{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T12:13:13Z","timestamp":1777983193082,"version":"3.51.4"},"reference-count":31,"publisher":"Walter de Gruyter GmbH","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BM"],"published-print":{"date-parts":[[2016,11,30]]},"abstract":"<jats:p>Coccidiosis is regarded as the parasitic disease with the greatest economic impact on the poultry industry due to reduced performance and increased mortality. A study was conducted to investigate the effects of <jats:italic>in ovo<\/jats:italic> administration of probiotics on hatchability, performance, immune organ weights, and lesion scores in broiler chicks during a mixed <jats:italic>Eimeria<\/jats:italic> infection. At embryonic day 18, 210 eggs were injected with either sterile water or 1\u00d710<jats:sup>6<\/jats:sup> cfu probiotic bacteria. On day 3 post-hatch, half of the chicks from each treatment group were challenged with a mixed inoculum of <jats:italic>Eimeria<\/jats:italic>\n<jats:italic>acervulina<\/jats:italic>, <jats:italic>Eimeria<\/jats:italic>\n<jats:italic>maxima<\/jats:italic> and <jats:italic>Eimeria<\/jats:italic>\n<jats:italic>tenella<\/jats:italic>. Measurements and tissue samples were taken on day of hatch (DOH) and days 3, 9 and 15. On day 9, 24 birds per treatment were scored for intestinal <jats:italic>Eimeria<\/jats:italic> lesions. No differences were seen among groups for hatchability as well as for body weight (BW), BW gain (BWG), or immune organ weights prior to the <jats:italic>Eimeria<\/jats:italic> challenge. On day 9, the non-challenged birds with probiotic supplementation had higher BW and BWG than the non-supplemented controls while no differences were seen among the challenged groups. On day 15, probiotic supplemented birds had improved BW compared to the non-supplemented birds as well as increased BWG from day 9 to 15. Bursa weight was not affected by treatment at any time point while spleen weight was greater in supplemented birds on day 15. Birds receiving the probiotic had significantly lower mortality than non-treated birds. Additionally, gross lesion severity was reduced due to probiotic supplementation in all intestinal segments evaluated. These results suggest that <jats:italic>in ovo<\/jats:italic> supplementation of probiotics may improve early performance and provide protection against a mixed <jats:italic>Eimeria<\/jats:italic> infection.<\/jats:p>","DOI":"10.3920\/bm2016.0080","type":"journal-article","created":{"date-parts":[[2016,10,11]],"date-time":"2016-10-11T13:20:48Z","timestamp":1476192048000},"page":"699-706","source":"Crossref","is-referenced-by-count":44,"title":["Effects of in ovo supplementation of probiotics on performance and immunocompetence of broiler chicks to an Eimeria challenge"],"prefix":"10.1163","volume":"7","author":[{"given":"C.M.","family":"Pender","sequence":"first","affiliation":[{"name":"Avian Immunobiology Laboratory, Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA 24061, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Kim","sequence":"additional","affiliation":[{"name":"Avian Immunobiology Laboratory, Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA 24061, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.D.","family":"Potter","sequence":"additional","affiliation":[{"name":"Avian Immunobiology Laboratory, Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA 24061, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.M.","family":"Ritzi","sequence":"additional","affiliation":[{"name":"Avian Immunobiology Laboratory, Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA 24061, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Young","sequence":"additional","affiliation":[{"name":"Star Labs\/Forage Research, Inc., P.O. Box 77, Clarksdale, MO 64430, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.A.","family":"Dalloul","sequence":"additional","affiliation":[{"name":"Avian Immunobiology Laboratory, Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA 24061, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","reference":[{"key":"atypb1","first-page":"471","volume":"6","journal-title":"Global Veterinaria"},{"key":"atypb2","first-page":"27","volume":"1","journal-title":"International Journal of Applied Poultry Research"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.15.1.58-65.2002"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.3920\/BM2014.0062"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.3382\/ps.0711781"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1637\/7306-11150R"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1586\/14760584.5.1.143"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1093\/ps\/82.1.62"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1016\/j.cimid.2005.09.001"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1093\/ps\/76.1.179"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2672.1989.tb05105.x"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1093\/ps\/83.5.788"},{"key":"atypb13","first-page":"1079","volume":"25","journal-title":"Biotechnology in Animal Husbandry"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(70)90063-9"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.3923\/ijps.2004.361.364"},{"key":"atypb16","first-page":"296","volume":"43","journal-title":"Poultry Science"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1016\/j.cimid.2007.02.002"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1093\/ps\/86.1.63"},{"key":"atypb19","doi-asserted-by":"publisher","DOI":"10.1016\/j.cimid.2010.06.001"},{"key":"atypb20","doi-asserted-by":"publisher","DOI":"10.1093\/japr\/6.3.260"},{"key":"atypb21","doi-asserted-by":"publisher","DOI":"10.1093\/ps\/86.2.309"},{"key":"atypb22","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1590\/S1516-635X2012000200004","volume":"14","journal-title":"Revista Brasileira de Ci\u00eancia Av\u00edcola"},{"key":"atypb23","doi-asserted-by":"publisher","DOI":"10.1079\/AHR2005103"},{"key":"atypb24","first-page":"1308","volume":"6","journal-title":"Journal of Animal and Veterinary Advances"},{"key":"atypb25","doi-asserted-by":"publisher","DOI":"10.3382\/ps.2011-01342"},{"key":"atypb26","first-page":"340","volume":"45","journal-title":"Indian Journal of Poultry Science"},{"key":"atypb27","doi-asserted-by":"publisher","DOI":"10.3382\/ps.2011-01560"},{"key":"atypb28","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2011.05.021"},{"key":"atypb29","doi-asserted-by":"publisher","DOI":"10.1080\/03079450802356995"},{"key":"atypb30","doi-asserted-by":"publisher","DOI":"10.3382\/ps.2011-01360"},{"key":"atypb31","doi-asserted-by":"publisher","DOI":"10.3382\/ps.2008-00091"}],"container-title":["Beneficial Microbes"],"original-title":[],"link":[{"URL":"https:\/\/brill.com\/view\/journals\/bm\/7\/5\/article-p699_11.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/brill.com\/downloadpdf\/journals\/bm\/7\/5\/article-p699_11.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/brill.com\/downloadpdf\/journals\/bm\/7\/5\/article-p699_11.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T08:43:12Z","timestamp":1713343392000},"score":1,"resource":{"primary":{"URL":"https:\/\/brill.com\/view\/journals\/bm\/7\/5\/article-p699_11.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,30]]},"references-count":31,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.3920\/bm2016.0080","relation":{},"ISSN":["1876-2883","1876-2891"],"issn-type":[{"value":"1876-2883","type":"print"},{"value":"1876-2891","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,30]]}}}