{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:56:41Z","timestamp":1787504201143,"version":"build-2736575974"},"reference-count":19,"publisher":"The Journal of Rheumatology","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Rheumatol"],"published-print":{"date-parts":[[2017,4]]},"abstract":"\n Objective.<\/jats:title>\n Because there are no epidemiologic data regarding the frequency of ankle osteoarthritis (OA) in a general population, we sought to analyze this disabling condition in a large, well-characterized, community-based cohort of older individuals.<\/jats:p>\n <\/jats:sec>\n \n Methods.<\/jats:title>\n Cross-sectional data, including ankle radiographs, were from the most recent data collection (2013\u20132015) of the Johnston County OA Project. Radiographic ankle OA (rAOA) was defined as a Kellgren-Lawrence arthritis grading scale of \u2265 2 on weight-bearing lateral and mortise radiographs. The presence of pain, aching, or stiffness in the ankles as well as history of ankle injury (limiting ability to walk for at least 2 days) were assessed. Chi-square statistics (categorical variables) and Student t tests (continuous variables) were used to compare all participant characteristics by rAOA status. Joint-based logistic regression models with generalized estimating equations were used to examine associations of rAOA and covariates of interest [age, body mass index (BMI), sex, race, ankle symptoms, and injury history].<\/jats:p>\n <\/jats:sec>\n \n Results.<\/jats:title>\n \n Of 864 participants with available data, 68% were women, 34% were African American, with a mean age of 72 years and BMI of 31 kg\/m\n 2<\/jats:sup>\n . Nearly 7% of this sample had rAOA. Increasing age, high BMI, history of ankle injury, and presence of ankle symptoms were all independently associated with greater odds of having rAOA; no significant differences were seen by sex or race.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion.<\/jats:title>\n The frequency of rAOA was higher than estimates generally quoted in the literature. While injury was an important contributor, other factors such as age, BMI, and symptoms were also significantly associated with rAOA.<\/jats:p>\n <\/jats:sec>","DOI":"10.3899\/jrheum.161076","type":"journal-article","created":{"date-parts":[[2017,2,15]],"date-time":"2017-02-15T20:25:25Z","timestamp":1487190325000},"page":"499-504","source":"Crossref","is-referenced-by-count":29,"title":["A Cross-sectional Analysis of Radiographic Ankle Osteoarthritis Frequency and Associated Factors: The Johnston County Osteoarthritis Project"],"prefix":"10.3899","volume":"44","author":[{"given":"Shahmeer","family":"Lateef","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvonne M.","family":"Golightly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan B.","family":"Renner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanne M.","family":"Jordan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda E.","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2262","published-online":{"date-parts":[[2017,2,15]]},"reference":[{"key":"2018112909371156000_44.4.499.1","first-page":"421","article-title":"Prevalence and most common causes of disability among adults\u2014United States, 2005","volume":"58","year":"2009","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2018112909371156000_44.4.499.2","unstructured":"Peyron JG . In: Moskowitz RW Howell DS Goldberg VM Mankin HJ , editors. Osteoarthritis: diagnosis and treatment, 1st ed. Philadelphia: Saunders; 1984:9\u201327."},{"key":"2018112909371156000_44.4.499.3","unstructured":"Funk FJ . Osteoarthritis of the foot and ankle. In: AAOS , editor. Symposium on osteoarthritis. St. Louis: The C.V. Mosby Company; 1976:287\u2013301."},{"key":"2018112909371156000_44.4.499.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.fcl.2013.06.001"},{"key":"2018112909371156000_44.4.499.5","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.F.01299"},{"key":"2018112909371156000_44.4.499.6","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-008-0543-6"},{"key":"2018112909371156000_44.4.499.7","doi-asserted-by":"publisher","DOI":"10.1177\/107110070502600707"},{"key":"2018112909371156000_44.4.499.8","doi-asserted-by":"crossref","first-page":"923","DOI":"10.2106\/00004623-200305000-00026","article-title":"Ankle arthritis","volume":"85-A","author":"Thomas","year":"2003","journal-title":"J Bone Joint Surg Am"},{"key":"2018112909371156000_44.4.499.9","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.F.00295"},{"key":"2018112909371156000_44.4.499.10","doi-asserted-by":"publisher","DOI":"10.1097\/BOT.0b013e31818915d9"},{"key":"2018112909371156000_44.4.499.11","doi-asserted-by":"publisher","DOI":"10.1097\/01.bot.0000246468.80635.ef"},{"key":"2018112909371156000_44.4.499.12","first-page":"w13583","article-title":"Biomechanics and pathomechanisms of osteoarthritis","volume":"142","author":"Egloff","year":"2012","journal-title":"Swiss Med Wkly"},{"key":"2018112909371156000_44.4.499.13","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1016\/j.joca.2013.07.008","article-title":"High prevalence of contralateral ankle abnormalities in association with knee osteoarthritis and malalignment","volume":"21","author":"Kraus","year":"2013","journal-title":"Osteoarthritis Cartilage"},{"key":"2018112909371156000_44.4.499.14","doi-asserted-by":"publisher","DOI":"10.1053\/j.jfas.2014.12.042"},{"key":"2018112909371156000_44.4.499.15","first-page":"172","article-title":"Prevalence of knee symptoms and radiographic and symptomatic knee osteoarthritis in African Americans and Caucasians: the Johnston County Osteoarthritis Project","volume":"34","author":"Jordan","year":"2007","journal-title":"J Rheumatol"},{"key":"2018112909371156000_44.4.499.16","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2015.08.008"},{"key":"2018112909371156000_44.4.499.17","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-8-48"},{"key":"2018112909371156000_44.4.499.18","doi-asserted-by":"publisher","DOI":"10.3113\/FAI.2007.0996"},{"key":"2018112909371156000_44.4.499.19","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/s13075-015-0589-2","article-title":"Racial disparities in total ankle arthroplasty utilization and outcomes","volume":"17","author":"Singh","year":"2015","journal-title":"Arthritis Res Ther"}],"container-title":["The Journal of Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.3899\/jrheum.161076","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,11,29]],"date-time":"2018-11-29T14:16:29Z","timestamp":1543500989000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jrheum.org\/lookup\/doi\/10.3899\/jrheum.161076"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,15]]},"references-count":19,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2017,4,1]]},"published-print":{"date-parts":[[2017,4]]}},"alternative-id":["10.3899\/jrheum.161076"],"URL":"https:\/\/doi.org\/10.3899\/jrheum.161076","relation":{},"ISSN":["0315-162X","1499-2752"],"issn-type":[{"value":"0315-162X","type":"print"},{"value":"1499-2752","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,15]]}}}