{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T04:22:55Z","timestamp":1683174175903},"reference-count":9,"publisher":"SLACK, Inc.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthopedics"],"published-print":{"date-parts":[[1981,1]]},"abstract":"<jats:p>ABSTRACT: The natural history of multiple epiphyseal dysplasia in a 74-member kindred was monitored for 17 years. Genetic transmission was clearly autosomal dominant, with variable expressivity. Onset of symptoms, joint involvement, and severity of deformity in 24 definitely affected individuals were somewhat variable, though short stature and hip involvement were characteristic. In several cases patients displayed the clinical and radiographic course of such diverse diseases as Blount's, Perthes, and osteochondritis dissecans, suggesting a common developmental etiology. Longitudinal study suggests that non-weightbearing in the prepubertal patient may limit evolving hip deformity. Experience with surgical interventions is discussed.<\/jats:p>","DOI":"10.3928\/0147-7447-19810101-06","type":"journal-article","created":{"date-parts":[[2021,4,22]],"date-time":"2021-04-22T19:25:27Z","timestamp":1619119527000},"page":"38-46","source":"Crossref","is-referenced-by-count":2,"title":["MULTIPLE EPIPHYSEAL DYSPLASIA: A LONGITUDINAL FAMILY STUDY"],"prefix":"10.3928","volume":"4","author":[{"given":"William L","family":"Lehman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas M","family":"Murray","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_1","doi-asserted-by":"crossref","unstructured":"1. Anderson CE Jackson TC Harper JA et al. Morquio's disease and dysplasia epiphysialis multiplex. J Bone joint Surg 1962; 44A:295-306.","DOI":"10.2106\/00004623-196244020-00006"},{"key":"e_1_3_1_3_1","doi-asserted-by":"crossref","unstructured":"2. Rubin P. Dynamic Classification of Bone Dysplasias. Chicago Year Book Medical Publishers 1964.","DOI":"10.1097\/00001888-196411000-00025"},{"key":"e_1_3_1_4_1","unstructured":"3. Silverman FN. Dysplasies epiphysaires: Entit\u00e9 proteiforme. Ann de Radiol 1961; 4:833-867."},{"key":"e_1_3_1_5_1","doi-asserted-by":"crossref","unstructured":"4. Diamond LS. A family study of spondyloepiphyseal dysplasia. J Bone loint Surg 1970; 52A:8: 1587- 1594.","DOI":"10.2106\/00004623-197052080-00006"},{"key":"e_1_3_1_6_1","doi-asserted-by":"crossref","unstructured":"5. Mena JR Pearson EO. Multiple epiphyseal dysplasia: A. family case report. JAMA 1976; 236:2629-2633.","DOI":"10.1001\/jama.236.23.2629"},{"key":"e_1_3_1_7_1","doi-asserted-by":"crossref","unstructured":"6. Murphy MC Shine IB Stevens DB. Multiple epiphyseal dysplasia: Report of a pedigree. J Bone Joint Surg 1973; 55A:4:814-820.","DOI":"10.2106\/00004623-197355040-00016"},{"key":"e_1_3_1_8_1","unstructured":"7. Rimoin DL. Pathogenetic mechanisms of limb malformation in the skeletal dysplasias: Birth defects: Original article series 1977; 13:339-3S3."},{"key":"e_1_3_1_9_1","doi-asserted-by":"crossref","unstructured":"8. Felman AH. Multiple epiphyseal dysplasia: Three cases with unusual vertebral abnormalities. Radiology 1969; 93:119-125.","DOI":"10.1148\/23.1.119"},{"key":"e_1_3_1_10_1","unstructured":"9. Fairbank T. An Atlas of General Affections of the Skeleton. Edinburgh ES Livingston Ltd 1951."}],"container-title":["Orthopedics"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T04:13:56Z","timestamp":1683087236000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/0147-7447-19810101-06"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,1]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1981,1]]}},"alternative-id":["10.3928\/0147-7447-19810101-06"],"URL":"https:\/\/doi.org\/10.3928\/0147-7447-19810101-06","relation":{},"ISSN":["0147-7447","1938-2367"],"issn-type":[{"value":"0147-7447","type":"print"},{"value":"1938-2367","type":"electronic"}],"subject":[],"published":{"date-parts":[[1981,1]]}}}