{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T22:32:36Z","timestamp":1790548356961,"version":"4.1.0"},"reference-count":65,"publisher":"CAIRN","issue":"HS1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,5,13]]},"abstract":"<jats:p>Les donn\u00e9es \u00e9pid\u00e9miologiques des infections transmises par les tiques, en particulier celles concernant la borr\u00e9liose de Lyme, sont h\u00e9t\u00e9rog\u00e8nes tant qualitativement que quantitativement. La borr\u00e9liose de Lyme est une zoonose transmise par les tiques du genre Ixodes ricinus . Apr\u00e8s piq\u00fbre de tique, le risque de transmission d\u2019un agent infectieux reste faible, le plus souvent repr\u00e9sent\u00e9 par Borrelia burgdorferi sensu lato \u00a0; des autres infections de l\u2019homme par plusieurs agents infectieux vari\u00e9s (bact\u00e9riens, viraux ou parasitaires) voire des co\u00efnfections sont possibles mais a priori rares. \u00c0 c\u00f4t\u00e9 des pathog\u00e8nes connus, de nouvelles esp\u00e8ces ou genres de micro-organismes sont r\u00e9guli\u00e8rement d\u00e9crits dans les tiques, mais on manque de donn\u00e9es sur la comp\u00e9tence vectorielle d\u2019 I.\u00a0ricinus pour ces nouveaux agents infectieux, pour pouvoir conclure sur leur \u00e9ventuelle pathog\u00e9nicit\u00e9 en m\u00e9decine humaine, qui n\u2019est pas d\u00e9crite ou n\u2019est pas encore \u00e9tablie \u00e0 ce jour. La pr\u00e9sentation clinique de la borr\u00e9liose de Lyme est vari\u00e9e, avec des formes localis\u00e9es et diss\u00e9min\u00e9es survenant \u00e0 distance de la piq\u00fbre de tique, rendant son diagnostic parfois difficile. L\u2019\u00e9volution naturelle de la borr\u00e9liose en l\u2019absence de traitement est peu connue\u00a0; cependant quelques \u00e9tudes historiques semblent rassurantes avec une gu\u00e9rison spontan\u00e9e possible et des s\u00e9quelles paraissant plut\u00f4t mineures. Le diagnostic des formes diss\u00e9min\u00e9es n\u00e9cessite des examens paracliniques, avec en premier lieu la s\u00e9rologie, dont la sensibilit\u00e9 augmente avec le temps d\u2019\u00e9volution de la borr\u00e9liose\u00a0; cela est d\u2019autant plus utile que les formes diss\u00e9min\u00e9es sont de diagnostic clinique plus difficile. Apr\u00e8s antibioth\u00e9rapie, l\u2019\u00e9volution clinique est bonne, les s\u00e9quelles restent possibles en particulier en cas de retard diagnostic ou de forme diss\u00e9min\u00e9e tardive\u00a0; leur fr\u00e9quence reste toutefois m\u00e9connue.<\/jats:p>","DOI":"10.3917\/spub.190.0051","type":"journal-article","created":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T00:25:34Z","timestamp":1559003134000},"page":"51-63","source":"Crossref","is-referenced-by-count":6,"title":["\u00c9pid\u00e9miologie de la borr\u00e9liose de Lyme en France\u00a0: entre incertitudes et certitudes"],"prefix":"10.3917","volume":"S1","author":[{"given":"Timoth\u00e9e","family":"Klopfenstein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beno\u00eet","family":"Jaulhac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Blanchon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Hansmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Chirouze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2273","reference":[{"key":"rb1","doi-asserted-by":"crossref","unstructured":"1Adeolu M, Gupta RS. A phylogenomic and molecular marker based proposal for the division of the genus Borrelia into two genera: the emended genus Borrelia containing only the members of the relapsing fever Borrelia, and the genus Borreliella gen. nov. containing the members of the Lyme disease Borrelia (Borrelia burgdorferi sensu lato complex). Antonie Van Leeuwenhoek. 2014;105(6):1049-72.","DOI":"10.1007\/s10482-014-0164-x"},{"key":"rb2","doi-asserted-by":"crossref","unstructured":"2Rudenko N, Golovchenko M, Grubhoffer L, Oliver JH. Updates on Borrelia burgdorferi sensu lato complex with respect to public health. Ticks Tick-Borne Dis. 2011;2(3):123-8.","DOI":"10.1016\/j.ttbdis.2011.04.002"},{"key":"rb3","doi-asserted-by":"crossref","unstructured":"3Pritt BS, Mead PS, Johnson DKH, Neitzel DF, Respicio-Kingry LB, Davis JP, et al. Identification of a novel pathogenic Borrelia species causing Lyme borreliosis with unusually high spirochaetaemia: a descriptive study. Lancet Infect Dis. 2016;16(5):556-64.","DOI":"10.1016\/S1473-3099(15)00464-8"},{"key":"rb4","doi-asserted-by":"crossref","unstructured":"4Boyer PH, De Martino SJ, Hansmann Y, Zilliox L, Boulanger N, Jaulhac B. No evidence of Borrelia mayonii in an endemic area for Lyme borreliosis in France. Parasit Vectors. 2017;10(1):282.","DOI":"10.1186\/s13071-017-2212-7"},{"key":"rb5","doi-asserted-by":"crossref","unstructured":"5Kurtenbach K, De Michelis S, Etti S, Sch\u00e4fer SM, Sewell H-S, Brade V, et al. Host association of Borrelia burgdorferi sensu lato--the key role of host complement. Trends Microbiol. 2002;10(2):74-9.","DOI":"10.1016\/S0966-842X(01)02298-3"},{"key":"rb6","doi-asserted-by":"crossref","unstructured":"6Heyman P, Cochez C, Hofhuis A, van der Giessen J, Sprong H, Porter\u00a0SR, et al. A clear and present danger: tick-borne diseases in Europe. Expert Rev Anti Infect Ther. 2010;8(1):33-50.","DOI":"10.1586\/eri.09.118"},{"key":"rb7","doi-asserted-by":"crossref","unstructured":"7Tomkins JL, Aungier J, Hazel W, Gilbert L. Towards an evolutionary understanding of questing behaviour in the tick Ixodes ricinus. PloS One. 2014;9(10):e110028.","DOI":"10.1371\/journal.pone.0110028"},{"key":"rb8","doi-asserted-by":"crossref","unstructured":"8Rizzoli A, Silaghi C, Obiegala A, Rudolf I, Hub\u00e1lek Z, F\u00f6ldv\u00e1ri G, et\u00a0al. Ixodes ricinus and its transmitted pathogens in urban and peri-urban areas in Europe: New Hazards and Relevance for Public Health. Front Public Health. 2014;2:251.","DOI":"10.3389\/fpubh.2014.00251"},{"key":"rb9","unstructured":"9Goldstein V. Epid\u00e9miologie vectorielle de la borr\u00e9liose de Lyme en France [Th\u00e8se de doctorat]. Universit\u00e9 de Strasbourg; 2017. 216\u00a0p."},{"key":"rb10","doi-asserted-by":"crossref","unstructured":"10Daniel M, Mal\u00fd M, Danielov\u00e1 V, K\u0159\u00ed\u017e B, Nuttall P. Abiotic predictors and annual seasonal dynamics of Ixodes ricinus, the major disease vector of Central Europe. Parasit Vectors. 2015;8(1):478.","DOI":"10.1186\/s13071-015-1092-y"},{"key":"rb11","doi-asserted-by":"crossref","unstructured":"11Goldstein V, Boulanger N, Schwartz D, George J-C, Ertlen D, Zilliox L, et al. Factors responsible for Ixodes ricinus nymph abundance: Are soil features indicators of tick abundance in a French region where Lyme borreliosis is endemic? Ticks Tick-Borne Dis. 2018;9(4): 938-44.","DOI":"10.1016\/j.ttbdis.2018.03.013"},{"key":"rb12","unstructured":"12Anderson JF. Epizootiology of Lyme borreliosis. Scand J Infect Dis Suppl. 1991;77:23-34."},{"key":"rb13","doi-asserted-by":"crossref","unstructured":"13Swart A, Iba\u00f1ez-Justicia A, Buijs J, van Wieren SE, Hofmeester TR, Sprong H, et al. Predicting tick presence by environmental risk mapping. Front Public Health. 2014;2:238.","DOI":"10.3389\/fpubh.2014.00238"},{"key":"rb14","doi-asserted-by":"crossref","unstructured":"14Lane RS, Piesman J, Burgdorfer W. Lyme borreliosis: relation of its causative agent to its vectors and hosts in North America and Europe. Annu Rev Entomol. 1991;36:587-609.","DOI":"10.1146\/annurev.en.36.010191.003103"},{"key":"rb15","doi-asserted-by":"crossref","unstructured":"15Levi T, Kilpatrick AM, Mangel M, Wilmers CC. Deer, predators, and the emergence of Lyme disease. Proc Natl Acad Sci U S A. 2012;109:10942-7.","DOI":"10.1073\/pnas.1204536109"},{"key":"rb16","doi-asserted-by":"crossref","unstructured":"16Kilpatrick HJ, LaBonte AM, Stafford KC. The relationship between deer density, tick abundance, and human cases of Lyme disease in a residential community. J Med Entomol. 2014;51:777-84.","DOI":"10.1603\/ME13232"},{"key":"rb17","doi-asserted-by":"crossref","unstructured":"17Coipan EC, Jahfari S, Fonville M, Maassen CB, van der Giessen J, Takken W, et al. Spatiotemporal dynamics of emerging pathogens in questing Ixodes ricinus. Front Cell Infect Microbiol. 2013;3:36.","DOI":"10.3389\/fcimb.2013.00036"},{"key":"rb18","doi-asserted-by":"crossref","unstructured":"18Strnad M, H\u00f6nig V, R\u016f\u017eek D, Grubhoffer L, Rego ROM. Europe-Wide Meta-Analysis of Borrelia burgdorferi Sensu Lato Prevalence in Questing Ixodes ricinus Ticks. Appl Environ Microbiol. 2017;83:15.","DOI":"10.1128\/AEM.00609-17"},{"key":"rb19","unstructured":"19Serre A, Tessier A, Stoll J., 2017. \u00c9tude sur les maladies transmises par les tiques, Franche-Comt\u00e9, 2010-2012. Saint-Maurice\u00a0: Sant\u00e9 publique France. 52\u00a0p. \/ 2017 \/ Maladies infectieuses \/ Rapports et synth\u00e8ses \/ Publications et outils \/ Accueil [Internet]. [cited 2018 Mar 24]. Available from: http:\/\/invs.santepubliquefrance.fr\/Publications-et-outils\/Rapports-et-syntheses\/Maladies-infectieuses\/2017\/Etude-sur-les-maladies-transmises-par-les-tiques-Franche-Comte-2010-2012."},{"key":"rb20","unstructured":"20Septfons A, Paty MC, de Valk H, Couturier E, Gautier A. Pratiques de pr\u00e9vention et connaissance de la borr\u00e9liose de Lyme\u00a0: Barom\u00e8tre sant\u00e9 2016. Bull Epid\u00e9miol Hebd. 2018;419:19-20."},{"key":"rb21","unstructured":"21Carte [Internet]. Citique. [cited 2018 Mar 24]. Available from: https:\/\/www.citique.fr\/carte\/."},{"key":"rb22","doi-asserted-by":"crossref","unstructured":"22Moutailler S, Valiente Moro C, Vaumourin E, Michelet L, Tran FH, Devillers E, et al. Co-infection of Ticks: The Rule Rather Than the Exception. PLoS Negl Trop Dis. 2016;10:e0004539.","DOI":"10.1371\/journal.pntd.0004539"},{"key":"rb23","doi-asserted-by":"crossref","unstructured":"23Jahfari S, Hofhuis A, Fonville M, van der Giessen J, van Pelt W, Sprong H. Molecular Detection of Tick-Borne Pathogens in Humans with Tick Bites and Erythema Migrans, in the Netherlands. PLoS Negl Trop Dis. 2016;10:e0005042.","DOI":"10.1371\/journal.pntd.0005042"},{"key":"rb24","doi-asserted-by":"crossref","unstructured":"24Hofhuis A, van de Kassteele J, Sprong H, van den Wijngaard CC, Harms MG, Fonville M, et al. Predicting the risk of Lyme borreliosis after a tick bite, using a structural equation model. PloS One. 2017;12:e0181807.","DOI":"10.1371\/journal.pone.0181807"},{"key":"rb25","doi-asserted-by":"crossref","unstructured":"25Wilhelmsson P, Fryland L, Lindblom P, Sj\u00f6wall J, Ahlm C, Berglund J, et al. A prospective study on the incidence of Borrelia burgdorferi sensu lato infection after a tick bite in Sweden and on the \u00c5land Islands, Finland (2008-2009). Ticks Tick-Borne Dis. 2016;7:71-9.","DOI":"10.1016\/j.ttbdis.2015.08.009"},{"key":"rb26","unstructured":"26Bacon RM, Kugeler KJ, Mead PS, Centers for Disease Control and Prevention (CDC). Surveillance for Lyme disease--United States, 1992-2006. Morb Mortal Wkly Rep Surveill Summ Wash DC 2002. 2008;57:1-9."},{"key":"rb27","doi-asserted-by":"crossref","unstructured":"27Brownstein JS, Holford TR, Fish D. A climate-based model predicts the spatial distribution of the Lyme disease vector Ixodes scapularis in the United States. Environ Health Perspect. 2003;111:1152-7.","DOI":"10.1289\/ehp.6052"},{"key":"rb28","doi-asserted-by":"crossref","unstructured":"28Gray JS, Dautel H, Estrada-Pe\u00f1a A, Kahl O, Lindgren E. Effects of climate change on ticks and tick-borne diseases in Europe. Interdiscip Perspect Infect Dis. 2009;2009:593232.","DOI":"10.1155\/2009\/593232"},{"key":"rb29","doi-asserted-by":"crossref","unstructured":"29F\u00fcl\u00f6p B, Poggensee G. Epidemiological situation of Lyme borreliosis in Germany: surveillance data from six Eastern German States, 2002 to 2006. Parasitol Res. 2008;103(Suppl 1):S117-20.","DOI":"10.1007\/s00436-008-1060-y"},{"key":"rb30","doi-asserted-by":"crossref","unstructured":"30Smith R, Takkinen J. Lyme borreliosis: Europe-wide coordinated surveillance and action needed? Euro Surveill Bull Eur Sur Mal Transm Eur Commun Dis Bull. 2006;11(6):E060622.1.","DOI":"10.2807\/esw.11.25.02977-en"},{"key":"rb31","doi-asserted-by":"crossref","unstructured":"31Keesing F, Belden LK, Daszak P, Dobson A, Harvell CD, Holt RD, et\u00a0al. Impacts of biodiversity on the emergence and transmission of infectious diseases. Nature. 2010;468:647-52.","DOI":"10.1038\/nature09575"},{"key":"rb32","doi-asserted-by":"crossref","unstructured":"32Letrilliart L, Ragon B, Hanslik T, Flahault A. Lyme disease in France: a primary care-based prospective study. Epidemiol Infect. 2005;133:935-42.","DOI":"10.1017\/S0950268805004413"},{"key":"rb33","doi-asserted-by":"crossref","unstructured":"33Stanek G, Fingerle V, Hunfeld K-P, Jaulhac B, Kaiser R, Krause A, et\u00a0al. Lyme borreliosis: Clinical case definitions for diagnosis and management in Europe. Clin Microbiol Infect. 2011;17:69-79.","DOI":"10.1111\/j.1469-0691.2010.03175.x"},{"key":"rb34","unstructured":"34Donn\u00e9es \u00e9pid\u00e9miologiques \/ Borr\u00e9liose de lyme \/ Maladies \u00e0 transmission vectorielle \/ Maladies infectieuses \/ Dossiers th\u00e9matiques \/ Accueil [Internet]. [cited 2016 Aug 1]. Available from: http:\/\/www.invs.sante.fr\/Dossiers-thematiques\/Maladies-infectieuses\/Maladies-a-transmission-vectorielle\/Borreliose-de-lyme\/Donnees-epidemiologiques."},{"key":"rb35","doi-asserted-by":"crossref","unstructured":"35Enkelmann J, B\u00f6hmer M, fingerle V, Siffczyk C, WerberD, Littmann\u00a0M, et al. Incidence of notified Lyme borreliosis in Germany, 2013-2017. Scientific reports 2018;8:14976.","DOI":"10.1038\/s41598-018-33136-0"},{"key":"rb36","doi-asserted-by":"crossref","unstructured":"36Altpeter E, Zimmermann H, Oberreich J, P\u00e9ter O, Dvo\u0159\u00e1k C, Swiss Sentinel Surveillance Network. Tick related diseases in Switzerland, 2008 to 2011. Swiss Med Wkly. 2013;143:w13725.","DOI":"10.4414\/smw.2013.13725"},{"key":"rb37","doi-asserted-by":"crossref","unstructured":"37Vandenesch A, Turbelin C, Couturier E, Arena C, Jaulhac B, Ferquel\u00a0E, et al. Incidence and hospitalisation rates of Lyme borreliosis, France, 2004 to 2012. Euro Surveill Bull Eur Sur Mal Transm Eur Commun Dis Bull. 2014;19:34.","DOI":"10.2807\/1560-7917.ES2014.19.34.20883"},{"key":"rb38","doi-asserted-by":"crossref","unstructured":"38Raguet S, Le Strat Y, Chouin L, Hansmann Y, Martinot M, Kieffer P, et\u00a0al. Incidence de la borr\u00e9liose de Lyme dans les d\u00e9partements alsaciens, \u00e9tude Alsa(ce)tique, 2014-2015. Bull Epid\u00e9miol Hebd. 2018;406:19-20.","DOI":"10.1016\/j.medmal.2017.03.030"},{"key":"rb39","doi-asserted-by":"crossref","unstructured":"39Lipsker D, Hansmann Y, Limbach F, Clerc C, Tranchant C, Grunenberger F, et al. Disease expression of Lyme borreliosis in northeastern France. Eur J Clin Microbiol Infect Dis Off Publ Eur Soc Clin Microbiol. 2001;20:225-30.","DOI":"10.1007\/s100960100476"},{"key":"rb40","doi-asserted-by":"crossref","unstructured":"40Berglund J, Eitrem R, Ornstein K, Lindberg A, Ringn\u00e9r \u00c5, Elmrud H, et al. An Epidemiologic Study of Lyme Disease in Southern Sweden. N Engl J Med. 1995;333:1319-24.","DOI":"10.1056\/NEJM199511163332004"},{"key":"rb41","doi-asserted-by":"crossref","unstructured":"41Kindstrand E, Nilsson BY, Hovmark A, Nennesmo I, Pirskanen R, Solders G, et al. Polyneuropathy in late Lyme borreliosis - a clinical, neurophysiological and morphological description. Acta Neurol Scand. 2000;101:47-52.","DOI":"10.1034\/j.1600-0404.2000.00019.x"},{"key":"rb42","doi-asserted-by":"crossref","unstructured":"42Lenormand C, Jaulhac B, Debarbieux S, Dupin N, Granel-Brocard F, Adamski H, et al. Expanding the clinicopathological spectrum of late cutaneous Lyme borreliosis (acrodermatitis chronica atrophicans): A prospective study of 20 culture- and\/or polymerase chain reaction (PCR)-documented cases. J Am Acad Dermatol. 2016;74:685-92.","DOI":"10.1016\/j.jaad.2015.10.046"},{"key":"rb43","doi-asserted-by":"crossref","unstructured":"43Berende A, ter Hofstede HJM, Vos FJ, van Middendorp H, Vogelaar\u00a0ML, Tromp M, et al. Randomized Trial of Longer-Term Therapy for Symptoms Attributed to Lyme Disease. N Engl J Med. 2016;374:1209-20.","DOI":"10.1056\/NEJMoa1505425"},{"key":"rb44","doi-asserted-by":"crossref","unstructured":"44Fahrer H, Sauvain MJ, Zhioua E, Van Hoecke C, Gern LE. Longterm survey (7 years) in a population at risk for Lyme borreliosis: what happens to the seropositive individuals? Eur J Epidemiol. 1998;14:117-23.","DOI":"10.1023\/A:1007404620701"},{"key":"rb45","doi-asserted-by":"crossref","unstructured":"45Kuiper H, van Dam AP, Moll van Charante AW, Nauta NP, Dankert J. One year follow-up study to assess the prevalence and incidence of Lyme borreliosis among Dutch forestry workers. Eur J Clin Microbiol Infect Dis Off Publ Eur Soc Clin Microbiol. 1993;12:413-8.","DOI":"10.1007\/BF01967434"},{"key":"rb46","doi-asserted-by":"crossref","unstructured":"46Steere AC, Sikand VK, Meurice F, Parenti DL, Fikrig E, Schoen RT, et\u00a0al. Vaccination against Lyme disease with recombinant Borrelia burgdorferi outer-surface lipoprotein A with adjuvant. Lyme Disease Vaccine Study Group. N Engl J Med. 1998;339:209-15.","DOI":"10.1056\/NEJM199807233390401"},{"key":"rb47","doi-asserted-by":"crossref","unstructured":"47Asbrink E, Olsson I, Hovmark A. Erythema chronicum migrans Afzelius in Sweden. A study on 231 patients. Zentralbl Bakteriol Mikrobiol Hyg [A]. 1986;263(1-2):229-36.","DOI":"10.1016\/S0176-6724(86)80126-2"},{"key":"rb48","unstructured":"48Chodynicka B, Flisiak I, Lukaszuk C, Bu\u0142hak V. [Late consequences of untreated lyme borreliosis]. Przegl Epidemiol. 1997;51:445-9."},{"key":"rb49","doi-asserted-by":"crossref","unstructured":"49Roberg M, Forsberg P, Fryd\u00e9n A, Hederstedt B, Hyd\u00e9n D, Odkvist L. Long-term findings in patients with facial palsy and antibodies against Borrelia burgdorferi. Scand J Infect Dis. 1994;26:559-67.","DOI":"10.3109\/00365549409011814"},{"key":"rb50","doi-asserted-by":"crossref","unstructured":"50Niemann G, K\u00f6ksal MA, Oberle A, Michaelis R. Facial palsy and Lyme borreliosis: long-term follow-up of children with antibiotically untreated \u201cidiopathic\u201d facial palsy. Klin Padiatr. 1997;209:95-9.","DOI":"10.1055\/s-2008-1043935"},{"key":"rb51","doi-asserted-by":"crossref","unstructured":"51Kr\u00fcger H, Pulz M, Martin R, Sticht-Groh V. Long-term persistence of specific T- and B-lymphocyte responses to Borrelia burgdorferi following untreated neuroborreliosis. Infection. 1990;18:263-7.","DOI":"10.1007\/BF01646998"},{"key":"rb52","doi-asserted-by":"crossref","unstructured":"52Kristoferitsch W, Baumhackl U, Sluga E, Stanek G, Zeiler K. High-dose penicillin therapy in meningopolyneuritis Garin-Bujadoux-Bannwarth. Clinical and cerebrospinal fluid data. Zentralbl Bakteriol Mikrobiol Hyg. 1987;263(3):357-64.","DOI":"10.1016\/S0176-6724(87)80093-7"},{"key":"rb53","unstructured":"53Pfister HW, Wilske B, Preac V, Einh\u00e4upl KM. Clinical and serological follow up of patients with Bannwarth\u2019s syndrome: comparaison of patients with and without penicillin treatment. Zbl Bakt. 1989;Suppl.\u00a018:276-9."},{"key":"rb54","doi-asserted-by":"crossref","unstructured":"54Sindic CJ, Depre A, Bigaignon G, Goubau PF, Hella P, Laterre C. Lymphocytic meningoradiculitis and encephalomyelitis due to Borrelia burgdorferi: a clinical and serological study of 18 cases. J\u00a0Neurol Neurosurg Psychiatry. 1987;50:1565-71.","DOI":"10.1136\/jnnp.50.12.1565"},{"key":"rb55","doi-asserted-by":"crossref","unstructured":"55Kr\u00fcger H, Reuss K, Pulz M, Rohrbach E, Pflughaupt KW, Martin R, et\u00a0al. Meningoradiculitis and encephalomyelitis due to Borrelia burgdorferi: a follow-up study of 72 patients over 27 years. J Neurol. 1989;236:322-8.","DOI":"10.1007\/BF00314373"},{"key":"rb56","doi-asserted-by":"crossref","unstructured":"56Kindstrand E, Nilsson BY, Hovmark A, Pirskanen R, Asbrink E. Peripheral neuropathy in acrodermatitis chronica atrophicans \u2013 a late Borrelia manifestation. Acta Neurol Scand. 1997;95:338-45.","DOI":"10.1111\/j.1600-0404.1997.tb00222.x"},{"key":"rb57","doi-asserted-by":"crossref","unstructured":"57Dattwyler RJ, Luft BJ. Overview of the clinical manifestations of Borrelia burgdorferi infection. Can J Infect Dis J Can Mal Infect. 1991;2:61-3.","DOI":"10.1155\/1991\/902928"},{"key":"rb58","doi-asserted-by":"crossref","unstructured":"58Steere AC, Schoen RT, Taylor E. The clinical evolution of Lyme arthritis. 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Clin Microbiol Infect Off Publ Eur Soc Clin Microbiol Infect Dis. 2014 Oct;20:O786-7.","DOI":"10.1111\/1469-0691.12583"},{"key":"rb61","doi-asserted-by":"crossref","unstructured":"61Dessau RB, van Dam AP, Fingerle V, Gray J, Hovius JW, Hunfeld K-P, et al. To test or not to test? Laboratory support for the diagnosis of Lyme borreliosis: a position paper of ESGBOR, the ESCMID study group for Lyme borreliosis. Clin Microbiol Infect Off Publ Eur Soc Clin Microbiol Infect Dis. 2018;24:118-24.","DOI":"10.1016\/j.cmi.2017.08.025"},{"key":"rb62","doi-asserted-by":"crossref","unstructured":"62Leeflang MMG, Ang CW, Berkhout J, Bijlmer HA, Van Bortel W, Brandenburg AH, et al. The diagnostic accuracy of serological tests for Lyme borreliosis in Europe: a systematic review and meta-analysis. BMC Infect Dis. 2016;16:140.","DOI":"10.1186\/s12879-016-1468-4"},{"key":"rb63","doi-asserted-by":"crossref","unstructured":"63Knudtzen FC, Andersen NS, Jensen TG, Skarph\u00e9dinsson S. 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