{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T19:57:06Z","timestamp":1780084626293,"version":"3.54.0"},"reference-count":20,"publisher":"The Journal of Rheumatology","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Rheumatol"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:sec><jats:title>Objective.<\/jats:title><jats:p>To assess in-hospital gout flares in patients with gout.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>Hospitalizations were evaluated for gout flares in a cohort of Olmsted County, Minnesota, residents with incident gout in 1989\u20131992 or 2009\u20132010.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>There were 429 patients followed up to 5 years. Of these, 169 patients experienced 454 hospitalizations. Hospitalization rates increased without reaching statistical significance from 1989\u20131992 to 2009\u20132010 [rate ratio (RR) 1.19, 95% CI 0.98\u20131.45]. The gout flare rate increased significantly during hospitalization (RR 10.2, 95% CI 6.8\u201314.5). In-hospital gout flare increased the average hospital stay by 1.8 days (p &lt; 0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion.<\/jats:title><jats:p>Hospitalization increased the risk of gout flares 10-fold. In-hospital gout flares were associated with longer hospitalization.<\/jats:p><\/jats:sec>","DOI":"10.3899\/jrheum.171320","type":"journal-article","created":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T11:29:46Z","timestamp":1530444586000},"page":"1188-1191","source":"Crossref","is-referenced-by-count":22,"title":["Hospitalization Increases the Risk of Acute Arthritic Flares in Gout: A Population-based Study over 2 Decades"],"prefix":"10.3899","volume":"45","author":[{"given":"Nour","family":"Zleik","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohanad M.","family":"Elfishawi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoran","family":"Kvrgic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Clement J.","family":"Michet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia S.","family":"Crowson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric L.","family":"Matteson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Bongartz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2262","published-online":{"date-parts":[[2018,7,1]]},"reference":[{"key":"2018112909385365000_45.8.1188.1","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2015.91"},{"key":"2018112909385365000_45.8.1188.2","doi-asserted-by":"publisher","DOI":"10.1002\/art.30520"},{"key":"2018112909385365000_45.8.1188.3","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.151419"},{"key":"2018112909385365000_45.8.1188.4","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.151432"},{"key":"2018112909385365000_45.8.1188.5","doi-asserted-by":"publisher","DOI":"10.1007\/s40273-015-0288-5"},{"key":"2018112909385365000_45.8.1188.6","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2007.081604"},{"key":"2018112909385365000_45.8.1188.7","doi-asserted-by":"crossref","first-page":"2345","DOI":"10.1001\/jama.2016.3517","article-title":"Trends in gout and rheumatoid arthritis hospitalizations in the United States, 1993\u20132011","volume":"315","author":"Lim","year":"2016","journal-title":"JAMA"},{"key":"2018112909385365000_45.8.1188.8","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1111\/j.1445-5994.2012.02747.x","article-title":"Healthcare burden of in-hospital gout","volume":"42","author":"Lee","year":"2012","journal-title":"Intern Med J"},{"key":"2018112909385365000_45.8.1188.9","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwq482"},{"key":"2018112909385365000_45.8.1188.10","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780200320"},{"key":"2018112909385365000_45.8.1188.11","unstructured":"Kellgren JH Jeffrey MR Ball J . 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