"version":"build-2736575974"},"reference-count":30,"publisher":"The Journal of Rheumatology","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Rheumatol"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective.<\/jats:title>\n                    <jats:p>Discrimination of diffuse idiopathic skeletal hyperostosis (DISH) and ankylosing spondylitis (AS) can be challenging. Usefulness of whole-body magnetic resonance imaging (WB-MRI) in diagnosing spondyloarthritis has been recently proved. We assessed the value of clinical variables alone and in combination with WB-MRI to distinguish between DISH and AS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods.<\/jats:title>\n                    <jats:p>Diagnostic case-control study: 33 patients with AS and 15 patients with DISH were included. All patients underwent 1.5 Tesla WB-MRI scanning. MR scans were read by a blinded radiologist using the Canadian-Danish Working Group\u2019s recommendation. Imaging and clinical variables were identified using the bootstrap. The most important variables from MR and clinical history were assessed in a multivariate fashion resulting in 3 diagnostic models (MRI, clinical, and combined). The discriminative capacity was quantified using the area under the receiver-operating characteristic (ROC) curve. The strength of diagnostic variables was quantified with OR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results.<\/jats:title>\n                    <jats:p>Forty-eight patients provided 1545 positive findings (193 DISH\/1352 AS). The final MR model contained upper anterior corner fat infiltration (32 DISH\/181 AS), ankylosis on the vertebral endplate (4 DISH\/60 AS), facet joint ankylosis (4 DISH\/49 AS), sacroiliac joint edema (11 DISH\/91 AS), sacroiliac joint fat infiltration (2 DISH\/114 AS), sacroiliac joint ankylosis (2 DISH\/119 AS); area under the ROC curve was 0.71, 95% CI 0.64\u20130.78. The final clinical model contained patient\u2019s age and body mass index (area under the ROC curve 0.90, 95% CI 0.89\u20130.91). The full diagnostic model containing clinical and MR information had an area under the ROC curve of 0.93 (95% CI 0.92\u20130.95).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion.<\/jats:title>\n                    <jats:p>WB-MRI features can contribute to the correct diagnosis after a thorough conventional workup of patients with DISH and AS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3899\/jrheum.150162","type":"journal-article","created":{"date-parts":[[2015,12,15]],"date-time":"2015-12-15T21:39:53Z","timestamp":1450215593000},"page":"335-342","source":"Crossref","is-referenced-by-count":38,"title":["Whole Body Magnetic Resonance Imaging Features in Diffuse Idiopathic Skeletal Hyperostosis in Conjunction with Clinical Variables to Whole Body MRI and Clinical Variables in Ankylosing Spondylitis"],"prefix":"10.3899","volume":"43","author":[{"given":"Bettina G.","family":"Weiss","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas M.","family":"Bachmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian W.A.","family":"Pfirrmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudolf O.","family":"Kissling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronika","family":"Zubler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2262","published-online":{"date-parts":[[2015,12,15]]},"reference":[{"key":"2018112909351957000_43.2.335.1","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-009-0046-9"},{"key":"2018112909351957000_43.2.335.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2012.10.005"},{"key":"2018112909351957000_43.2.335.3","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2009.108233"},{"key":"2018112909351957000_43.2.335.4","doi-asserted-by":"publisher","DOI":"10.1148\/119.3.559"},{"key":"2018112909351957000_43.2.335.5","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kem227"},{"key":"2018112909351957000_43.2.335.6","doi-asserted-by":"publisher","DOI":"10.1007\/BF02041404"},{"key":"2018112909351957000_43.2.335.7","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.121433"},{"key":"2018112909351957000_43.2.335.8","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-138-1-200301070-00010"},{"key":"2018112909351957000_43.2.335.9","doi-asserted-by":"publisher","DOI":"10.1016\/S0950-3579(05)80297-3"},{"key":"2018112909351957000_43.2.335.10","doi-asserted-by":"publisher","DOI":"10.1002\/art.24507"},{"key":"2018112909351957000_43.2.335.11","doi-asserted-by":"publisher","DOI":"10.1002\/art.27571"},{"key":"2018112909351957000_43.2.335.12","doi-asserted-by":"publisher","DOI":"10.1002\/art.24542"},{"key":"2018112909351957000_43.2.335.13","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.130568"},{"key":"2018112909351957000_43.2.335.14","doi-asserted-by":"publisher","DOI":"10.1002\/acr.21893"},{"key":"2018112909351957000_43.2.335.15","doi-asserted-by":"publisher","DOI":"10.1002\/art.38140"},{"key":"2018112909351957000_43.2.335.16","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.090620"},{"key":"2018112909351957000_43.2.335.17","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-198712000-00017"},{"key":"2018112909351957000_43.2.335.18","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-203887"},{"key":"2018112909351957000_43.2.335.19","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20007"},{"key":"2018112909351957000_43.2.335.20","doi-asserted-by":"publisher","DOI":"10.1002\/acr.21742"},{"key":"2018112909351957000_43.2.335.21","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199703000-00003"},{"key":"2018112909351957000_43.2.335.22","doi-asserted-by":"publisher","DOI":"10.1002\/art.39001"},{"key":"2018112909351957000_43.2.335.23","doi-asserted-by":"publisher","DOI":"10.1002\/art.21337"},{"key":"2018112909351957000_43.2.335.24","doi-asserted-by":"publisher","DOI":"10.1002\/art.21445"},{"key":"2018112909351957000_43.2.335.25","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.094839"},{"key":"2018112909351957000_43.2.335.26","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2008.01.010"},{"key":"2018112909351957000_43.2.335.27","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2013.165"},{"key":"2018112909351957000_43.2.335.28","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.130647"},{"key":"2018112909351957000_43.2.335.29","doi-asserted-by":"publisher","DOI":"10.1002\/art.33447"},{"key":"2018112909351957000_43.2.335.30","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.172.3.2788894"}],"container-title":["The 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