{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T06:36:26Z","timestamp":1790145386253,"version":"4.0.1"},"reference-count":47,"publisher":"The Journal of Rheumatology","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Rheumatol"],"accepted":{"date-parts":[[2025,8,21]]},"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study investigates individual and socioecological resilience and its relationship with sociodemographic and disease characteristics, as well as psychosocial patient-reported outcome measures (PROMs) in childhood-onset systemic lupus erythematosus (cSLE).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a cross-sectional study of patients with cSLE, ages 11-22 years, at a Canadian tertiary center from October 2021 to July 2024. The 10-item Connor-Davidson Resilience Scale (CD-RISC-10) assessed individual resilience. The Child and Youth Resilience Measure\u2013Revised (CYRM-R) assessed socioecological resilience. Linear regression models examined associations between resilience with sociodemographic (eg, health literacy, adverse childhood experiences [ACEs]) and disease factors (eg, age of onset, duration, disease activity). Pearson correlations determined relationships between resilience and patient-reported depressive and anxiety symptoms, executive functioning, pain interference, and fatigue.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 49 participants, the mean score for individual psychological resilience was 26.0 (SD 7.1; CD-RISC-10), and the mean score for socioecological resilience was 73.4 (SD 9.1; CYRM-R). Higher resilience on CD-RISC-10 (\u03b2 0.99, 95% CI 0.45-1.55,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.01) and CYRM-R (\u03b2 0.84, 95% CI 0.13-1.55,\n                      <jats:italic>P<\/jats:italic>\n                      = 0.02) was associated with better health literacy on the communication subscale. Lower CYRM-R scores were associated with higher number of ACEs (\u03b2 \u22121.02, 95% CI \u22121.88 to \u22120.17;\n                      <jats:italic>P<\/jats:italic>\n                      = 0.02). For PROMs, lower scores for both individual and socioecological resilience correlated with worse depressive symptoms (\n                      <jats:italic>r<\/jats:italic>\n                      \u22120.44,\n                      <jats:italic>P<\/jats:italic>\n                      = 0.003 for CD-RISC-10;\n                      <jats:italic>r<\/jats:italic>\n                      \u22120.55,\n                      <jats:italic>P<\/jats:italic>\n                      = 0.001 for CYRM-R) and executive functioning (\n                      <jats:italic>r<\/jats:italic>\n                      \u22120.49,\n                      <jats:italic>P<\/jats:italic>\n                      = 0.002 for CD-RISC-10;\n                      <jats:italic>r<\/jats:italic>\n                      \u22120.56,\n                      <jats:italic>P<\/jats:italic>\n                      = 0.002 for CYRM-R).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Greater resilience was associated with fewer ACEs and better health-related communication, patient-reported mental health, and executive functioning. Findings highlight the importance of fostering resilience to improve outcomes in youth with cSLE.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3899\/jrheum.2025-0375","type":"journal-article","created":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T12:20:21Z","timestamp":1756729221000},"page":"297-306","source":"Crossref","is-referenced-by-count":2,"title":["Individual and Socioecological Resilience in Childhood-Onset Systemic Lupus Erythematosus: Associations With Patient Characteristics and Psychosocial Patient-Reported 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