{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T20:25:49Z","timestamp":1781555149074,"version":"3.54.5"},"reference-count":39,"publisher":"The Journal of Rheumatology","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Rheumatol"],"published-print":{"date-parts":[[2020,7,1]]},"abstract":"<jats:sec><jats:title>Objective.<\/jats:title><jats:p>We examined the association between sleep and odds of developing knee pain, and whether this relationship varied by status of widespread pain (WSP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>At the 60-month visit of the Multicenter Osteoarthritis Study, sleep quality and restless sleep were each assessed by using a single item from 2 validated questionnaires. Each sleep measure was categorized into 3 levels, with poor\/most restless sleep as the reference. WSP was defined as pain above and below the waist on both sides of the body and axially using a standard homunculus, based on the American College of Rheumatology criteria. Outcomes from 60\u201384 months included (1) knee pain worsening (KPW; defined as minimal clinically important difference in WOMAC pain), (2) prevalent, and (3) incident consistent frequent knee pain. We applied generalized estimating equations in multivariable logistic regression models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>We studied 2329 participants (4658 knees; 67.9 yrs, body mass index 30.9]. We found that WSP modified the relationship between sleep quality and KPW (p = 0.002 for interaction). Among persons with WSP, OR (95% CI) for KPW was 0.53 (0.35\u20130.78) for those with very good sleep quality (p trend &lt; 0.001); additionally, we found the strongest association of sleep quality in persons with &gt; 8 painful joint sites (p trend &lt; 0.01), but not in those with \u2264 2 painful joint sites. Similar results were observed using restless sleep, in the presence of WSP. The cross-sectional relationship between sleep and prevalence of consistent frequent knee pain was significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion.<\/jats:title><jats:p>Better sleep was related to less KPW with coexisting widespread pain.<\/jats:p><\/jats:sec>","DOI":"10.3899\/jrheum.181365","type":"journal-article","created":{"date-parts":[[2019,11,15]],"date-time":"2019-11-15T17:22:24Z","timestamp":1573838544000},"page":"1019-1025","source":"Crossref","is-referenced-by-count":35,"title":["Sleep Quality Is Related to Worsening Knee Pain in Those with Widespread Pain: The Multicenter Osteoarthritis Study"],"prefix":"10.3899","volume":"47","author":[{"given":"Zhaoli","family":"Dai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuhina","family":"Neogi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carrie","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Nevitt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cora E.","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Torner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David T.","family":"Felson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2262","published-online":{"date-parts":[[2019,11,15]]},"reference":[{"key":"2023121610203132000_47.7.1019.1","doi-asserted-by":"publisher","DOI":"10.1002\/art.22292"},{"key":"2023121610203132000_47.7.1019.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cger.2010.03.001"},{"key":"2023121610203132000_47.7.1019.3"},{"key":"2023121610203132000_47.7.1019.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2005.05.002"},{"key":"2023121610203132000_47.7.1019.5","doi-asserted-by":"publisher","DOI":"10.2522\/ptj.20130331"},{"key":"2023121610203132000_47.7.1019.6","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.160853"},{"key":"2023121610203132000_47.7.1019.7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2000.tb02597.x"},{"key":"2023121610203132000_47.7.1019.8","doi-asserted-by":"publisher","DOI":"10.1016\/S1087-0792(03)00044-3"},{"key":"2023121610203132000_47.7.1019.9","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2015.05.014"},{"key":"2023121610203132000_47.7.1019.10","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2011-201047"},{"key":"2023121610203132000_47.7.1019.11","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2010.196"},{"key":"2023121610203132000_47.7.1019.12","doi-asserted-by":"publisher","DOI":"10.1111\/j.2044-8287.2011.02045.x"},{"key":"2023121610203132000_47.7.1019.13","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.1830"},{"key":"2023121610203132000_47.7.1019.14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2013.08.007"},{"key":"2023121610203132000_47.7.1019.15","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1002\/art.39051","article-title":"Characteristics of fibromyalgia independently predict poorer long-term analgesic outcomes following total knee and hip arthroplasty","volume":"67","author":"Brummett","year":"2015","journal-title":"Arthritis Rheumatol"},{"key":"2023121610203132000_47.7.1019.16","doi-asserted-by":"publisher","DOI":"10.1002\/art.33346"},{"key":"2023121610203132000_47.7.1019.17","first-page":"513","article-title":"The role of sleep in pain and fibromyalgia","volume":"11","author":"Choy","year":"2015","journal-title":"Br J Health Psychol"},{"key":"2023121610203132000_47.7.1019.18","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1002\/art.38284","article-title":"Predictors of new-onset widespread pain in older adults: results from a population-based prospective cohort study in the UK","volume":"66","author":"McBeth","year":"2014","journal-title":"Arthritis Rheumatol"},{"key":"2023121610203132000_47.7.1019.19","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1002\/acr.22459","article-title":"Sleep disturbance in osteoarthritis: linkages with pain, disability, and depressive symptoms","volume":"67","author":"Parmelee","year":"2015","journal-title":"Arthritis Care Res"},{"key":"2023121610203132000_47.7.1019.20","doi-asserted-by":"crossref","unstructured":"Salwen JK Smith MT Finan PH . Mid-treatment sleep duration predicts clinically significant knee osteoarthritis pain reduction at 6 months: effects from a behavioral sleep medicine clinical trial. Sleep 2017;40:zsw064.","DOI":"10.1093\/sleep\/zsw064"},{"issue":"Suppl 107","key":"2023121610203132000_47.7.1019.21","first-page":"79","article-title":"The role of centralised pain in osteoarthritis","volume":"35","author":"Clauw","year":"2017","journal-title":"Clin Exp Rheumatol"},{"key":"2023121610203132000_47.7.1019.22","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmrj.2013.04.014"},{"key":"2023121610203132000_47.7.1019.23","first-page":"131","article-title":"Minimal clinically important rehabilitation effects in patients with osteoarthritis of the lower extremities","volume":"29","author":"Angst","year":"2002","journal-title":"J Rheumatol"},{"key":"2023121610203132000_47.7.1019.24","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20140"},{"key":"2023121610203132000_47.7.1019.25","doi-asserted-by":"publisher","DOI":"10.1037\/0882-7974.12.2.277"},{"key":"2023121610203132000_47.7.1019.26","doi-asserted-by":"crossref","unstructured":"Chen CJ McHugh G Campbell M Luker K . Subjective and objective sleep quality in individuals with osteoarthritis in Taiwan. Musculoskeletal Care 2014 Dec 10 (E-pub ahead of print).","DOI":"10.1002\/msc.1094"},{"key":"2023121610203132000_47.7.1019.27","doi-asserted-by":"publisher","DOI":"10.1002\/art.21584"},{"key":"2023121610203132000_47.7.1019.28","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2011.03544.x"},{"key":"2023121610203132000_47.7.1019.29","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1002\/art.39048","article-title":"Cognitive-behavioral therapy for insomnia in knee osteoarthritis: a randomized, double-blind, active placebo-controlled clinical trial","volume":"67","author":"Smith","year":"2015","journal-title":"Arthritis Rheumatol"},{"key":"2023121610203132000_47.7.1019.30","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/pme.12695","article-title":"The \u201ccontinuum of pain\u201d and the American Academy of Pain Medicine","volume":"16","author":"Mackey","year":"2015","journal-title":"Pain Med"},{"key":"2023121610203132000_47.7.1019.31","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1177\/0310057X1103900202","article-title":"The pain continuum: towards prevention and better management of pain","volume":"39","author":"Jones","year":"2011","journal-title":"Anaesth Intensive Care"},{"key":"2023121610203132000_47.7.1019.32","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-015-4575-4"},{"key":"2023121610203132000_47.7.1019.33","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.100743"},{"key":"2023121610203132000_47.7.1019.34","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-009-0073-2"},{"key":"2023121610203132000_47.7.1019.35","doi-asserted-by":"crossref","first-page":"e0169216","DOI":"10.1371\/journal.pone.0169216","article-title":"Associations of self-reported sleep quality with circulating interferon gamma-inducible protein 10, interleukin 6, and high-sensitivity C-reactive protein in healthy menopausal women","volume":"12","author":"Huang","year":"2017","journal-title":"PLoS One"},{"key":"2023121610203132000_47.7.1019.36","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2016.12.026"},{"key":"2023121610203132000_47.7.1019.37","doi-asserted-by":"publisher","DOI":"10.1002\/art.37733"},{"key":"2023121610203132000_47.7.1019.38","doi-asserted-by":"publisher","DOI":"10.1172\/JCI82755"},{"key":"2023121610203132000_47.7.1019.39","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.24946"}],"container-title":["The Journal of Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.3899\/jrheum.181365","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,16]],"date-time":"2023-12-16T18:20:46Z","timestamp":1702750846000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jrheum.org\/lookup\/doi\/10.3899\/jrheum.181365"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,15]]},"references-count":39,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2020,7,1]]},"published-print":{"date-parts":[[2020,7,1]]}},"alternative-id":["10.3899\/jrheum.181365"],"URL":"https:\/\/doi.org\/10.3899\/jrheum.181365","relation":{},"ISSN":["0315-162X","1499-2752"],"issn-type":[{"value":"0315-162X","type":"print"},{"value":"1499-2752","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,15]]}}}