{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T16:23:57Z","timestamp":1790526237212,"version":"4.1.0"},"reference-count":18,"publisher":"The Journal of Rheumatology","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Rheumatol"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:sec><jats:title>Objective.<\/jats:title><jats:p>To explore the role of smoking and obesity in primary Sj\u00f6gren syndrome (pSS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>Olmsted County (Minnesota, USA) residents (n = 106) diagnosed with pSS from 2000 to 2015 were compared to 3 controls without pSS and matched for age and sex who were randomly selected from Olmsted County residents.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>Current smokers were less likely to be pSS cases (OR 0.34, 95% CI 0.14\u20130.85), while there was no association between former smoking and case\/control status (OR 1.27, 95% CI 0.80\u20132.03) compared to never smokers. Smoking status was not associated with antinuclear antibody, anti-SSA, anti-SSB, or rheumatoid factor positivity (p &gt; 0.05). OR for obesity was 0.79 (95% CI 0.48\u20131.30).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion.<\/jats:title><jats:p>In this population-based study, current smoking was inversely associated with case\/control status, while body mass index lacked any association.<\/jats:p><\/jats:sec>","DOI":"10.3899\/jrheum.180481","type":"journal-article","created":{"date-parts":[[2019,1,15]],"date-time":"2019-01-15T12:38:18Z","timestamp":1547555898000},"page":"727-730","source":"Crossref","is-referenced-by-count":19,"title":["Association of Smoking and Obesity on the Risk of Developing Primary Sj\u00f6gren Syndrome: A Population-based Cohort 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