{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T16:33:38Z","timestamp":1773765218557,"version":"3.50.1"},"reference-count":19,"publisher":"Korean Association of Internal Medicine","issue":"5","license":[{"start":{"date-parts":[[2023,7,7]],"date-time":"2023-07-07T00:00:00Z","timestamp":1688688000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"name":"Genoss Company Limited"}],"content-domain":{"domain":["kjim.org"],"crossmark-restriction":true},"short-container-title":["Korean J Intern Med"],"published-print":{"date-parts":[[2023,9,1]]},"abstract":"<jats:p>Background\/Aims: The Genoss DES\u2122 is a novel, biodegradable, polymer-coated, sirolimus-eluting stent with a cobalt- chromium stent platform and thin strut. Although the safety and effectiveness of this stent have been previously investigated, real-world clinical outcomes data are lacking. Therefore, the aim of this prospective, multicenter trial was to evaluate the clinical safety and effectiveness of the Genoss DES\u2122 in all-comer patients undergoing percutaneous coronary intervention.Methods: The Genoss DES registry is a prospective, single-arm, observational trial for evaluation of clinical outcomes after Genoss DES\u2122 implantation in all-comer patients undergoing percutaneous coronary intervention from 17 sites in South Korea. The primary endpoint was a device-oriented composite outcome of cardiac death, target vessel-related myocardial infarction (MI), and clinically driven target lesion revascularization (TLR) at 12 months.Results: A total of 1,999 patients (66.4 \u00b1 11.1 years of age; 72.8% male) were analyzed. At baseline, 62.8% and 36.7% of patients had hypertension and diabetes, respectively. The implanted stent number, diameter, and length per patient were 1.5 \u00b1 0.8, 3.1 \u00b1 0.5 mm, and 37.0 \u00b1 25.0 mm, respectively. The primary endpoint occurred in 1.8% patients, with a cardiac death rate of 1.1%, target vessel-related MI rate of 0.2%, and clinically driven TLR rate of 0.8%.Conclusions: In this real-world registry, the Genoss DES\u2122 demonstrated excellent safety and effectiveness at 12 months among all-comer patients undergoing percutaneous coronary intervention. These findings suggest that the Genoss DES\u2122 may be a viable treatment option for patients with coronary artery disease.<\/jats:p>","DOI":"10.3904\/kjim.2023.129","type":"journal-article","created":{"date-parts":[[2023,7,7]],"date-time":"2023-07-07T01:35:47Z","timestamp":1688693747000},"page":"683-691","update-policy":"https:\/\/doi.org\/10.3904\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Clinical safety and effectiveness of the Genoss drug-eluting stent in real-world clinical practice"],"prefix":"10.3904","volume":"38","author":[{"given":"Young Jin","family":"Youn","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun-Won","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung 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