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As the respiratory system serves as the primary entry route for inhaled pollutants, extensive evidence has demonstrated the detrimental effects of various air pollutants on respiratory health. Air pollution is a well-established risk factor for the development, exacerbation, and mortality of chronic respiratory diseases (CRDs), including airway diseases such as asthma, chronic obstructive pulmonary disease, interstitial lung disease, and lung cancer. This review summarizes the epidemiological evidence linking air pollution to the incidence and progression of CRDs and examines the impact of air quality control interventions. With the growing recognition that air pollution is a potentially preventable risk factor contributing to high morbidity and mortality, increasing attention has been directed toward protective strategies. 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