{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T02:53:44Z","timestamp":1784602424333,"version":"3.55.0"},"reference-count":27,"publisher":"Korean Association of Internal Medicine","issue":"3","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002560","name":"Soonchunhyang University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002560","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["kjim.org"],"crossmark-restriction":true},"short-container-title":["Korean J Intern Med"],"published-print":{"date-parts":[[2026,5,1]]},"abstract":"<jats:p>Background\/Aims: Few studies have compared modified endoscopic mucosal resection (EMR) techniques for small rectal neuroendocrine tumors (NETs). This study evaluated the clinical outcomes of ligation-assisted EMR (EMR-L) and precutting EMR (EMR-P) for the treatment of small rectal NETs.Methods: We retrospectively reviewed patients who underwent EMR-L or EMR-P for rectal NETs \u2264 10 mm at four university hospitals between January 2018 and December 2022. Primary outcomes were en bloc resection and complete resection rates; secondary outcomes included procedural time and complications.Results: Among a total of 195 rectal NETs, 143 were resected using EMR-L and 52 using EMR-P. Although the histopathologically measured lesion size (4.0 \u00b1 1.7 mm vs. 5.2 \u00b1 2.4 mm, p = 0.002) was larger in the EMR-P group, the presence of ulcer or depression and lesion location did not significantly differ between the two groups. The en bloc resection rate (100.0% vs. 96.2%, p = 0.070) and complete resection rate (95.8% vs. 90.4%, p = 0.140) also were not significantly different. However, EMR-L had a significantly shorter procedure time (3.9 \u00b1 2.3 min vs. 9.8 \u00b1 5.6 min, p &lt; 0.001). No significant differences were observed in procedure-related bleeding, perforation, recurrence, or hospital stay between the groups.Conclusions: Both EMR-L and EMR-P achieved high en bloc and complete resection rates with favorable safety profiles. However, EMR-L was significantly faster, suggesting that it is a more time-efficient approach for small rectal NET resection.<\/jats:p>","DOI":"10.3904\/kjim.2025.234","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T07:53:44Z","timestamp":1777535624000},"page":"432-440","update-policy":"https:\/\/doi.org\/10.3904\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Comparison between ligation-assisted and precutting endoscopic mucosal resection for small rectal neuroendocrine tumors: a CHASID study"],"prefix":"10.3904","volume":"41","author":[{"given":"Sunghyeok","family":"Ryou","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Dankook University Hospital, Dankook University College of Medicine, Cheonan, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7760-0050","authenticated-orcid":true,"given":"Yunho","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dae Sung","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hee Seok","family":"Moon","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hoon Sup","family":"Koo","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Deok","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Dankook University Hospital, Dankook University College of Medicine, Cheonan, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ki Bae","family":"Bang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Dankook University Hospital, Dankook University College of Medicine, Cheonan, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyu Chan","family":"Huh","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Chungcheong-Daejeon Association for the Study of Intestinal 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