{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:25:18Z","timestamp":1787030718314,"version":"build-2736575974"},"reference-count":30,"publisher":"The Journal of Rheumatology","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Rheumatol"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective.<\/jats:title>\n                    <jats:p>To examine the relationship between demographics, disease-related variables, treatment, and sexual quality of life (SQOL) in men and women with axial spondyloarthritis (axSpA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods.<\/jats:title>\n                    <jats:p>AxSpA patients were consecutively recruited from 2 rheumatology outpatient clinics in southern Norway. A broad spectrum of demographics, disease, treatment, and QOL data were systematically collected. SQOL was assessed using the SQOL-Female (SQOL-F) questionnaire (score range 18\u2013108). Appropriate statistical tests were applied for group comparison, and the association between independent variables and SQOL-F was examined using multiple linear regression analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results.<\/jats:title>\n                    <jats:p>A total of 360 (240 men, 120 women) axSpA patients with mean age 45.5 years and disease duration 13.9 years were included. Seventy-eight percent were married\/cohabiting, 26.7% were current smokers, 71.0% were employed, 86.0% performed &gt; 1-h exercise per week, and 88.0% were HLA-B27\u2013positive. Mean (SD) values for disease measures were C-reactive protein (CRP) 8.5 (12.1) mg\/l, Bath Ankylosing Spondylitis Disease Activity Index 3.1 (2.1), Bath Ankylosing Spondylitis Global Score (BAS-G) 3.8 (2.5), Bath Ankylosing Spondylitis Functional Index 2.7 (2.2), and Health Assessment Questionnaire 0.6 (0.5). The proportion of patients using nonsteroidal antiinflammatory drugs was 44.0%, synthetic disease-modifying antirheumatic drugs (DMARD) 5.0%, and biologic DMARD 24.0%. Mean (SD) total sum score for SQOL was 76.6 (11.3). In multivariate analysis, female sex, increased body mass index, measures reflecting disease activity (BAS-G and CRP), and current biologic treatment were independently associated with a lower SQOL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion.<\/jats:title>\n                    <jats:p>Our data suggest that inflammation in patients with axSpA even in the biologic treatment era reduces SQOL.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3899\/jrheum.180413","type":"journal-article","created":{"date-parts":[[2019,2,15]],"date-time":"2019-02-15T12:20:26Z","timestamp":1550233226000},"page":"1075-1083","source":"Crossref","is-referenced-by-count":14,"title":["Sexual Quality of Life in Patients with Axial Spondyloarthritis in the Biologic Treatment Era"],"prefix":"10.3899","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9612-2747","authenticated-orcid":false,"given":"Kari Hansen","family":"Berg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8538-7237","authenticated-orcid":false,"given":"Gudrun Elin","family":"Rohde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Pr\u00f8ven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esben Esther Pirelli","family":"Benestad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"\u00d8stensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glenn","family":"Haugeberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2262","published-online":{"date-parts":[[2019,2,15]]},"reference":[{"key":"2019090109250719000_46.9.1075.1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-010-1406-5"},{"key":"2019090109250719000_46.9.1075.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2004.01.002"},{"key":"2019090109250719000_46.9.1075.3","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4755-10-25"},{"key":"2019090109250719000_46.9.1075.4","unstructured":"Spilker B , editor. 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