{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,25]],"date-time":"2024-07-25T09:54:54Z","timestamp":1721901294720},"reference-count":17,"publisher":"The Journal of Rheumatology","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Rheumatol"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:sec><jats:title>Objective.<\/jats:title><jats:p>Neck pain is common in rheumatoid arthritis (RA) and ankylosing spondylitis (AS). We investigated the correlation of bone marrow edema (BME) on magnetic resonance imaging (MRI) in RA and AS and its association with clinical complaints of neck pain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>Cervical spine short-tau inversion recovery-MRI and T1w-MRI of 34 patients with RA and 6 patients with AS complaining about neck pain were obtained. Clinical and laboratory data were available. BME was scored by 2 blinded readers using a modification of a published score, including various cervical sites. Degenerative changes were also quantified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>Patients were predominantly women (82.5%), and mean \u00b1 SD age was 57.5 \u00b1 11.8 years, C-reactive protein (CRP) was 0.8 \u00b1 1.3 mg\/dl, and pain score was 46.0 \u00b1 17.5. BME was detected in 24\/40 patients (60%) involving the atlantoaxial region (21%), vertebral bodies (75%), facet joints (29%), and spinous processes (46%). Degenerative changes were identified in 21\/40 patients (52.5%), 13 (62%) of whom also had BME in vertebral bodies. No differences were found between patients with versus without cervical BME for clinical assessments: numeric rating scale pain (median \u00b1 interquartile range) 5.5 \u00b1 3.0 vs 6.0 \u00b1 4.0 (p = 0.69), Funktionsfragebogen Hannover 68.2 \u00b1 41.0 vs 42.0 \u00b1 55.5 (p = 0.19), Northwick pain score 44.4 \u00b1 21.8 vs 47.2 \u00b1 27.0 (p = 0.83), or CRP 0.40 \u00b1 0.80 vs 0.60 \u00b1 0.66 (p = 0.94). For patients with degenerative changes, symptom duration was longer than for patients without (10 \u00b1 12.5 vs 5.0 \u00b1 18.0 yrs, p = 0.73).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion.<\/jats:title><jats:p>In this small study of patients with RA and AS complaining about neck pain, BME was found in many different cervical sites, including the facet joints and the spinous processes. However, the occurrence and severity of BME did not correlate with the severity of neck pain.<\/jats:p><\/jats:sec>","DOI":"10.3899\/jrheum.150553","type":"journal-article","created":{"date-parts":[[2016,10,16]],"date-time":"2016-10-16T00:48:28Z","timestamp":1476578908000},"page":"2131-2135","source":"Crossref","is-referenced-by-count":6,"title":["Quantification of Bone Marrow Edema by Magnetic Resonance Imaging Only Marginally Reflects Clinical Neck Pain Evaluation in Rheumatoid Arthritis and Ankylosing Spondylitis"],"prefix":"10.3899","volume":"43","author":[{"given":"Xenofon","family":"Baraliakos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Heldmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johanna","family":"Callhoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravi","family":"Suppiah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fiona Marion","family":"McQueen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dietmar","family":"Krause","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Klink","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elmar","family":"Schmitz-Bortz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manfred","family":"Igelmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ludwig","family":"Kalthoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uta","family":"Kiltz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Schmuedderich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juergen","family":"Braun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2262","published-online":{"date-parts":[[2016,10,15]]},"reference":[{"key":"2018112909362986000_43.12.2131.1","unstructured":"Heldmann F Baraliakos X Kiltz U Krause D Klink C Schmitz-Bortz E The significance of neck pain in a population of patients with rheumatoid arthritis and ankylosing spondylitis-first results of the Cassandra trial [abstract]. 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