{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T18:53:44Z","timestamp":1773687224647,"version":"3.50.1"},"reference-count":10,"publisher":"The Journal of Rheumatology","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Rheumatol"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:sec><jats:title>Objective.<\/jats:title><jats:p>To evaluate the efficacy and safety of anakinra in inpatient management of acute gout and pseudogout.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>Hospitalized patients with acute gout (n = 77) or pseudogout (n = 11) or both (n = 3) were analyzed for response to anakinra and adverse effects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>Half of all patients had comorbidities limiting the treatment choice. Anakinra was well tolerated, and 92% of gout flares and 79% of pseudogout flares responded to treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion.<\/jats:title><jats:p>Anakinra is an effective and safe treatment for acute gout and pseudogout in hospitalized patients, particularly in those with comorbidities.<\/jats:p><\/jats:sec>","DOI":"10.3899\/jrheum.180393","type":"journal-article","created":{"date-parts":[[2018,11,15]],"date-time":"2018-11-15T07:26:45Z","timestamp":1542266805000},"page":"748-750","source":"Crossref","is-referenced-by-count":20,"title":["Utility of Anakinra in Acute Crystalline Diseases: A Retrospective Study Comparing a University Hospital with a Veterans Affairs Medical Center"],"prefix":"10.3899","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4803-3453","authenticated-orcid":false,"given":"Julianna","family":"Desmarais","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5642-4625","authenticated-orcid":false,"given":"Cong-Qiu","family":"Chu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2262","published-online":{"date-parts":[[2018,11,15]]},"reference":[{"key":"2019080920150979000_46.7.748.1","doi-asserted-by":"publisher","DOI":"10.1038\/nature04516"},{"key":"2019080920150979000_46.7.748.2","doi-asserted-by":"publisher","DOI":"10.1186\/ar2143"},{"key":"2019080920150979000_46.7.748.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2010.03.001"},{"key":"2019080920150979000_46.7.748.4","doi-asserted-by":"publisher","DOI":"10.1002\/acr.21989"},{"key":"2019080920150979000_46.7.748.5","doi-asserted-by":"publisher","DOI":"10.1186\/ar4303"},{"key":"2019080920150979000_46.7.748.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2012.07.018"},{"key":"2019080920150979000_46.7.748.7","doi-asserted-by":"crossref","first-page":"792173","DOI":"10.1155\/2015\/792173","article-title":"Efficacy of anakinra for various types of crystal-induced arthritis in complex hospitalized patients: a case series and review of the literature","volume":"2015","author":"Aouba","year":"2015","journal-title":"Mediators Inflamm"},{"key":"2019080920150979000_46.7.748.8","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2012-202380"},{"key":"2019080920150979000_46.7.748.9","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1007\/s10067-014-2601-7","article-title":"Anakinra treatment in patients with gout and type 2 diabetes","volume":"34","author":"Vitale","year":"2015","journal-title":"Clin Rheumatol"},{"key":"2019080920150979000_46.7.748.10","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.semarthrit.2015.02.006","article-title":"Anakinra for the treatment of acute severe gout in critically ill patients","volume":"45","author":"Thueringer","year":"2015","journal-title":"Semin Arthritis Rheum"}],"container-title":["The Journal of Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.3899\/jrheum.180393","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,9]],"date-time":"2019-08-09T23:15:40Z","timestamp":1565392540000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jrheum.org\/lookup\/doi\/10.3899\/jrheum.180393"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,15]]},"references-count":10,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2019,7,1]]},"published-print":{"date-parts":[[2019,7]]}},"alternative-id":["10.3899\/jrheum.180393"],"URL":"https:\/\/doi.org\/10.3899\/jrheum.180393","relation":{},"ISSN":["0315-162X","1499-2752"],"issn-type":[{"value":"0315-162X","type":"print"},{"value":"1499-2752","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,15]]}}}