{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T22:57:28Z","timestamp":1774565848603,"version":"3.50.1"},"reference-count":13,"publisher":"CAIRN.INFO","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,11]]},"abstract":"<jats:p>Introduction : Les manifestations cutan\u00e9es de la THA sont fr\u00e9quentes et presque m\u00e9connues des prestataires de sant\u00e9. L\u2019objectif de cette recherche \u00e9tait de d\u00e9crire les aspects \u00e9pid\u00e9mio-cliniques, th\u00e9rapeutiques et \u00e9volutifs des manifestations cutan\u00e9es de la THA. Patients et m\u00e9thodes : Il s\u2019agissait d\u2019une \u00e9tude ambispective descriptive et analytique, incluant les trypanosom\u00e9s pr\u00e9sentant des manifestations cutan\u00e9es, trait\u00e9s et suivis dans le centre du 1 er janvier 2018 au 31 d\u00e9cembre 2023. Les variables analys\u00e9es \u00e9taient \u00e9pid\u00e9miologiques, cliniques, paracliniques, th\u00e9rapeutiques et \u00e9volutives. R\u00e9sultats : La pr\u00e9valence des signes cutan\u00e9s \u00e9tait de 67,9 %, les donn\u00e9es les plus repr\u00e9sent\u00e9es \u00e9taient : la tranche d\u2019\u00e2ge \u2265 20 ans (74,4 %) avec un sex-ratio de 1,31 ; les activit\u00e9s \u00e0 moindre risque de THA (58,4 %), les patients passifs (55,2 %) ; les patients en phase II (99,2 %), le prurit (100 %) d\u2019intensit\u00e9 s\u00e9v\u00e8re (50 %), les l\u00e9sions de grattage (78,4 %) si\u00e9geant sur le thorax (82,6 %), les membres sup\u00e9rieurs (75,5 %) et inf\u00e9rieurs (54,1 %), et l\u2019abdomen (50,9 %) ; l\u2019abstinence th\u00e9rapeutique (82,4 %) et l\u2019association d\u2019autres maladies dermatologiques (23,2 %). L\u2019\u00e9volution moyenne des signes cutan\u00e9s \u00e9tait de six mois, au bout de deux mois en moyenne 96,7 % des patients suivis compl\u00e8tement \u00e9taient gu\u00e9ris. Les facteurs significatifs associ\u00e9s aux l\u00e9sions de grattage en analyse multivari\u00e9e \u00e9taient la localisation thoracique (p : 0,0006), la tranche d\u2019\u00e2ge de 0-19 ans (p : 0,03), les activit\u00e9s \u00e0 plus de risque de THA (p : 0,03) et la leucorachie \u2265 100cel\/\u00b5l (p : 0,01). Conclusion : Les l\u00e9sions de grattage sur le thorax sont tr\u00e8s pr\u00e9somptives de la THA.<\/jats:p>","DOI":"10.3917\/spub.251.0173","type":"journal-article","created":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T00:57:02Z","timestamp":1742345822000},"page":"173-181","source":"Crossref","is-referenced-by-count":0,"title":["Manifestations cutan\u00e9es de la trypanosomiase humaine africaine gambiense (THA)"],"prefix":"10.3917","volume":"vol. 37","author":[{"given":"Mamadou","family":"Camara","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ansoumane","family":"Kourouma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariama","family":"Layba Camara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mamadou","family":"Ba\u00eflo Diallo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Camara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mo\u00efse","family":"Kagbadouno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno","family":"Bucheton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2273","reference":[{"key":"rb1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.1997.00140.x"},{"key":"rb2","unstructured":"2Caumes E. La dermatologie tropicale change de visage. \u00c9ditorial. Bull Soc Pathol Exot. 2003;96(5):347-9."},{"key":"rb3","unstructured":"3Caumes E, Danis M, Mouchet J, Duflo B, Lagard\u00e8re B, Richard-LenobleD, et al. Trypanosomiases humaines africaines ou maladie du sommeil. In: Gentilini M. Dermatologie tropicale. 5e \u00e9dition. Paris, France: FLAMMARION; 1993. p. 123-34."},{"key":"rb4","unstructured":"4Ginoux PY, Frezil JL, Alary JC. La trypanosomiase humaine au moment du d\u00e9pistage en R\u00e9publique populaire du Congo. Distribution des signes cliniques. M\u00e9decine tropicale. 1982;42(3):281-87."},{"key":"rb5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0001358"},{"key":"rb6","doi-asserted-by":"publisher","DOI":"10.4414\/smw.2002.09902"},{"key":"rb7","unstructured":"7Boa YF, Traore MA, Doua F, Kouassi-Traore MT, Kouassi BE, Giordano C. Les diff\u00e9rents tableaux cliniques actuels de la trypanosomiase humaine africaine \u00e0 T.b. gambiense. Analyse de 300 dossiers du foyer de Daloa, C\u00f4te d\u2019Ivoire. Bulletin de la Soci\u00e9t\u00e9 de pathologie exotique.1988;8:427-44."},{"key":"rb8","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2005.08.001"},{"key":"rb9","unstructured":"9World Health Organization. Control and Surveillance of Human African Trypanosomiasis. World Health Organ Tech Rep Ser. 2013;(984):1-237."},{"key":"rb10","unstructured":"10Camara M, Kaba D, Kagbadouno M, Sanon JR, Ouendeno FF, Solano P. La trypanosomiase humaine africaine en zone de mangrove en R\u00e9publique de Guin\u00e9e : Caract\u00e9ristiques \u00e9pid\u00e9miologiques et cliniques de deux foyers voisins. Med Trop. 2005;65(2):155- 61."},{"key":"rb11","doi-asserted-by":"publisher","DOI":"10.1016\/j.annder.2008.09.023"},{"key":"rb12","unstructured":"12Kakou A, Assemian P, Eholie S, Bissagnene E, Coulibaly M, Aoussi E, et al. 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