{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T14:27:23Z","timestamp":1777904843775,"version":"3.51.4"},"reference-count":36,"publisher":"The Journal of Rheumatology","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Rheumatol"],"accepted":{"date-parts":[[2025,11,5]]},"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Rheumatoid arthritis (RA) is a potentially devastating autoimmune disease associated with multiple comorbidities, including osteoporosis and cardiovascular disease, which exert significant morbidity and mortality burdens. Despite the recognized connection between RA and fracture risk, few studies have evaluated postfracture survival in RA, and no studies have evaluated the effect of RA on postfracture survival between 1990 and 2010, when there was a rapid growth in disease-modifying antirheumatic drug (DMARD) availability in combination with a paradigm shift in the understanding of RA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a case-control matched retrospective cohort study of 1304 patients with RA, using routinely collected administrative health data from public and private hospitals in Western Australia, to assess survival after a first fracture.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We found that RA associated with a significant survival disadvantage after fracture (hazard ratio [HR] for death 1.28, 95% CI 1.18-1.39). In contrast to expectations, postfracture survival did not improve from 1990-1999 to 2000-2010 in patients with RA or in controls (HR: RA 0.95, 95% CI 0.75-1.20 vs controls 0.86, 95% CI 0.71-1.04). Further, we found that RA is a risk factor for increased episodes of hospital-based care (odds ratio 1.27, 95% CI 1.08-1.48).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Using data from hospitals in Western Australia, this study demonstrates that people with RA have worse survival after fracture, and, in contrast to expectation, this survival has not improved despite significant therapeutic advances over the past 40 years. Consequently, this study emphasizes the need to better understand and treat fractures in RA to improve the lives of these patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3899\/jrheum.2025-0635","type":"journal-article","created":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T13:20:17Z","timestamp":1763212817000},"page":"495-500","source":"Crossref","is-referenced-by-count":0,"title":["Association of Rheumatoid Arthritis With Postfracture Mortality and Fracture-Related Care"],"prefix":"10.3899","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7021-7588","authenticated-orcid":false,"given":"Owen","family":"Taylor-Williams","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2833-7997","authenticated-orcid":false,"given":"Johannes","family":"Nossent","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0535-963X","authenticated-orcid":false,"given":"Charles A.","family":"Inderjeeth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2262","published-online":{"date-parts":[[2025,11,15]]},"reference":[{"key":"2026050105301087000_53.5.495.1","doi-asserted-by":"crossref","first-page":"2235042X19853484","DOI":"10.1177\/2235042X19853484","article-title":"Morbidity and mortality in patients with rheumatoid arthritis compared with an age- and sex-matched control population: a nationwide register study","volume":"9","author":"L\u00f8ppenthin","year":"2019","journal-title":"J Comorb"},{"key":"2026050105301087000_53.5.495.2","doi-asserted-by":"crossref","first-page":"e16286","DOI":"10.1097\/MD.0000000000016286","article-title":"Do rheumatoid arthritis patients have more major complications and length of stay after lower extremities fracture surgery?: a nationwide data with propensity score matching","volume":"98","author":"Hsu","year":"2019","journal-title":"Medicine"},{"key":"2026050105301087000_53.5.495.3","doi-asserted-by":"publisher","DOI":"10.1097\/00002281-200307000-00016"},{"key":"2026050105301087000_53.5.495.4","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1080\/14656566.2020.1787381","article-title":"Osteoporosis in patients with rheumatoid arthritis: an update in epidemiology, pathogenesis, and fracture prevention","volume":"21","author":"Raterman","year":"2020","journal-title":"Expert Opin Pharmacother"},{"key":"2026050105301087000_53.5.495.5","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1007\/s00198-014-2968-y","article-title":"Rheumatoid arthritis patients with hip fracture: a nationwide study","volume":"26","author":"Lin","year":"2015","journal-title":"Osteoporos Int"},{"key":"2026050105301087000_53.5.495.6","doi-asserted-by":"crossref","first-page":"e2438","DOI":"10.1210\/clinem\/dgac092","article-title":"Fragility fractures in postmenopausal women: development of 5-year prediction models using the Frisbee study","volume":"107","author":"Baleanu","year":"2022","journal-title":"J Clin Endocrinol Metab"},{"key":"2026050105301087000_53.5.495.7","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1177\/15589447211049521","article-title":"Future fracture risk in upper extremity fracture and non-fracture patients","volume":"18","author":"Seyok","year":"2022","journal-title":"Hand"},{"key":"2026050105301087000_53.5.495.8","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-017-1403-x"},{"key":"2026050105301087000_53.5.495.9","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s11657-022-01139-0","article-title":"Trends in osteoporosis diagnosis and management in Australia","volume":"17","author":"Smith","year":"2022","journal-title":"Arch Osteoporos"},{"key":"2026050105301087000_53.5.495.10","doi-asserted-by":"publisher","DOI":"10.1097\/gme.0b013e3181e77468"},{"key":"2026050105301087000_53.5.495.11","doi-asserted-by":"crossref","first-page":"2603","DOI":"10.1007\/s10067-018-4218-8","article-title":"The association between 10-year fracture risk by FRAX and osteoporotic fractures with disease activity in patients with rheumatoid arthritis","volume":"37","author":"Phuan-Udom","year":"2018","journal-title":"Clin Rheumatol"},{"key":"2026050105301087000_53.5.495.12","doi-asserted-by":"publisher","DOI":"10.1186\/ar3107"},{"key":"2026050105301087000_53.5.495.13","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1007\/s12325-018-0686-0","article-title":"Perioperative management of patients with inflammatory rheumatic diseases undergoing major orthopaedic surgery: a practical overview","volume":"35","author":"Gualtierotti","year":"2018","journal-title":"Adv Ther"},{"key":"2026050105301087000_53.5.495.14","unstructured":"Independent Health and Aged Care Pricing Authority . 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