{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T05:20:26Z","timestamp":1761110426472,"version":"3.37.3"},"reference-count":38,"publisher":"The Journal of Rheumatology","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Rheumatol"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:sec><jats:title>Objective.<\/jats:title><jats:p>The aim of this study was to examine the occurrence of repair in a cohort of conventionally treated patients with early rheumatoid arthritis over 8 years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>There were 395 patients included in the BARFOT study having radiographs of hands and feet at inclusion, and at 1, 2, 5, and 8 years, which were chronologically scored for erosions by the Sharp\/van der Heijde method. An erosion with repair was defined as an erosion that has become partially or totally filled, with or without sclerosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>Erosions with repair were observed in 64 patients (16%) at 1 year, 113 (29%) at 2 years, 142 (36%) at 5 years, and 200 (51%) at 8 years. At the 1-year visit, 13% of the patients with at least 1 new erosion showed repair versus 3% of the patients with no new erosions (p = 0.001). At 2, 5, and 8 years the corresponding figures were 22% and 6%, 28% and 8%, and 39% and 11%, respectively (all p = 0.001). The sum of all repaired erosions correlated strongly with the sum of all erosions and with the sum of all erosion scores (\u03c1 = 0.79 and 0.77). Presence of rheumatoid factor (RF) and anticyclic citrullinated peptide antibodies (anti-CCP) was significantly associated with both new erosions and repair.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion.<\/jats:title><jats:p>Repair was more common than previously described. The frequency of repair increased over time and was associated with the number of erosions. RF- and anti-CCP\u2013positivity, patient age, and presence of erosions at baseline were independent predictors of repair.<\/jats:p><\/jats:sec>","DOI":"10.3899\/jrheum.180557","type":"journal-article","created":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T12:34:24Z","timestamp":1549024464000},"page":"670-675","source":"Crossref","is-referenced-by-count":7,"title":["Repair of Erosions in Patients with Rheumatoid Arthritis"],"prefix":"10.3899","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1692-9597","authenticated-orcid":false,"given":"Kristina","family":"Forslind","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerstin","family":"Eberhardt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6501-2908","authenticated-orcid":false,"given":"Bj\u00f6rn","family":"Svensson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2262","published-online":{"date-parts":[[2019,2,1]]},"reference":[{"key":"2019080920150976000_46.7.670.1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780140605"},{"issue":"Suppl 2","key":"2019080920150976000_46.7.670.2","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1093\/rheumatology\/XXXIV.suppl_2.74","article-title":"Joint erosions and patients with early rheumatoid arthritis","volume":"34","author":"van der Heijde","year":"1995","journal-title":"Br J Rheumatol"},{"key":"2019080920150976000_46.7.670.3","doi-asserted-by":"publisher","DOI":"10.1016\/S0950-3579(96)80043-4"},{"key":"2019080920150976000_46.7.670.4","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1111\/j.1445-5994.1993.tb01806.x","article-title":"Better guidelines to rheumatoid arthritis therapy","volume":"23","author":"Edmonds","year":"1993","journal-title":"Aust N Z J Med"},{"key":"2019080920150976000_46.7.670.5","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.rheumatology.a031496"},{"key":"2019080920150976000_46.7.670.6","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60027-0"},{"key":"2019080920150976000_46.7.670.7","first-page":"1102","article-title":"Repair of erosions in rheumatoid arthritis does occur. 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