{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T09:55:52Z","timestamp":1780653352439,"version":"3.54.1"},"reference-count":30,"publisher":"SLACK, Inc.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthopedics"],"published-print":{"date-parts":[[2011,1,3]]},"abstract":"<jats:p>Deep vein thrombosis (DVT) is an important complication following total knee arthroplasty (TKA). However, the incidence of DVT is generally underestimated due to subclinical or minor symptoms and signs. In Western countries, prophylactic agents against DVT are administered routinely after TKA. However, in Asia, no regular prophylaxis is generally given to patients undergoing TKA.<\/jats:p>\n          <jats:p>\n            This article presents a prospective study evaluating the incidence of DVT in 724 consecutive Taiwanese patients who underwent TKA without prophylactic anticoagulation therapy. Of these, 328 patients (45.3%) showed positive Homan\u2019s sign with calf swelling &gt;3 cm. Ultrasonographic examination revealed the overall incidence of DVT to be 8.6% (62\/724). The incidence of DVT was significantly higher in women (\n            <jats:italic>P<\/jats:italic>\n            =.035), in patients who underwent bilateral TKA (\n            <jats:italic>P<\/jats:italic>\n            =.002), and in patients with a body mass index \u226530 kg\/m\n            <jats:sup>2<\/jats:sup>\n            (\n            <jats:italic>P<\/jats:italic>\n            =.026). The incidence of DVT appeared to be increased in patients with higher tourniquet time; however, the difference was not statistically significant. In all of the suspected cases of DVT, the symptoms subsided after the administration of enoxaparin with uneventful follow-up. No patient developed pulmonary embolism.\n          <\/jats:p>\n          <jats:p>Our results showed a relatively high incidence of DVT in an Asian population following TKA. We therefore consider that following TKA, prophylactic anticoagulation therapy should be administered to high-risk patients.<\/jats:p>","DOI":"10.3928\/01477447-20101123-05","type":"journal-article","created":{"date-parts":[[2011,1,6]],"date-time":"2011-01-06T14:17:01Z","timestamp":1294323421000},"source":"Crossref","is-referenced-by-count":26,"title":["Deep Vein Thrombosis After Total Knee Arthroplasty in Asian Patients Without Prophylactic Anticoagulation"],"prefix":"10.3928","volume":"34","author":[{"given":"Lien-Hsiang","family":"Chung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Ming","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng-Fong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tain-Hsiung","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chien-Lin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2308","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.D.03033"},{"issue":"273","key":"e_1_3_1_3_2","first-page":"119","article-title":"Factors leading to low incidence of deep vein thrombosis after cementless and cemented total knee arthroplasty","author":"Kim YH","year":"1991","unstructured":"Kim YH, Kim VE. Factors leading to low incidence of deep vein thrombosis after cementless and cemented total knee arthroplasty. Clin Orthop Relat Res. 1991; (273):119\u2013124.","journal-title":"Clin Orthop Relat Res"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.72B5.2211755"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0883-5403(97)90131-5"},{"issue":"4","key":"e_1_3_1_6_2","first-page":"439","article-title":"Use of low molecular weight heparin for prevention of deep vein thrombosis in total knee arthroplasty\u2014a study of its efficacy in an Asian population","volume":"29","author":"Fong YK","year":"2000","unstructured":"Fong YK, Ruban P, Yeo SJ, et al. Use of low molecular weight heparin for prevention of deep vein thrombosis in total knee arthroplasty\u2014a study of its efficacy in an Asian population. 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