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Despite this, vaccination rates among patients with IBD remain low. Shingrix, a recombinant zoster vaccine, is generally preferred because of its high efficacy (&gt; 90%) and safety profile in immunocompromised individuals, unlike the live attenuated zoster vaccine (Zostavax). This review underscores the importance of HZ vaccination for patients aged \u2265 50 years, as well as for younger patients receiving high-risk therapies such as JAK inhibitors. Tailored vaccination strategies based on individual risk factors, including disease severity, medication use, and ethnicity, may enhance prevention. Given the higher incidence of HZ in certain populations, such as those in Korea, vaccination recommendations should be adapted accordingly. Further research is needed to evaluate the long-term effectiveness of Shingrix in younger patients with IBD to ensure sustained protection and prevent complications, such as postherpetic neuralgia.<\/jats:p>","DOI":"10.3904\/kjim.2024.342","type":"journal-article","created":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T07:25:51Z","timestamp":1745997951000},"page":"347-356","update-policy":"https:\/\/doi.org\/10.3904\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Herpes zoster infection in patients with inflammatory bowel disease"],"prefix":"10.3904","volume":"40","author":[{"given":"Dong 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