{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T20:36:08Z","timestamp":1793219768332,"version":"4.5.0"},"reference-count":29,"publisher":"SLACK, Inc.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthopedics"],"published-print":{"date-parts":[[2008,3]]},"abstract":"<jats:sec>\n            <jats:title>Educational Objectives<\/jats:title>\n            <jats:p>\n              <jats:bold>As a result of reading this article, physicians should be able to:<\/jats:bold>\n              <jats:list list-type=\"order\">\n                <jats:list-item>\n                  <jats:label>1.<\/jats:label>\n                  <jats:p>Describe the appropriate clinical workup for von Willebrand disease.<\/jats:p>\n                <\/jats:list-item>\n                <jats:list-item>\n                  <jats:label>2.<\/jats:label>\n                  <jats:p>Discuss the demographics of von Willebrand disease.<\/jats:p>\n                <\/jats:list-item>\n                <jats:list-item>\n                  <jats:label>3.<\/jats:label>\n                  <jats:p>Recognize the musculoskeletal manifestations of von Willebrand disease.<\/jats:p>\n                <\/jats:list-item>\n                <jats:list-item>\n                  <jats:label>4.<\/jats:label>\n                  <jats:p>Describe the most common treatments for the disease and its orthopedic sequelae.<\/jats:p>\n                <\/jats:list-item>\n              <\/jats:list>\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.3928\/01477447-20080301-22","type":"journal-article","created":{"date-parts":[[2009,3,12]],"date-time":"2009-03-12T16:31:25Z","timestamp":1236875485000},"page":"1-5","source":"Crossref","is-referenced-by-count":5,"title":["Orthopedic Manifestations and Management of Patients With von Willebrand Disease"],"prefix":"10.3928","volume":"31","author":[{"given":"LT Leo T.","family":"Kroonen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CPT Bruce L.","family":"Gillingham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LCDR Matthew T.","family":"Provencher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_2","volume-title":"Williams Hematology","author":"Gralnick HR","year":"1995","unstructured":"Gralnick HR, Ginsburg D. von Willebrand disease. In: Beutler A, Lichtman MA, Coller BS, Kipps TJ, eds. Williams Hematology. 5th ed. New York: McGraw-Hill; 1995.","edition":"5"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0266-4356(98)90178-4"},{"issue":"4","key":"e_1_3_1_4_2","first-page":"366","article-title":"Prevalence, pathophysiology, diagnosis and treatment of von Willebrand syndrome in orthopaedic trauma patients","volume":"28","author":"Kurth AA","year":"1999","unstructured":"Kurth AA, Ludwig G, Scharrer I. Prevalence, pathophysiology, diagnosis and treatment of von Willebrand syndrome in orthopaedic trauma patients. Orthopade. 1999; 28(4):366\u2013374.","journal-title":"Orthopade"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-199404000-00004"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2143(99)90100-2"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2516.1998.440665.x"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199801000-00006"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.65B4.6874715"},{"key":"e_1_3_1_10_2","first-page":"197","article-title":"Orthopedic problems in hemophilia","volume":"138","author":"Houghton GR","year":"1979","unstructured":"Houghton GR, Duthie RB. Orthopedic problems in hemophilia. Clin Orthop Relat Res. 1979; 138:197\u2013216.","journal-title":"Clin Orthop Relat Res"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200403000-00019"},{"issue":"4","key":"e_1_3_1_12_2","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1007\/PL00003618","article-title":"Joint preserving operations and endoprosthetic substitutions in hemophiliacs. Indications and long term results","volume":"28","author":"Hovy L","year":"1999","unstructured":"Hovy L. Joint preserving operations and endoprosthetic substitutions in hemophiliacs. Indications and long term results. Orthopade. 1999; 28(4):356\u2013365.","journal-title":"Orthopade"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-5898(20)30662-3"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.3928\/0147-7447-19970801-10"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1613540"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.1984.tb02568.x"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-197961010-00013"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.60B3.681415"},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.63B2.7217153"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.1984.tb02567.x"},{"key":"e_1_3_1_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.1984.tb02570.x"},{"key":"e_1_3_1_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.1984.tb02572.x"},{"key":"e_1_3_1_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.1984.tb02573.x"},{"key":"e_1_3_1_24_2","first-page":"192","article-title":"Total knee replacement in hemophilia","volume":"125","author":"Marmor L","year":"1977","unstructured":"Marmor L. Total knee replacement in hemophilia. Clin Orthop Relat Res. 1977; 125:192\u2013195.","journal-title":"Clin Orthop Relat Res"},{"key":"e_1_3_1_25_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-197759040-00003"},{"key":"e_1_3_1_26_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199173070-00008"},{"key":"e_1_3_1_27_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2516.2002.00637.x"},{"key":"e_1_3_1_28_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2516.9.s1.11.x"},{"key":"e_1_3_1_29_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2003-41346"},{"key":"e_1_3_1_30_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2516.2003.00702.x"}],"container-title":["Orthopedics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.healio.com\/doiresolver?doi=10.3928\/01477447-20080301-22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T18:24:14Z","timestamp":1752776654000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.healio.com\/doi\/10.3928\/01477447-20080301-22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3]]},"references-count":29,"aliases":["10.3928\/01477447-20080301-23"],"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,3]]}},"alternative-id":["10.3928\/01477447-20080301-22"],"URL":"https:\/\/doi.org\/10.3928\/01477447-20080301-22","relation":{},"ISSN":["0147-7447","1938-2367"],"issn-type":[{"value":"0147-7447","type":"print"},{"value":"1938-2367","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,3]]}}}