{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T19:05:35Z","timestamp":1789067135062,"version":"build-2803163510"},"reference-count":33,"publisher":"Walter de Gruyter GmbH","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BM"],"published-print":{"date-parts":[[2011,9,1]]},"abstract":"<jats:p>The increasing incidence of antibiotic resistance among bacterial pathogens necessitates medicinal plants as an alternate therapy in restricting the resistant infectious organisms. In this primitive study, the antibiotic resistance of organisms isolated from urinary tract infected patients was evaluated using the National Committee for Clinical Laboratory Standards (NCCLS) method and Multiple Antibiotic Resistance (MAR) index values, and the MAR values was also calculated for plant extracts. The 10 common medicinal plants collected from Kolli hills, Namakkal, south India were extracted using the chloroform, methanol, acetone, ethanol and saponification procedure. The efficacy of the extracts on the uropathogens was tested by agar disc diffusion method in order to analyse the inhibitory activity of plant extract on the organisms.<jats:italic>Azadiracta indica<\/jats:italic>A. Juss.,<jats:italic>Tinospora cordifolia<\/jats:italic>(Wild.) and<jats:italic>Euphorbia hirta<\/jats:italic>Linn. exhibited high inhibitory activity against most of the 11 tested organisms followed by<jats:italic>Cassia javanica<\/jats:italic>Linn. and<jats:italic>Phyllanthus niruri<\/jats:italic>Linn. The maximum zone size of 46.3 mm was exhibited by methanol extract of<jats:italic>P. niruri<\/jats:italic>Linn. against<jats:italic>Pseudomonas aeruginosa. Asparagus racemosus Willd.<\/jats:italic>and<jats:italic>Eupatorium triplinerve<\/jats:italic>Vahl had the least activity against resistant pathogens. Saponified lipids of most of the plants exhibited maximum antibacterial activity. Among the tested organisms,<jats:italic>P. aeruginosa<\/jats:italic>and<jats:italic>Staphylococcus epidermidis<\/jats:italic>were the most susceptible and<jats:italic>Serratia marcescens, Enterobacter cloaceae, Citrobacter koseri<\/jats:italic>, and<jats:italic>Citrobacter freundii<\/jats:italic>were the least inhibited by most of the extracts of medicinal plants. It is concluded that revised antibiotic policies and more importantly the development of herbal medicine as an alternative may be incorporated in urological practice.<\/jats:p>","DOI":"10.3920\/bm2010.0033","type":"journal-article","created":{"date-parts":[[2011,10,11]],"date-time":"2011-10-11T01:06:37Z","timestamp":1318295197000},"page":"235-243","source":"Crossref","is-referenced-by-count":57,"title":["Antibacterial activity of selected medicinal plants against multiple antibiotic resistant uropathogens: a study from Kolli Hills, Tamil Nadu, India"],"prefix":"10.1163","volume":"2","author":[{"given":"A.","family":"Narayanan","sequence":"first","affiliation":[{"name":"PG and Research Department of Microbiology, K.S. Rangasamy College of Arts and Science, KSR Kalvi Nagar, Thokkavadi Post, Tiruchengode 637 215, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Raja","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Bharathidasan University College, Perambalur, Tiruchirapalli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Ponmurugan","sequence":"additional","affiliation":[{"name":"PG and Research Department of Microbiology, K.S. Rangasamy College of Arts and Science, KSR Kalvi Nagar, Thokkavadi Post, Tiruchengode 637 215, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Kandekar","sequence":"additional","affiliation":[{"name":"KSR Institute of Dental Science & Research, KSR Kalvi Nagar, Thokkavadi Post, Tiruchengode 637 215, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Natarajaseenivasan","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Bharathidasan University, Tiruchirapalli 620 024, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Maripandi","sequence":"additional","affiliation":[{"name":"Dept of Microbiology, Government Arts College, Dharmapuri 636 705, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Q.","family":"Mandeel","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Bahrain, P.O. 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