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Here we describe our clinical experience of the initial 50 LVAD patients from a single center.Methods: A total of 50 patients underwent LVAD implantation as bridge to transplantation (BTT; n = 28, 56%), bridge to candidacy (BTC; n = 2, 4%), or as destination therapy (DT; n = 20, 40%) from 2012 to 2019. Pre-implant characteristics and clinical outcomes were compared between BTT\/BTC and DT.Results: The median age of patients was 67 years (range, 59 to 73). Men were more likely to receive LVAD (76% vs. 24%) than women. DT patients were older, had smaller body surface area, and worse laboratory profiles than BTT\/BTC patients. There was no in-hospital mortality. During an average of 14 months (range, 8 to 23), the all-cause mortality was 22%. The first-year survival was 86 and 90% in BTT\/BTC and DT groups, respectively. Hemorrhagic stroke was the most common cause (27%) of death. In the BTT\/BTC group, 22 patients successfully underwent heart transplantation during median duration of 10 months (range, 7 to 14). The most common post-LVAD complication during the first year of LVAD implantation was major bleeding (44%). A significant proportion (76%) of patients experienced rehospitalization with gastrointestinal bleeding as the most common cause.Conclusions: We describe short-term clinical outcome of LVAD patients from a single center for the first time in Korea. With the newer generation LVAD and a dedicated team approach, improved clinical outcomes of LVAD for end-stage HF are expected.<\/jats:p>","DOI":"10.3904\/kjim.2021.088","type":"journal-article","created":{"date-parts":[[2021,12,6]],"date-time":"2021-12-06T23:30:18Z","timestamp":1638833418000},"page":"340-349","update-policy":"https:\/\/doi.org\/10.3904\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Clinical outcome in patients with end-stage heart failure who underwent continuous-flow left ventricular assist devices in a single center"],"prefix":"10.3904","volume":"37","author":[{"given":"Yoonjee","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3284-0904","authenticated-orcid":true,"given":"Darae","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong Hoon","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang Hyun","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Oh","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun-Seok","family":"Jeon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2270","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.4070\/kcj.2016.46.5.658"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.36628\/ijhf.2019.0002"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2020.120"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.4070\/kcj.2018.0392"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.36628\/ijhf.2020.0011"},{"key":"ref6","volume-title":"","year":"2019"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.4070\/kcj.2019.0161"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/s0735-1097(02)01751-5"},{"key":"ref9","first-page":"II83","volume-title":"Implantable left ventricular assist device. 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