{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T17:40:27Z","timestamp":1760204427994},"reference-count":31,"publisher":"SLACK, Inc.","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Gerontol Nurs"],"published-print":{"date-parts":[[2010,6]]},"abstract":"<jats:p>\n            Vitamin B\n            <jats:sub>12<\/jats:sub>\n            deficiency is a common but underrecognized problem in older adults. Historically, B\n            <jats:sub>12<\/jats:sub>\n            deficiency was diagnosed once a severe\n            <jats:italic>pernicious anemia<\/jats:italic>\n            developed. Scientific developments have led to a new understanding of a broader spectrum of B\n            <jats:sub>12<\/jats:sub>\n            deficiency and identification of a milder form of deficiency associated with food\/vitamin B\n            <jats:sub>12<\/jats:sub>\n            malabsorption. Using an individual example, this article describes the functional impact of vitamin B\n            <jats:sub>12<\/jats:sub>\n            deficiency and highlights modern approaches to diagnosis and treatment.\n          <\/jats:p>","DOI":"10.3928\/00989134-20100504-08","type":"journal-article","created":{"date-parts":[[2010,5,27]],"date-time":"2010-05-27T19:37:19Z","timestamp":1274989039000},"page":"16-21","source":"Crossref","is-referenced-by-count":2,"title":["Functional Implications of Vitamin B\n            <sub>12<\/sub>\n            Deficiency"],"prefix":"10.3928","volume":"36","author":[{"given":"Mary P.","family":"Cadogan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2008.26947A"},{"key":"e_1_3_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2005.02.026"},{"key":"e_1_3_1_4_1","first-page":"537","article-title":"B12 deficiency: A look beyond pernicious anemia","volume":"56","author":"Andr\u00e8s E.","year":"2007","unstructured":"Andr\u00e8s, E., Federici, L., Affenberger, S., Vidal-Alaball, J., Loukili, N.H., Zimmer, J.. 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British Journal of Haemotology, 111, 407\u2013415.","journal-title":"British Journal of Haemotology"},{"key":"e_1_3_1_10_1","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2006.080382"},{"key":"e_1_3_1_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcn138"},{"issue":"3","key":"e_1_3_1_12_1","first-page":"30","article-title":"Vitamin B12 deficiency. Recognizing subtle symptoms in older adults","volume":"58","author":"Dharmarajan T.S.","year":"2003","unstructured":"Dharmarajan, T.S., Adiga, G.U., & Norkus, E.P. (2003). Vitamin B12 deficiency. Recognizing subtle symptoms in older adults. Geriatrics, 58(3), 30\u201338.","journal-title":"Geriatrics"},{"key":"e_1_3_1_13_1","first-page":"385","article-title":"A case of progressive pernicious anemia (idiopathic of Addison)","volume":"5","author":"Gardner W.","year":"1877","unstructured":"Gardner, W., & Osler, W. (1877). A case of progressive pernicious anemia (idiopathic of Addison). 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Dietary reference intakes for thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin, and choline. Retrieved from the National Academies Press website: http:\/\/www.nap.edu\/catalog.php?record_id=6015"},{"key":"e_1_3_1_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.160.9.1349"},{"key":"e_1_3_1_19_1","first-page":"169","article-title":"Romberg's test","volume":"49","author":"Khasnis A.","year":"2003","unstructured":"Khasnis, A., & Gokula, R.M. (2003). Romberg's test. Journal of Postgraduate Medicine, 49, 169\u2013172.","journal-title":"Journal of Postgraduate Medicine"},{"key":"e_1_3_1_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02982659"},{"key":"e_1_3_1_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1926.02680070016005"},{"key":"e_1_3_1_22_1","unstructured":"National Institutes of Health Office of Dietary Supplements. (2009). Dietary supplement fact sheet: Vitamin B12 . 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